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ClinicalTrials.gov public records Last synced Nov 2, 2026, 2:59 PM EST

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Showing 481–504 of 4,840 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depressed Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Remote Home Support Coaches (SOCIAL Study)

NCT04772820
View directory record Official record
Conditions
Malnutrition, Isolation, Depression, Anxiety, Sedentary Behavior, Loneliness
Interventions
Telephone-based coaching
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
75 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Baltimore, Maryland • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional

Developing Mental Health Supports for Autistic Students

NCT04926090
View directory record Official record
Conditions
Autism Spectrum Disorder, Depression, Anxiety
Interventions
Emotional Support Plan - Clinician Guided (ESP-C), Emotional Support Plan - Self Guided (ESP-S)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
17 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Nov 2, 2026, 2:59 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Concurrent TMS-fMRI

NCT06633913
View directory record Official record
Conditions
Healthy Control, Depression
Interventions
spTMS-TBS-spTMS
Device
Lead sponsor
Jing Jiang
Other
Eligibility
18 Years to 65 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Nov 2, 2026, 2:59 PM EST
Recruiting Not applicable Interventional

Parents and Babies Pilot

NCT07607613
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression (PPD)
Interventions
Parents and Babies Virtual Group Intervention, Parents and Babies Hybrid Group Intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Nov 2, 2026, 2:59 PM EST
Not listed Phase 3 Interventional Accepts healthy volunteers

Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers

NCT01892813
View directory record Official record
Conditions
Nicotine Dependence, Tobacco Use
Interventions
Nicotine replacement therapy - Transdermal nicotine patch, Nicotine replacement therapy - Nicotine gum, Nicotine replacement therapy - Nicotine lozenge, Bupropion, Varenicline, Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum, Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge, Combination pharmacotherapy - Transdermal nicotine patch + bupropion, Tobacco quitline referral, Tailored behavioral intervention, Alcohol use risk reduction, Behavioral activation for depressive symptoms, Behavioral management of postcessation weight gain
Drug · Behavioral
Lead sponsor
Mark Vander Weg
Other
Eligibility
18 Years to 99 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional Results available

Research Aimed at Improving Both Mood and Weight

NCT02246413
View directory record Official record
Conditions
Depression, Obesity
Interventions
RAINBOW Intervention Program
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
409 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Nov 2, 2026, 2:59 PM EST
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE

NCT05601206
View directory record Official record
Conditions
Cancer, Depression, Fatigue, Pain, Sleep
Interventions
Stepped collaborative care intervention, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2032
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Child STEPS for Youth Mental Health in Maine Sustainability

NCT03112304
View directory record Official record
Conditions
Anxiety, Depression, Trauma, Behavior Problems
Interventions
MATCH-ADTC, TRAC
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
6 Years to 15 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Nov 2, 2026, 2:59 PM EST
Suspended Not applicable Interventional Accepts healthy volunteers

Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression

NCT05933148
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Siemens 7T MRI, Sham Neurofeedback
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional

Postpartum Visit Timing and the Effect on Visit Attendance

NCT05399784
View directory record Official record
Conditions
Postpartum Disorder, Postpartum Depression, Postpartum Weight Retention, Breastfeeding, Satisfaction, Patient, Trust
Interventions
Early postpartum visit, Standard postpartum visit
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
13 Years to 50 Years · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Nov 2, 2026, 2:59 PM EST
Withdrawn Not applicable Interventional

Determinants in Antidepressant Outcomes

NCT00108316
View directory record Official record
Conditions
Depression
Interventions
Fluoxetine (Liquid Prozac)
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 27, 2013 · Synced Nov 2, 2026, 2:59 PM EST
Withdrawn Not applicable Interventional

Pacifiers and Breastfeeding Among Mothers at Risk for Postpartum Depression

NCT03709004
View directory record Official record
Conditions
Breastfeeding, Postpartum Depression
Interventions
Pacifier
Other
Lead sponsor
University of California, Davis
Other
Eligibility
12 Hours to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Nov 2, 2026, 2:59 PM EST
Recruiting Not applicable Interventional

SAINT in Postpartum Depression (PPD)

NCT07210255
View directory record Official record
Conditions
Postpartum Depression (PPD)
Interventions
SAINT Neuromodulation System, Sham SAINT Stimulation
Device
Lead sponsor
Magnus Medical
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
4
States / cities
Worcester, Massachusetts • New York, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Nov 2, 2026, 2:59 PM EST
Completed Phase 2 Interventional Results available

Optimizing the Effectiveness of Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment-Resistant Depression

NCT00093847
View directory record Official record
Conditions
Depression
Interventions
S-adenosyl methione (SAMe), Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2014 · Synced Nov 2, 2026, 2:59 PM EST
Completed Phase 2 Interventional

Treatment of Depression With Massage in HIV

NCT00033852
View directory record Official record
Conditions
Acquired Immunodeficiency Syndrome, HIV Infections, Depression
Interventions
Massage Therapy
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
16 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2008 · Synced Nov 2, 2026, 2:59 PM EST
Completed No phase listed Observational

Improving Adolescent Health Outcomes Through Preventive Care Transformation

NCT02244138
View directory record Official record
Conditions
Sexually Transmitted Diseases, Depression Diagnosis, Substance Use Disorders
Interventions
Adolescent CDSS
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 21 Years
Enrollment
2,831 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Integrating Text Messages Into the Mothers and Babies Course

NCT03420755
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression
Interventions
Mothers and Babies 1-on-1, Mothers and Babies Plus Text
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
16 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional Results available

Examining Changes in Microbiota Over the Course of PTSD Treatment

NCT04109196
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional Results available

Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults

NCT04258579
View directory record Official record
Conditions
Depression, Depression in Old Age, Elder Abuse, Anxiety
Interventions
PROTECT with Technology Augmentation
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
55 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Nov 2, 2026, 2:59 PM EST
Completed No phase listed Observational Accepts healthy volunteers Results available

Dynamic Neural Mechanisms of Brexanolone-induced Antidepressant Effects in Postpartum Depression

NCT05543746
View directory record Official record
Conditions
Postpartum Depression
Interventions
Brexanolone
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional

Virtual Behavioral Health Integration

NCT04106388
View directory record Official record
Conditions
Depression, Substance Use Disorder, Anxiety
Interventions
Virtual Behavioral Health Integration
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
5,777 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
20
States / cities
Albemarle, North Carolina • Charlotte, North Carolina • Concord, North Carolina + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Nov 2, 2026, 2:59 PM EST
Completed Not applicable Interventional Results available

College Student Stress: Transitions Over Time

NCT06583096
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Surveys, Supportive Text messages, Personalized Feedback (PF) Report
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
17 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Nov 2, 2026, 2:59 PM EST
Completed Phase 4 Interventional Results available

A Study of Infliximab for Treatment Resistant Major Depression

NCT00463580
View directory record Official record
Conditions
Depression
Interventions
Infliximab, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
25 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Nov 2, 2026, 2:59 PM EST
Completed Phase 2Phase 3 Interventional Results available

Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy

NCT02452060
View directory record Official record
Conditions
Pain, Postoperative Depression
Interventions
Ketamine, Placebo Comparator
Drug · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2020 · Synced Nov 2, 2026, 2:59 PM EST