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ClinicalTrials.gov public records Last synced Nov 7, 2026, 7:39 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1321–1344 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Depression, Anxiety, Suicidal Ideation, Substance Use
Interventions: Knowing Who You Are (Becoming): Cultural Identity Intervention; Behavioral
Lead sponsor: University of Alaska Anchorage; Other
Eligibility: 18 Years to 100 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Anchorage, Alaska

Conditions: Respiratory Depression, Elective Surgery
Interventions: Verbal prompt, Skin Stimulus; Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 21 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Depression, Treatment Resistant Depression, Major Depressive Disorder, Depressive Disorder
Interventions: Medi-TBS; Combination Product
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Postpartum Depression
Interventions: Prenatal Yoga to Prevent Postpartum Depression (PRY-D) intervention, Treatment as Usual (TAU); Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Sarcoidosis, Fatigue, Depression, Anxiety, Mental Health
Interventions: Virtual Mindfulness Based Stress Reduction Group, Virtual sarcoidosis support group; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Breastfeeding, Exclusive, Mother-Infant Interaction, Postpartum Depression
Interventions: Babywearing; Behavioral
Lead sponsor: Nurturely; Other
Eligibility: 18 Years and older · Female only
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Diego, California

Conditions: Major Depression
Interventions: Bupropion XL, Escitalopram; Drug
Lead sponsor: Emory University; Other
Eligibility: 25 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Obesity, Depression, Diabetes, Hypertension, Hypercholesterolemia
Interventions: Holistic health; Behavioral
Lead sponsor: Duke Clergy Health Initiative; Other
Eligibility: 18 Years and older
Enrollment: 1,114 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Depressive Disorder, Major, Major Depressive Disorder (MDD)
Interventions: Paroxetine CR; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 60 Years and older
Enrollment: 560 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 46
States / cities: Little Rock, Arkansas • Anaheim, California • Beverly Hills, California + 40 more

Conditions: Depression, Unipolar
Interventions: Intravenous Ketamine; Drug
Lead sponsor: Jay Fournier; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Depression, Unipolar, Depression, Bipolar, Suicidal Ideation
Interventions: Ketamine hydrochloride injection, Midazolam injection; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Bipolar Depression
Interventions: Exercise Session, Ibuprofen 800 mg, Rest, Placebo; Other · Drug
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Major Depressive Disorder
Interventions: SHX-001 Active low dose, Placebo, SHX-001 Active High dose; Drug
Lead sponsor: Shenox Pharmaceuticals, LLC; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 3
States / cities: Gaithersburg, Maryland • Boston, Massachusetts • Dayton, Ohio

Conditions: Bipolar Disorder, Bipolar Depression
Interventions: N-acetylcysteine, Minocycline, Placebo; Dietary Supplement · Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Child Abuse, Sexual
Interventions: Trauma focused cognitive behavioral therapy (TF-CBT), Brief abuse-focused treatment, Brief coping skills treatment, Extended abuse-focused treatment, Extended coping skills treatment; Behavioral
Lead sponsor: Rowan University; Other
Eligibility: 4 Years to 11 Years
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 1
States / cities: Stratford, New Jersey

Conditions: Depression
Interventions: EVT 101, Placebo; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 14
States / cities: Oceanside, California • San Diego, California • Tampa, Florida + 11 more

Conditions: Sleep, Multiple Myeloma
Interventions: Mindfulness Awareness Practices for Insomnia, Sleep Health Information; Behavioral
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Anxiety, Depression, Anxiety Depression, Depression, Anxiety
Interventions: NeuroGlove; Device
Lead sponsor: NeuroGlove LLC; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Depression - Major Depressive Disorder
Interventions: Transcranial Electrical Stimulation (TES); Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 40 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Cancer in Remission (Any Type or Stage), Depression, Anxiety
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS); Device
Lead sponsor: Northwestern University; Other
Eligibility: 22 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depression
Interventions: Electroconvulsive Therapy; Procedure
Lead sponsor: University of Medicine and Dentistry of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 230 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 4
States / cities: Rochester, Minnesota • Newark, New Jersey • Glen Oaks, New York + 1 more

Conditions: Depression
Interventions: Fluoxetine; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 7 Years to 18 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2005
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
Interventions: Stepped Care Management; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 14 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Post Operative Delirium, Cognitive Impairment, Vagus Nerve Stimulation, Depression
Interventions: Transcutaneous vagal nerve stimulation, Sham (No Treatment); Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

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Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health

Testing of the Apnea Prevention Device

Mindfulness Engaged Neurostimulation for Depression

Prenatal Yoga to Prevent Postpartum Depression

Virtual Patient Groups for Sarcoidosis Associated Fatigue

Proyecto BEBE: The Effect of Babywearing Education on Breastfeeding Exclusivity

Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits

Study of a Holistic Health Program for United Methodist Clergy

Depression Study In Elderly Patients

Repeated Neurocognitive Measurements in Depressed Patients

IM Ketamine vs Midazolam for Suicidal ER Patients

Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression

Ketamine for Major Depressive Disorder

A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression

Optimal Treatment Strategies for Sexually Abused Children

Safety and Efficacy of EVT 101 in Treatment-Resistant Depression

Effect of Sleep Quality on Hematopoietic Cell Transplant Patient Outcomes

NeuroGlove Anxiety and Depression Study

Enhancing Slow Wave Sleep in Depression

Repetitive Transcranial Magnetic Stimulation in Cancer Patients With Depression and Anxiety

Comparison of Three Electroconvulsive Therapy (ECT) Techniques for the Treatment of Major Depression

Determining Optimal Continuation Treatment Duration for Depressed Children and Adolescents

Trauma Survivors Outcomes and Support Study IV

Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression