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Showing 73–96 of 138 matching trials from the live ClinicalTrials.gov search.
Conditions
Acute Pain
Interventions
DFN-15 (Celecoxib Oral Solution) 62.5 mg, DFN-15 (Celecoxib Oral Solution) 125 mg, DFN-15 (Celecoxib Oral Solution) 250 mg, Placebo
Drug
Lead sponsor
Dr. Reddy's Laboratories Limited
Industry
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Dental Pain
Interventions
N1539, placebo, Motrin
Drug
Lead sponsor
Alkermes, Inc.
Industry
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Pain, Postoperative Pain, Pain, Acute
Interventions
MR-107A-01, Placebo
Drug
Lead sponsor
Mylan Inc.
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Dental Pain
Interventions
Oxycodone, Buprenorphine, Placebo Film, Placebo Capsule
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years to 45 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
3
States / cities
Austin, Texas • San Marcos, Texas • Salt Lake City, Utah
Conditions
Pain, Postoperative
Interventions
Naproxen Sodium (Aleve, BAY117031), Ibuprofen (Advil), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
16 Years to 40 Years
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Withdrawn Not applicable Interventional Accepts healthy volunteers

Local Anesthesia and Analgesics in Endodontic Pain

NCT01982799
Conditions
Odontalgia
Interventions
Oral placebo, Oral ibuprofen, oral naproxen, oral acetaminophen/hydrocodone + ibuprofen
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed No phase listed Observational Accepts healthy volunteers

DPBRN Persistent Pain and Root Canal Therapy

NCT01201668
Conditions
Root Canal Therapy, Persistent Tooth Pain
Interventions
Not listed
Lead sponsor
Dental Practice-Based Research Network
Network
Eligibility
19 Years to 70 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
7
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more
Conditions
Dental Fear, Anesthesia, Local, Pediatric Dentistry
Interventions
Synapse TENS device, Topical anesthetic gel
Device · Drug
Lead sponsor
Boston University
Other
Eligibility
6 Years to 14 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Utility of Pharmacogenomic Testing and Postoperative Dental Pain Outcomes

NCT02932579
Conditions
Pain
Interventions
Pharmacogenomic Testing, Ibuprofen, hydroxycontin/acetominophen, acetominophen, Oxycontin/acetominophen
Other · Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 35 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Rochester, New York
Terminated Phase 2 Interventional Results available

Neurotropin to Treat Chronic Neuropathic Pain

NCT00006289
Conditions
Complex Regional Pain Syndrome Type I, Complex Regional Pain Syndrome Type II
Interventions
Placebo, Neurotropin
Drug
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Emergency Department Visit, Odontalgia
Interventions
Clinical decision support tool
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Study Comparing the Efficacy of Two Ibuprofen Formulations

NCT00740857
Conditions
Pain
Interventions
placebo, ibuprofen Formulation 1, ibuprofen Formulation 2
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
16 Years to 40 Years
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Not listed Not applicable Interventional Accepts healthy volunteers

Effectiveness of GentleWave System in Endodontic Treatment

NCT06518304
Conditions
Pain, Postoperative, Root Canal Infection, Endodontically Treated Teeth
Interventions
GentleWave, Conventional Protocol
Other
Lead sponsor
University of Salamanca
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Manhattan, New York
Conditions
Pain, Dental Impaction
Interventions
Ketorolac tromethamine, Placebo
Drug
Lead sponsor
Egalet Ltd
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Austin, Texas
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis

NCT01951820
Conditions
Anesthesia of Mucous Membrane
Interventions
Pliaglis, Benzocaine, Articaine
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Osseointegrated Dental Implantation, Pain, Acute
Interventions
Naproxen, Acetaminophen, Tramadol
Drug
Lead sponsor
Hersh, Elliot V., DMD, MS, PhD
Individual
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Tool Design on Hand Pain in Dental Practitioners

NCT01332760
Conditions
Shoulder Pain
Interventions
narrow diameter heavy dental tool, large diameter light weight tool
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Richmond, California
Conditions
Pain
Interventions
Novel Ibuprofen, Acetaminophen, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
16 Years to 40 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Pain, Procedural
Interventions
Lidocaine
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
Up to 6 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Dental Anxiety, Pain
Interventions
Nitrous Oxide, Midazolam
Drug
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
3 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Pain
Interventions
Naproxen Sodium (Aleve, BAY117031), Hydrocodone/Acetaminophen, Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 40 Years
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Postoperative Pain
Interventions
EXPAREL and Local Anesthetics, Oral Opioid and Local Anesthetics
Procedure
Lead sponsor
Bellaire Facial Surgery Center
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
3
States / cities
Atlanta, Georgia • Houston, Texas • The Woodlands, Texas
Conditions
Post-op Pain
Interventions
Neupro® transdermal patch/placebo
Drug
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Greenville, North Carolina
Conditions
Orthodontic Appliance, Pain, Transcutaneous Electric Nerve Stimulation, Orthodontic Appliance Complication
Interventions
Active TENS Device, Intervention 2: Placebo/Sham Device
Device
Lead sponsor
University of the Pacific
Other
Eligibility
12 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Francisco, California