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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dental Phobia Clear all
Completed Not applicable Interventional Results available

Comparing Brief Relaxation Period to Virtual Reality Period in Reducing Dental Anxiety Prior to Root Canal Treatment

NCT05720897
View directory record Official record
Conditions
Dental Anxiety
Interventions
Auditory Alone, Relaxation Virtual Reality
Other · Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Triazolam and Midazolam for Anxiolysis During Dental Treatment in the Pediatric Patient

NCT03360123
View directory record Official record
Conditions
Dental Anxiety
Interventions
Midazolam Hydrochloride 2Mg/mL Syrup, Triazolam 0.125 MG
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
7 Years to 17 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Jun 10, 2026, 10:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sensory Adapted Dental Environments to Enhance Oral Care for Children With and Without Dental Fear and Anxiety

NCT06912854
View directory record Official record
Conditions
Dental Fear and Anxiety
Interventions
Sensory Adapted Dental Environment, Video-based Modeling
Other
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 12 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality in Pediatric Dentistry

NCT05585905
View directory record Official record
Conditions
Behavior, Child, Anxiety, Dental
Interventions
Virtual Reality, Basic Behavior Guidance Techniques
Device · Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Long Beach, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Results available

Efficacy of an Internet-based Intervention for Dental Anxiety

NCT03680755
View directory record Official record
Conditions
Dental Anxiety
Interventions
Internet-based intervention for dental anxiety
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 75 Years
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Jun 10, 2026, 10:06 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Impact of Medical Play in the Dental Clinic Setting on the Cooperation of Neurotypical Patients

NCT05571423
View directory record Official record
Conditions
Dental Phobia, Dental Anxiety, Oral Aversion
Interventions
Medical Play, Routine Play
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 10 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Results available

Nonpharmacologic Reduction of Periprocedural Distress and Drug Use

NCT03328208
View directory record Official record
Conditions
Dental Anxiety, Dental Pain, Drug Use, Opioid Use
Interventions
Comfort Talk® app, White Noise app
Other
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pre-Visit Positive Imagery in Reducing Dental Anxiety

NCT06058533
View directory record Official record
Conditions
Dental Anxiety
Interventions
Previsit Imagery Picturebook
Other
Lead sponsor
University of Southern California
Other
Eligibility
4 Years to 10 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Jun 10, 2026, 10:06 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children

NCT03779659
View directory record Official record
Conditions
Dental Fear, Anesthesia, Local, Pediatric Dentistry
Interventions
Synapse TENS device, Topical anesthetic gel
Device · Drug
Lead sponsor
Boston University
Other
Eligibility
6 Years to 14 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 7, 2021 · Synced Jun 10, 2026, 10:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Stepped Care Approach to Treating Dental Fear

NCT06024395
View directory record Official record
Conditions
Dental Fear
Interventions
A stepped-care approach to the treatment of dental fear; Dental Fearless
Behavioral
Lead sponsor
New York University
Other
Eligibility
13 Years to 99 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Flumazenil Reversal of Oral Triazolam

NCT00695630
View directory record Official record
Conditions
Dental Anxiety
Interventions
Flumazenil, Placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 11, 2008 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional

Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities

NCT03218462
View directory record Official record
Conditions
Developmental Disability, Intellectual Disability, Dental Anxiety
Interventions
Sensory Adapted Dental Environment (SADE)
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
6 Years to 21 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer Assisted Relaxation Learning for Dental Offices

NCT00609648
View directory record Official record
Conditions
Dental Anxiety
Interventions
Computer Assisted Relaxation Learning, Pamphlet
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
5
States / cities
Corvallis, Oregon • West Linn, Oregon • Bremerton, Washington + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2013 · Synced Jun 10, 2026, 10:06 AM EDT
Not listed Phase 4 Interventional

Nitrous Oxide Prior to Intranasal Midazolam for Moderate Dental Sedation in Pediatric Patients

NCT04083105
View directory record Official record
Conditions
Dental Anxiety, Pain
Interventions
Nitrous Oxide, Midazolam
Drug
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
3 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Virtual Reality Relaxation on the Anxiety Levels

NCT06804967
View directory record Official record
Conditions
Anxiety
Interventions
virtual reality relaxation headset
Device
Lead sponsor
Indiana University
Other
Eligibility
13 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jun 10, 2026, 10:06 AM EDT
Terminated Not applicable Interventional

Reducing Anxiety in Pediatric Dental Patients Through Passive Music Therapy

NCT03943836
View directory record Official record
Conditions
Anxiety, Dental
Interventions
Music
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
9 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2022 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Phase 3 Interventional Results available

A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients

NCT05126459
View directory record Official record
Conditions
Anxiety, Dental, Dental Decay
Interventions
Regimen 1, Regimen #2, Regimen #3
Combination Product
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 7 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Handheld Mirror to Improve Child's Behavior During Dental Treatment

NCT02366520
View directory record Official record
Conditions
Behavior
Interventions
handheld mirror
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
3 Years to 17 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Jun 10, 2026, 10:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining Stress Salivary Biomarkers in Pediatric Patients Undergoing Dental Procedures

NCT06730425
View directory record Official record
Conditions
Dental Anxiety, Dental Fear, Stress, Pediatric Population
Interventions
Not listed
Lead sponsor
Midwestern University
Other
Eligibility
7 Years to 17 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dissemination of a Brief Dental Fear Intervention

NCT05082298
View directory record Official record
Conditions
Dental Fear
Interventions
Dental FearLess app, In-Chair Treatment Protocol
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years to 100 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Jun 10, 2026, 10:06 AM EDT
Enrolling by invitation No phase listed Observational

Impact of Dental Desensitization Facilitated by a Child Life Specialist Distress and Cooperation

NCT06620289
View directory record Official record
Conditions
Desensitization, Dental Anxiety, Dental Care, Distress, Emotional, Cooperation, Patient
Interventions
Dental Desensitization Clinic
Behavioral
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
2 Years to 25 Years
Enrollment
59 participants
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Results available

Clinical Management of Anxiety and Access to Health Care

NCT02081365
View directory record Official record
Conditions
Dental Anxiety
Interventions
Computerized Dental Anxiety Treatment
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 70 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Jun 10, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dental Fear Among Children With Autism Spectrum Disorders

NCT01784276
View directory record Official record
Conditions
Dental Fear
Interventions
Video
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2013 · Synced Jun 10, 2026, 10:06 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?

NCT06057090
View directory record Official record
Conditions
Therapy Animals, Dental Anxiety, Child Behavior, Anesthesia, Local
Interventions
Therapy Dog
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
3 Years to 7 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jun 10, 2026, 10:06 AM EDT