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ClinicalTrials.gov public records Last synced Nov 7, 2026, 6:03 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1249–1272 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Major Depressive Disorder
Interventions: Mobile-device, plasticity-based adaptive cognitive treatment; Other
Lead sponsor: Posit Science Corporation; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Parenting, Parent-Child Relations, Self-regulation, Problem Behavior in School, School Adjustment, Depression
Interventions: Family Check-Up; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: Not listed
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Major Depressive Disorder
Interventions: Interpersonal psychotherapy for major depression following perinatal loss, Coping with Depression; Behavioral
Lead sponsor: Michigan State University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 199 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Depressive Symptoms, Anxiety, Parental Stress
Interventions: Family-based attachment-focused intervention, Psychoeducation; Behavioral
Lead sponsor: University of Delaware; Other
Eligibility: 11 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: Newark, Delaware • Philadelphia, Pennsylvania

Conditions: Depressive Disorder, Healthy, Mental Disorders, Mood Disorders
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: Female only
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1988 – 2000
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Borderline Personality Disorder, Major Depression
Interventions: Not listed
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Syracuse, New York

Conditions: Cirrhosis, Hepatic Encephalopathy, Fatigue, Depression
Interventions: Not listed
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 70 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia, Alcohol Use Disorder (AUD), Suicide Ideation
Interventions: Deaf CBT-TS; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Maternal Depression
Interventions: Problem Solving Education; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: Female only
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS); Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Dementia, Alzheimer's Disease, Depression
Interventions: Tele-Savvy, iPad; Behavioral · Other
Lead sponsor: Emory University; Other
Eligibility: 21 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions: Collaborative care, Usual care; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression
Interventions: Engagement and Counseling for Latinos (ECLA-F), Engagement and Counseling for Latinos (ECLA-T); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 257 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Healthy, Stress, Psychological, Depression, Posttraumatic Stress Disorders
Interventions: Not listed
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Atypical Depression
Interventions: Duloxetine; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression
Interventions: The Incredible Years Parenting Intervention, Delayed Intervention; Other
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 18 Years and older
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Major Depressive Disorder
Interventions: Coping with Depression Course (CWD) and Oh Happy Day Class (OHDC); Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 30 Years to 60 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 2
States / cities: Madison, Wisconsin • Milwaukee, Wisconsin

Conditions: Depressive Disorder, Depression, Depressive Disorder, Major, Depressive Episode, Major Depressive Disorder
Interventions: Synchronized Transcranial Magnetic Stimulation (sTMS), Sham Stimulation; Device
Lead sponsor: Wave Neuroscience; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 14
States / cities: La Jolla, California • Los Angeles, California • Stanford, California + 11 more

Conditions: Opioid Use, Stimulant Use, Depression and Anxiety Symptoms
Interventions: uMAT-R + enhanced community engagement, Original uMAT-R supplementary mHealth recovery intervention; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Respiratory Depression
Interventions: Remifentanil, Oxygen, Carbon dioxide; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Misinformation, Vaccine Hesitancy, Anxiety, Depression, COVID-19
Interventions: Attitudinal inoculation, Cognitive-behavioral therapy-informed intervention, Conventional public health messaging; Behavioral
Lead sponsor: City University of New York, School of Public Health; Other
Eligibility: 18 Years and older
Enrollment: 1,419 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression Disorders
Interventions: Kandoo; Device
Lead sponsor: Child Mind Institute; Other
Eligibility: 13 Years to 25 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression
Interventions: Imipramine Pamoate; Drug
Lead sponsor: Roxane Laboratories; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Gastrointestinal Cancer, Depression, Anxiety
Interventions: Ketamine; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

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A Closed-loop Assessment and Treatment Platform for Unipolar Depression and Anxiety

The Families and Middle School Success Project

IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL)

African American Families Fighting Parental Cancer Together

The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders

Event Related Potentials in Borderline Personality Disorder and Major Depression

Factors Associated With End Stage Liver Disease

Deaf CBT-TS to Reduce Suicide Risk

Supporting the Well Being of Families of Young Children With Autism Spectrum Disorders

Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as Adjuvant Treatment for Depression

Distance Savvy: Testing Tele-Savvy, a Distance Dementia Family Caregiver Education Program

A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients

Comparative Effectiveness Research for Eliminating Disparities

Study of Physical Health for Women With Posttraumatic Stress or Depression

A Pilot Study Assessing Duloxetine's Efficacy in Atypical Depression

Enhancing Parenting for Depressed Caregivers

African American Depression Intervention Trial (AADI)

Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder

Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City

Predictors of Opioid-Induced Respiratory Depression (OIRD)

Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression

The Use of SmartPhone App (Kandoo) to Enhance Efficacy of Brief Behavioral Activation in Reducing Mood Disorder Symptoms

Bioequivalency Study of Imipramine Pamoate 75 mg Capsules Under Fasted Conditions

Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers