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Showing 25–34 of 10 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dentinal Hypersensitivity Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity

NCT01592851
View directory record Official record
Conditions
Dentine Hypersensitivity
Interventions
Stannous Fluoride, Sodium Monofluorophosphate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Dentinal Hypersensitivity Reduction

NCT06244290
View directory record Official record
Conditions
Dentinal Hypersensitivity
Interventions
Colgate SNF, Sensodyne Extra Whitening, Colgate Fluoride (CDC)
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Costa Mesa, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study to Investigate the Efficacy of a Toothpaste in Providing Relief From Dentinal Hypersensitivity

NCT01494649
View directory record Official record
Conditions
Dentinal Sensitivity, Hypersensitivity
Interventions
Test Toothpaste, Negative Control Toothpaste
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 7, 2013 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

NCT02542943
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Experimental Oral Rinse 1, Experimental Oral Rinse 2, Placebo Oral Rinse, Standard fluoride toothpaste
Device · Other · Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Two Water-Based Potassium Oxalate Desensitizers on Dental Hypersensitivity

NCT02152826
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Potassium oxalate
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity

NCT02293044
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Crest® Sensi-Stop™ Strips
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hypersensitivity

NCT07257042
View directory record Official record
Conditions
Hypersensitivity
Interventions
Toothpaste containing 8% Arginine, Colgate Cavity Protection Toothpaste
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity

NCT02832375
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
stannous fluoride, sodium monofluorophosphate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 24, 2017 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Caries Prevention Products & Dentinal Hypersensitivity

NCT02136576
View directory record Official record
Conditions
Hypersensitivity
Interventions
Sensodyne, Crest Cavity Protection & MI Paste Plus, Clinpro 5000
Device
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Jul 22, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Safety and Efficacy of an Oxalate Gel or Negative Control on Dentinal Hypersensitivity

NCT02189382
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Potassium Oxalate, Water
Device · Other
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 19, 2018 · Synced Jul 22, 2026, 9:43 PM EDT