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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:11 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1465–1488 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder NOS, Chronic Pain
Interventions: Mindfulness Based Cognitive Therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depression, Posttraumatic Stress Disorders, Anxiety Disorders
Interventions: telephone care; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 324 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: White River Junction, Vermont

Conditions: Childhood Depression
Interventions: Family-Focused Treatment for Childhood-Depression (FFT-CD); Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 7 Years to 12 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Boston, Massachusetts • Charlestown, Massachusetts

Conditions: Retina--Diseases, Retinal Detachment, Retinal Degeneration
Interventions: Schocket scleral depressor, Cotton tipped applicator; Device
Lead sponsor: New York City Health and Hospitals Corporation; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Anxiety, Depression, Psychological Stress, Psychological Distress, Well-being
Interventions: Healthy Minds Program Foundations Training; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 698 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Obesity, Depression
Interventions: I-CARE2; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Depressive Symptoms, Major Depressive Disorder, Recurrent, in Remission
Interventions: Be Mindful; Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years to 65 Years
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder, Suicidal Ideation
Interventions: Collaborative care Plus; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 12
States / cities: Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 3 more

Conditions: Knee Osteoarthritis, Pain, Depression
Interventions: Exercise, Duloxetine, Placebo, PT referral; Behavioral · Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years and older
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2032
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depression, Pregnancy Related, Antenatal Depression, Depression, Postpartum
Interventions: MMB for Moms; Behavioral
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Depression, Stress Disorders, Post-Traumatic
Interventions: Resilience Training for Veterans (REST-V), Usual resources; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 2
States / cities: Syracuse, New York • Durham, North Carolina

Conditions: Major Depression, Mental Health
Interventions: Provigil; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 4
States / cities: Stanford, California • Atlanta, Georgia • New York, New York + 1 more

Conditions: Stress (Psychology), Resilience, Psychological, Anxiety, Depressive Symptoms, Well-being, Sleep Quality
Interventions: Wearable ring with continuous biometric monitoring, AI health coaching application, Osteopathic manipulative treatment (OMT); Device · Behavioral · Other
Lead sponsor: Touro University, California; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Vallejo, California

Conditions: Depression
Interventions: Cognitive factors, Behavioral factors, Increase engagement of pleasant events; Behavioral
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Anxiety, PTSD, Depression
Interventions: H.O.O.V.E.S. Healing Intensives; Behavioral
Lead sponsor: VA Salt Lake City Health Care System; Federal
Eligibility: 18 Years to 120 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Depression
Interventions: BioKefir, Non-fermented milk; Dietary Supplement
Lead sponsor: Rush University Medical Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depression and Burden in Caregivers
Interventions: Mindoula, DANA; Behavioral · Device
Lead sponsor: AnthroTronix, Inc.; Industry
Eligibility: 45 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Silver Spring, Maryland

Conditions: Major Depressive Disorder
Interventions: Agomelatine, paroxetine, placebo; Drug
Lead sponsor: Novartis; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 501 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2007
U.S. locations: 46
States / cities: Phoenix, Arizona • National City, California • Orange, California + 40 more

Conditions: Stress
Interventions: Authentic Connections, Protected time; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 3
States / cities: Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota

Conditions: Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk, Depression, Depression, Postpartum, Perinatal Depression, Anxiety, Anxiety in Pregnancy, Stress, Psychological, Racism, Discrimination, Racial, Inflammation
Interventions: MWSH plus Candlelit Care, MWSH; Device
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Diabetes, Myocardial Infarction, Stroke, Kidney Diseases, Bone Diseases, Dyslipidemia
Interventions: Lifestyle Intervention, Diabetes Support and Education; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 55 Years to 76 Years
Enrollment: 5,145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2020
U.S. locations: 18
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 14 more

Conditions: Diabetes, Depression, Physical Activity
Interventions: DIAMANTE Adaptive, DIAMANTE Static; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 75 Years
Enrollment: 226 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Chronic Pain, Depression
Interventions: Relief-Hybrid; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 50 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 4
States / cities: New York, New York • White Plains, New York

Conditions: Postpartum Depression (PPD)
Interventions: Light therapy; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Search by objective public record fields.

Mindfulness Based Cognitive Therapy for Chronic Pain and Comorbid Unipolar Depression

Telephone Care as a Substitute for Routine Psychiatric Medication

Neural Mechanisms of Family-Focused Treatment for Youth Depression

Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations

COVID-19 and the Healthy Minds Program for Educators

Engaging Self-regulation Targets to Improve Mood and Weight and Understand Mechanism in Depressed and Obese Adults

The Effects of the Be Mindful Intervention in Previously Depressed Individuals Experiencing Subclinical Symptoms

Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses

Duloxetine and aeRobic Exercise to Improve Function in VEterans With Knee Osteoarthritis (DRIVE)

How Does Mindful Mood Balance for Moms Work?

Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms

Provigil in Conjunction With SSRIs for the Treatment of Mild or Moderate Depression With Attendant Symptoms of Sleepiness and Fatigue.

High-Tech, High-Touch

Brief Inpatient Psychotherapy for Depression

Evaluation of the H.O.O.V.E.S. Healing Intensives Program

Fermented Milk Product With Probiotic and Its Impact on Mood of Patients With Treatment Resistant Depression

Health-eBrain Study

A Placebo- and Paroxetine-controlled Study of the Efficacy, Safety and Tolerability of Agomelatine (25 or 50 mg) in the Treatment of Major Depressive Disorder (MDD)

Authentic Connections for Nurse Leaders

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

Look AHEAD: Action for Health in Diabetes

Diabetes and Depression Text Messaging Intervention

A Behavioral Intervention for Depression and Chronic Pain in Primary Care (Relief-Hybrid)

Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression