Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 8:35 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1393–1416 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Sexual Dysfunction, Depression
Interventions: sildenafil; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Chronic Pain, Depression
Interventions: RELIEF; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 50 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 3
States / cities: New York, New York

Conditions: Depression, Insomnia, Suicide
Interventions: Behavioral Activation for Depression, Cognitive Behavior Therapy for Insomnia, Collaborative Assessment and Management of Suicidality, Care-as-Usual Psychotherapy; Behavioral
Lead sponsor: Evidence-Based Practice Institute, Seattle, WA; Industry
Eligibility: 18 Years and older
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression
Interventions: Escitalopram, Bupropion XL; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 75 Years
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Major Depression
Interventions: Duloxetine; Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Depression
Interventions: Org 24448, Placebo; Drug
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 21 Years to 70 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 2
States / cities: Bethesda, Maryland • New York, New York

Conditions: Osteoarthritis (OA)
Interventions: Sit 'N' Fit Chair Yoga (SNFCY), Health Education Program (HEP); Behavioral
Lead sponsor: Florida Atlantic University; Other
Eligibility: 65 Years and older
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Deerfield Beach, Florida • Pembroke Pines, Florida

Conditions: Major Depressive Disorder
Interventions: Cognitive Behavior Therapy (CBT), Nonspecific Supportive Therapy (PBO); Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Depressive Disorder, Major
Interventions: Cognitive Therapy (CT) for depression, Cognitive Therapy (CT) for depression + Memory Support; Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Severe Asthma, Moderate or Severe Major Depressive Disorder
Interventions: Placebo, Escitalopram; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Asthma, Depression, Anxiety
Interventions: Asthma self-management; Behavioral
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 85 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Rheumatoid Arthritis, Systemic Lupus Erythematosus, Arthritis
Interventions: Not listed
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2018
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Depression, Parkinson's Disease
Interventions: Cognitive-behavioral therapy (CBT); Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: Not listed
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depressive Symptoms, Anxiety States, Neurotic
Interventions: Continuous Client Feedback, Continuous Self Feedback; Behavioral
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years to 64 Years
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Depression, Substance Use
Interventions: ACT HEALTHY, Nondirective Therapy (NDT); Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 65 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • College Park, Maryland

Conditions: Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship, Parent-Child Relationship, Parent-Child Relations, Stress Disorder, Post Traumatic, PTSD, Parenting, Child Behavior, Emotional Regulation, Emotion Regulation
Interventions: Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU); Behavioral
Lead sponsor: New York University; Other
Eligibility: 18 Years and older
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 4
States / cities: Colorado Springs, Colorado • Silver Spring, Maryland • Lawton, Oklahoma + 1 more

Conditions: Suicidal Behaviors, Suicide Ideation, Depression/Anxiety
Interventions: Aviva; Behavioral
Lead sponsor: University of Memphis; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Colorado Springs, Colorado

Conditions: Depression in Old Age
Interventions: Endotoxin, Placebo; Biological
Lead sponsor: Michael Irwin, MD; Other
Eligibility: 60 Years to 80 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depressive Disorder
Interventions: memantine, Placebo; Drug
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 85 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Depression Mild, Depression Moderate
Interventions: Yoga practice, Education; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression
Interventions: AZD6765; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 5
States / cities: Glendale, California • Hartford, Connecticut • New Haven, Connecticut + 2 more

Conditions: Mental Health Issue
Interventions: QActual; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Treatment Resistant Depression, Electroconvulsive Therapy, ECT, Ketamine, Psychiatric Disorder, Depression, Major Depressive Disorder, Major Depressive Episode, Unipolar Depression
Interventions: electroconvulsive therapy (ECT), Ketamine; Procedure · Drug
Lead sponsor: Bo Hu; Other
Eligibility: 21 Years to 75 Years
Enrollment: 403 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 5
States / cities: New Haven, Connecticut • Baltimore, Maryland • New York, New York + 2 more

Conditions: Major Depressive Disorder With Psychotic Features
Interventions: Quetiapine, escitalopram, Sertraline, Citalopram; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Study of Sildenafil for Treatment of SSRI-Antidepressant Sexual Dysfunction in Women

A Behavioral Intervention for Depression and Chronic Pain in Primary Care

PracticeGround: Transforming Training and Delivery of Mental Health EBPs

Personalized Indicators for Predicting Response to SSRI Treatment in Major Depression (The PRISE-MD Study)

Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine

Org 24448 to Treat Major Depression

Effect of Chair Yoga on Elders With Osteoarthritis

Mechanisms of Emotion Regulation Underlying Successful CBT in Depression

Can the Memory Support Intervention Improve Depression Outcome Following Cognitive Therapy?

Treatment of Outpatients With Severe Asthma and Moderate or Severe Major Depressive Disorder

Trial of Asthma Self-Management Education in Patients With Depressive Symptoms

Health Beliefs and Health Behaviors Among Minorities With Rheumatic Diseases

Telehealth Psychotherapy for Depression in Parkinson's Disease

Using the PHQ-9 and GAD-7 as Feedback Instruments in Brief Psychotherapy

Behavioral Depression Treatment for African American HIV-infected Substance Users

Parenting-STAIR Modular for Military Fathers and OCONUS Families

Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors

Sleep and Healthy Aging Research for Depression (SHARE-D) Study

Memantine Augmentation of Antidepressants

Treating Major Depression With Yoga Mono-therapy

AZD6765 for Treatment Resistant Depression

Effect of a Mental Wellness App on the Mental Wellness of Medical and Nurse Anesthesia Students

ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)

Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms