Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 5:33 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 769–792 of 4,841 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Acute Coronary Syndrome, Heart Failure, Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions: Collaborative Care; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 3
States / cities: Boston, Massachusetts • Salem, Massachusetts

Conditions: Depression
Interventions: Deprexis, Active low-level light therapy, Sham low-level light therapy; Other · Device
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Depression
Interventions: brexanolone, placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lateral Gluteal Depression
Interventions: Biopsies; Diagnostic Test
Lead sponsor: Goldman, Butterwick, Fitzpatrick and Groff; Other
Eligibility: Female only
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Impulsive Behavior, Substance Abuse, HIV Risk Behavior, Anxiety, Depression, Criminogenic Thinking
Interventions: REVAMP, TAU; Behavioral
Lead sponsor: George Mason University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: Depression Anxiety Disorder
Interventions: Anxiety/Depression Program, Waitlist; Behavioral · Other
Lead sponsor: University of Southern Denmark; Other
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Major Depressive Disorder, Mood Disorders
Interventions: Computerized self-help program for depression; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 55 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Treatment Resistant Depression, Depressive Disorder, Treatment-Resistant, Depression, Bipolar
Interventions: SCC DBS; Device
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Hypertension, Diabetes, Postpartum, Pregnancy, Anxiety, Depression, Obesity
Interventions: Facilitated Transition to Primary Care; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms, Behavioral Problems, Child Overall Daily Functioning, Child and Guardian Relationship
Interventions: Trauma-focused Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 7 Years to 13 Years
Enrollment: 1,280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression, Bipolar Disorders, Mood Disorders
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 371 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 2
States / cities: Belmont, Massachusetts • Boston, Massachusetts

Conditions: MDD, Depression
Interventions: Transcranial Magnetic Stimulation; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 75 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depressive Disorder, Depression
Interventions: Sertraline; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 60 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 2
States / cities: St Louis, Missouri • Durham, North Carolina

Conditions: Pain, Chronic, Pain, Musculoskeletal, Anxiety
Interventions: dCBT; Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years and older
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Primary Health Care
Interventions: Integrated team care; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2001
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression, Major Depressive Disorder, Postpartum Depression
Interventions: Triple Chronotherapy, Usual Care; Behavioral · Other
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression, Stage I Breast Cancer, Stage IIIA Breast Cancer, Nutrition, Stage II Breast Cancer, Psychosocial Effects/Treatment, Quality of Life
Interventions: Not listed
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 26 participants
Timeline: 1999 – 2007
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Depression
Interventions: Positive Thoughts and Actions Program, Individual Support Program; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Major Depressive Disorder
Interventions: Levomilnacipran ER, Placebo; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 362 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2009
U.S. locations: 25
States / cities: Scottsdale, Arizona • Encino, California • Los Alamitos, California + 21 more

Conditions: Older Adults, Anxiety, Depression, Cardiac Surgery, Orthopedic Surgery, Major Surgical Resection of a Thoracic Malignancy, Major Surgical Resection of an Abdominal Malignancy
Interventions: Behavioral Activation, Medication Optimization; Behavioral · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 60 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Depression, Anxiety
Interventions: Collaborative Care; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Diabetes Mellitus, Type 2, Depression, Anxiety, Diet Habit
Interventions: Not listed
Lead sponsor: Sansum Diabetes Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Depression, ECT, Cognitive Change
Interventions: Soterix Medical Incorporated 4x1 adapter, Traditional ECT device; Device
Lead sponsor: University of New Mexico; Other
Eligibility: 50 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Depression, Major Depressive Episode, Bipolar Disorder
Interventions: MagVenture MagPro MST, RUL ECT; Device · Biological
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 55 Years to 90 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: New York, New York

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Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety

Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy

Study on Allopregnanolone and Depression in Perimenopausal Women

Analyze Previously Collected Biopsy Samples From Participants Who Completed the "SPLASH: Split-Body Randomized Clinical Trial of Poly-L-Lactic Acid for Adipogenesis and Volumization of the Hip Dell" Study

Evaluation of Re-Entry Values and Mindfulness Program (REVAMP) With Jail Inmates

Assessment of an App-based Anxiety/Depression Program in a Population With Elevated Anxiety/Depression

Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression?

Long Term Follow-up of Deep Brain Stimulation for Treatment-Resistant Depression

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya

Enhancing Outcomes, Reducing Costs: Evaluating Peer Support for Mood Disorders

Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder

Treatment Outcome of Vascular Depression

Assessment of the Efficacy of Digital CBT for Anxiety in Adults With Chronic Musculoskeletal Pain

Effectiveness of Team Treatment of Depression in Primary Care

Integrated Chronotherapy for Perinatal Depression

Factors Affecting Weight Gain in Women Receiving Adjuvant Chemotherapy for Breast Cancer

Middle School Matters Study

Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder

Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study

Collaborative Care for Treatment of Depression and Anxiety

Assessing Adherence to Digital Health Technologies Among Hispanic/Latino Adults With or At Risk of Type 2 Diabetes:

Amplitude Titration to Improve ECT Clinical Outcomes

Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults