Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 8:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1345–1368 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Depression
Interventions: Transcranial Magnetic Stimulation; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 266 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: White River Junction, Vermont

Conditions: Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
Interventions: Real LED Treatment, Sham LED Treatment; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 38 Years to 65 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: San Francisco, California • Boston, Massachusetts

Conditions: HIV Infections
Interventions: FITT: Family Intervention - Telephone Tracking; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2004
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions: Hyperbaric Oxygen Therapy (HBOT); Drug
Lead sponsor: Summit Hyperbarics and Wellness; Other
Eligibility: 18 Years to 75 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boise, Idaho

Conditions: Postpartum Depression, Preterm Labor
Interventions: Mindfulness-based intervention (with a focus on self-compassion; MBSC), Vitamin D; Behavioral · Dietary Supplement
Lead sponsor: University of Idaho; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Coeur d'Alene, Idaho

Conditions: Depression, Anxiety, Mental Disorders
Interventions: Thirty-Second Mindfulness Practice, Three-Minute Mindfulness Practice; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Seasonal Affective Disorder
Interventions: Blue Light Box 467 nm, Red Light Box 657 nm; Device
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression
Interventions: Zolpidem, Placebo; Drug · Other
Lead sponsor: Mclean Hospital; Other
Eligibility: 21 Years to 40 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Traumatic Brain Injury (TBI) Patients
Interventions: Transcutaneous vagus nerve stimulation for attention in veterans with TBI, Soterix Medical Vagus Nerve Stimulation mini-CT; Other · Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 25 Years to 64 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cognitive Function, Depression in Old Age
Interventions: Physical exercise (PE) training and computer-based brain (CBB); Behavioral
Lead sponsor: Yale University; Other
Eligibility: 65 Years and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Depression, Anxiety, Major Depression
Interventions: Psychoeducational course; Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Depression, Depressive Disorder, Major Depressive Disorder, Treatment Resistant Depression
Interventions: Aspirin 325mg, Placebo Oral Tablet; Drug
Lead sponsor: Jessica Harder; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depressive Disorder, Low Mood
Interventions: positive feedback; Behavioral
Lead sponsor: Bard College; Other
Eligibility: 18 Years to 34 Years
Enrollment: 171 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Annandale-on-Hudson, New York

Conditions: Health Behavior, Quality of Life, Aging
Interventions: Not listed
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 110 Years
Enrollment: 10,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Depression, Anxiety, Generalized Anxiety Disorder, Depressive Disorder, Major Depressive Disorder, Cancer
Interventions: DNA-guided choice of therapy, Clinical management; Diagnostic Test · Other
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Adjustment Disorder, Anxiety Disorder, Depression, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Cancer
Interventions: Questionnaire Administration, Virtual Reality (VR) Intervention; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 90 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Depression, Chronic Pain, Substance Abuse
Interventions: co-administration of TMS and infused ketamine; Other
Lead sponsor: The Neuroscience Center, LLC; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Deerfield, Illinois

Conditions: Depressive Disorder, Major, Menopause
Interventions: Estrogen; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2004
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Systemic Lupus Erythematosus, Depression
Interventions: XCSITE100 Stimulator - Individualized theta-tACS, XCSITE100 Stimulator - Individualized alpha-tACS, XCSITE100 Stimulator - Active Sham; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Dementia, Agitation, Depressive Symptoms
Interventions: Feasibility study of music-based mobile app; Behavioral
Lead sponsor: Autotune Me LLC; Other
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Depression, Teen
Interventions: W-GenZD; Device
Lead sponsor: Woebot Health; Industry
Eligibility: 16 Years to 17 Years
Enrollment: 246 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Impulsivity, Active Suicidal Ideation, Depression
Interventions: placebo, Riperidone; Other · Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 64 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Adjustment Disorder
Interventions: RE104 for Injection; Drug
Lead sponsor: Reunion Neuroscience Inc; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 32
States / cities: Birmingham, Alabama • Tucson, Arizona • San Diego, California + 28 more

Conditions: Psychological Stress, Anxiety, Depression
Interventions: Stress Free Now online program, Group support session; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

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Assessing an EEG Biomarker of Response to TMS for Major Depression

Scalp Application of LED Therapy to Improve Thinking and Memory in Veterans With Gulf War Illness

Effectiveness of a Telephone Intervention Program in Improving Depression, Coping, and Family Functioning in HIV-Infected Individuals and Caregivers

HBOT Effects on First Responders' Cognition and Well-Being

Maternal Stress on Human Milk and Infant Outcomes

The Feasibility and Efficacy of an Extremely Brief Mindfulness Practice

Research Study of Treatment for Winter Depression With Different Colors of Light

Proton MRS Study of SSRI-Zolpidem Interactions

Transcutaneous Vagus Nerve Stimulation for Attention and Memory

Computer Presented and Physical Exercises to Maintain Cognitive Function and Emotional Health in Older Adults

Mindfulness and Lifestyle Interventions for Depression and Anxiety: A Pilot Study

Salicylic Augmentation in Depression

Positive Feedback vs. No-Feedback Games for Behavioral Change

The Lake Nona Life Project

Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients

Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment

Neuromodulation to Facilitate the Effect of Ketamine

Estrogen and Perimenopausal Depression

LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE

A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)

Digital Therapeutic vs Psychoeducation for Management of Mild to Moderate Depression in Adolescents

Impulsivity and Thought Process Disorder in Patients With Active Suicidal Ideation and Depression

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

Stress Free Now, a Mind-body Reduction Program for Nurses