Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 7:00 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1297–1320 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Hot Flashes
Interventions: melatonin 0.5 mg; Drug
Lead sponsor: Scripps Health; Other
Eligibility: 50 Years to 70 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Depression, Postpartum
Interventions: SAGE-217, Placebo; Drug
Lead sponsor: Biogen; Industry
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 68
States / cities: Scottsdale, Arizona • Bentonville, Arkansas • Anaheim, California + 62 more

Conditions: Posttraumatic Stress Disorder, Depression
Interventions: Self-Help Cognitive Processing Therapy, Women Veterans Network (WoVeN), Treatment as Usual; Behavioral · Other
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mental Health Wellness 1, Stress, Psychological, Depression, Anxiety
Interventions: Heartfulness Meditation; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 20 Years to 70 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Major Depressive Disorder
Interventions: ALKS 5461, Placebo; Drug
Lead sponsor: Alkermes, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 447 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 50
States / cities: Little Rock, Arkansas • Bellflower, California • Beverly Hills, California + 45 more

Conditions: Treatment Resistant Depression
Interventions: Olanzapine and Fluoxetine combination (OFC), Fluoxetine; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 892 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 36
States / cities: Pasadena, California • Sherman Oaks, California • Wildomar, California + 33 more

Conditions: Depressive Disorder, Bipolar Disorder, Schizoaffective Disorder
Interventions: Nonconvulsive electrotherapy; Device
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Chronic Pain, Depression, PTSD, Injuries, Illness, Chronic, Physical Disability
Interventions: Resilience and Well-Being Program; Behavioral
Lead sponsor: VA Puget Sound Health Care System; Federal
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Onychophagia
Interventions: N-Acetylcysteine (NAC), Placebo; Drug · Other
Lead sponsor: Kevin Gray, MD; Other
Eligibility: 18 Years to 30 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Depression
Interventions: Escitalopram, Placebo, IL-2; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Older Cancer Patients
Interventions: Patient Interviews, newly developed questionnaire, Pilot Testing the Draft Measure; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 70 Years and older
Enrollment: 329 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression, Sleep, Stress, Anxiety, Mood Disorders
Interventions: Probiotic; Dietary Supplement
Lead sponsor: Lindenwood University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Saint Charles, Missouri

Conditions: Anhedonia, Depression
Interventions: Family Promoting Positive Emotions, Psychoeducation; Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 8 Years to 12 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Myocardial Infarction
Interventions: Ellipsis Health Voice Application; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Head and Neck Neoplasms, Fibrosis, Lymphedema, Biomarkers, Polymorphism, Genetic, Depression
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Anxiety, Loneliness, Depression, Alcohol Use Disorder, Utilization, Health Care
Interventions: Shared Medical Visit; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Pediatric Cancer, Sickle Cell Disease, Quality of Life, Depressive Symptoms, Coping Skills
Interventions: FOCUS; Behavioral
Lead sponsor: Georgia State University; Other
Eligibility: 12 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Depression - Major Depressive Disorder, Anxiety, Stress
Interventions: Digital Physical Activity; Behavioral
Lead sponsor: Auburn University; Other
Eligibility: 19 Years to 40 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Auburn, Alabama

Conditions: Pelvic Pain, Depression
Interventions: Interpersonal Therapy for Pain (IPT-P), Enhanced Support and Connection to Counseling; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Bipolar Depression
Interventions: Probiotic Supplement, Inert Compound; Biological
Lead sponsor: Sheppard Pratt Health System; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Towson, Maryland

Conditions: Treatment Resistant Depression
Interventions: Genotyping assays; Genetic
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Attention Training, Symptoms, Cognitive, Symptoms, Affective, Symptoms, Behavioral
Interventions: attention training intervention 1, attention training intervention 2, attention training intervention 3; Behavioral
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 55 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Anxiety Disorders, Depression, Electronic Media
Interventions: Electronic Media Enhanced, Treatment as Usual; Behavioral
Lead sponsor: Mclean Hospital; Other
Eligibility: 14 Years to 85 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Obesity, Gastric Emptying, Anxiety, Depression, Panic Disorder
Interventions: Not listed
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Charleston, South Carolina

Search by objective public record fields.

Melatonin Effects on Luteinizing Hormone

A Study to Evaluate the Efficacy and Safety of SAGE-217 in Participants With Severe Postpartum Depression (PPD)

Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

Heartfulness Meditation to Improve Resilience Among Health Care Students: A 90 Day Program

A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - the FORWARD-3 Study

A Study in Relapse Prevention of Treatment-Resistant Depression

Nonconvulsive Electrotherapy: a Proof-of-concept Trial

Resilience and Well-Being Pilot Study

Use of N-Acetylcysteine (NAC) in Fingernail Biting

Effectiveness of Escitalopram in Preventing or Reducing Depressive Symptoms in People Receiving Interleukin-2 Treatment

Identifying and Measuring Depression in Older Cancer Patients

Probiotic Administration on Mood

Prevention of Anhedonia in Children

Voice Analysis Technology to Detect and Manage Depression and Anxiety in Cardiac Rehabilitation

The Fibrosis-Lymphedema Continuum in Head and Neck Cancer

Loneliness and Health Outcomes in the High Need Population

FOCUS for Pediatric Sickle Cell Disease and Cancer

Digital Intervention for Physical Activity

Psychosocial Treatment for Women With Depression and Pain

Probiotics to Prevent Relapse After Hospitalization for Bipolar Depression

Pharmacogenomics for Antidepressant Guidance and Education

Effects of Attention Training Interventions on Depression

Electronic Media and Its Application in Psychotherapy

Investigation of Neuro-hormonal Mechanisms of Hunger, Fullness and Obesity.