Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Nov 3, 2026, 12:28 AM EST

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Showing 553–576 of 4,840 matching trials from the live ClinicalTrials.gov search.
Conditions
Depression, Heart Failure
Interventions
Behavioral Activation Therapy, Medication Management
Behavioral · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Resilience in Adolescent Development

NCT03458936
Conditions
Risk Assessment, Resilience, Psychological, Depression, Mood Disorders, Anxiety Disorders, Mental Health
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years to 24 Years
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2032
U.S. locations
1
States / cities
Dallas, Texas
Terminated Not applicable Interventional Accepts healthy volunteers

A Neuroimaging Study of Open-label Placebo in Depressed Adolescents

NCT04201106
Conditions
Depression
Interventions
Open Label Placebo with Rationale, Open Label Placebo without Rationale
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 18 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Observational Accepts healthy volunteers

Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents

NCT04783506
Conditions
Suicide and Depression
Interventions
Observational Study
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Generalized Anxiety Disorder
Interventions
CYB004, Psychotherapy
Drug · Behavioral
Lead sponsor
Cybin IRL Limited
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
6
States / cities
Hollywood, Florida • Miami Lakes, Florida • Atlanta, Georgia + 3 more
Conditions
COPD, Depression, Anxiety
Interventions
Step-CBT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Depression
Interventions
PRogram In Support of Moms (PRISM), MCPAP for Moms
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Worcester, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Recruiting Not applicable Interventional

Treatment of Depression Post-SCI

NCT04263285
Conditions
Depression, Spinal Cord Injuries
Interventions
rTMS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Major Depressive Disorder
Interventions
Brainsway Deep TMS System
Device
Lead sponsor
Brainsway
Industry
Eligibility
22 Years to 68 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
7
States / cities
Tuscaloosa, Alabama • Redlands, California • Palm Beach, Florida + 4 more
Conditions
Anhedonia, Depression
Interventions
High Reward - High Variance, High Reward - Low Variance
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
La Jolla, California
Conditions
Suicide, Bereavement
Interventions
WELL Behavioral Probe
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Smoking, Anxiety Disorders, Depression Disorders
Interventions
Nicotine Patch, Depression and Anxiety Smoking Cessation Treatment, Educational-Support Psychotherapy
Drug · Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Results available

High Pain Intervention in Cesarean Sections

NCT01298778
Conditions
Other Chronic Postoperative Pain
Interventions
Duramorph 150, Acetaminophen, Duramorph 300
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Depression, Suicidal Ideation
Interventions
Text2Connect
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 26 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
McMurray, Pennsylvania • Natrona Heights, Pennsylvania • Pittsburgh, Pennsylvania
Conditions
Diabetes, Depression, Insomnia, Hypertension
Interventions
Intervention arm - automated call and phone-based pharmacist counseling
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
38,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Depression, Depression, Postpartum
Interventions
Elemental calcium (as carbonate)
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Multiple Sclerosis, Depression
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Acute Pain, Burns, Adverse Drug Event, Respiratory Depression, Nausea and Vomiting, Postoperative
Interventions
Oliceridine, Historical opioid use
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Memphis, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers

BasketballRx: Game Changing Health

NCT07778433
Conditions
Pediatric Obesity, Pediatric Overweight, Anxiety, Depression Disorders, Childhood Obesity, Childhood Overweight, Mental Health, Adolescent Obesity
Interventions
BasketballRx
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
10 Years to 15 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Harrisburg, Pennsylvania
Completed Not applicable Interventional Results available

Feasibility of Depression Care Management by E-mail

NCT00755235
Conditions
Depression
Interventions
Depression care management by secure messaging
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Results available

Equity Using Interventions for Pain and Depression - Pilot Study

NCT05695209
Conditions
Chronic Pain, Depression, Health Equity
Interventions
Coaching and Decision Aid
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Developing an Integrated Model for Home Visitation

NCT02410109
Conditions
Depressive Symptoms
Interventions
SCRIPT integrated model
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of SKY Breath Meditation on Health and Well-being

NCT05523414
Conditions
Stress, Stress, Psychological, Stress, Physiological, Anxiety, Mental Well Being, Happiness, Resilience
Interventions
SKY
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 99 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Diego, California