Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 6, 2026, 10:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1105–1128 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Migraine, Headache, Depression
Interventions: Not listed
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Great Neck, New York

Conditions: Major Depressive Disorder
Interventions: venlafaxine (Effexor), placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Suicidal Ideation, Suicidal and Self-injurious Behavior, Depression
Interventions: iCHART/cASAP, Treatment as usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 17 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Itasca, Illinois

Conditions: Major Depressive Disorder
Interventions: Engage Therapy, Supportive Therapy; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 60 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Depression
Interventions: Interpersonal Psychotherapy for Adolescents, Enhanced Care; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 13 Years to 15 Years · Female only
Enrollment: 328 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2018
U.S. locations: 1
States / cities: Rochester, New York

Conditions: HIV Infections, Unstable Housing
Interventions: Not listed
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Chronic Pain, Depression
Interventions: Quiet Focus, Health Enhancement Program; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 50 Years to 120 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bipolar Disorder, Anxiety, Anxiety Disorders, Substance Use Disorders
Interventions: Quetiapine XR, Placebo for quetiapine XR; Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Bipolar Disorder
Interventions: L-Thyroxine, Placebo; Drug
Lead sponsor: Charite University, Berlin, Germany; Other
Eligibility: 18 Years to 65 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depression, Elderly
Interventions: Telepsychology, Face-to-face therapy; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 60 Years and older
Enrollment: 241 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Depressive Disorder, Major, Suicidal
Interventions: SLS-002, Placebo, Standard of care, Intranasal device; Drug · Other · Device
Lead sponsor: Seelos Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 21
States / cities: Orange, California • Panorama City, California • San Diego, California + 18 more

Conditions: Substance Use, Conduct Disorder, Depression, Anxiety
Interventions: Family Check-Up; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: Not listed
Enrollment: 593 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Major Depressive Disorder
Interventions: Duloxetine; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 45 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Major Depressive Disorder
Interventions: Not listed
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 25 Years
Enrollment: 251 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Depression, Anxiety, Palliative Care, Caregivers, Cancer
Interventions: Problem-Solving Therapy, Attention-matched Control, In-depth interviews; Behavioral · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 532 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: Columbia, Missouri • St Louis, Missouri • Philadelphia, Pennsylvania

Conditions: Refractory Depression, Treatment Resistant Depression
Interventions: psilocybin; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Depression, Obsessive-Compulsive Disorder, Anxiety Depression
Interventions: NeuroStar Advanced TMS Therapy System; Device
Lead sponsor: Neuronetics; Other
Eligibility: 5 Years to 120 Years
Enrollment: 156,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2035
U.S. locations: 1
States / cities: Malvern, Pennsylvania

Conditions: Depression, Anxiety, Stress
Interventions: Whole Liquid Egg, Plant-based Egg Substitute; Other
Lead sponsor: University of Idaho; Other
Eligibility: 19 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Moscow, Idaho

Conditions: Anhedonia, Depression and Suicide Ideation
Interventions: GET ActivE, Treatment As Usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 18 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania

Conditions: Depression, Anxiety Disorders, Stress Related Disorder
Interventions: Not listed
Lead sponsor: Singula Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2032
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression, Pregnancy
Interventions: Intervention, Control; Other
Lead sponsor: Lancaster General Hospital; Other
Eligibility: 13 Years and older · Female only
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: Lancaster, Pennsylvania • Philadelphia, Pennsylvania

Conditions: Bipolar Disorder, Depressive Episode
Interventions: Bezafibrate; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Suicidality, Sleep
Interventions: Treatment As Usual, Active Condition, Active Comparator; Other · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 55 Years and older
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 3
States / cities: Los Angeles, California • Augusta, Georgia • Pittsburgh, Pennsylvania

Conditions: Multiple Sclerosis, Major Depressive Disorder
Interventions: POWER-MS, FLEX-MS; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 64 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

A Quality of Life Study in Patients With Migraines

Electroencephalography (EEG) Biomarkers of Response in Depression

Optimizing Suicide Prevention Strategies for Pediatric Primary Care

Reward Function and Therapy for Late-Life Depression

Interpersonal Psychotherapy for Adolescent Girls

Engagement in HIV Primary Care Services

Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study

Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)

Supraphysiological Doses of Levothyroxine as Adjunctive Therapy in Bipolar Depression

Telepsychology-Service Delivery for Depressed Elderly Veterans

A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide

A Family Intervention for Adolescent Problem Behavior (AKA Project Alliance 2)

Assessment of Cognitive Functioning Before and After Treatment With Duloxetine

Sex, Hormones and Gamma-Aminobutyric Acid (GABA) in Stress Induced Anhedonia in Depression

Problem-Solving Therapy for Cancer Caregivers in Outpatient Palliative Care

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

Retrospective Analyses of TrakStar Database

Feasibility of Egg-Based Diet Interventions and Assessing Perinatal Mental Health

Get ActivE Study for At-risk Youth

An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression

Care Managers for Perinatal Depression (CMPD)

BezafibrateTreatment for Bipolar Depression: A Proof of Concept Study

Assessing Improvements in Mood and Sleep Trial

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis