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Showing 1–24 of 1,270 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Depression, Anxiety Clear all
Completed Phase 1 Interventional Results available

Healthy Minds Program App Dosage

NCT05229406
View directory record Official record
Conditions
Depression, Anxiety, Psychological Distress
Interventions
HMP app
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 20, 2026, 6:41 PM EDT
Recruiting Phase 2Phase 3 Interventional

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

NCT05474846
View directory record Official record
Conditions
Sleep, Fatigue, Anxiety, Cancer, Depression
Interventions
Melatonin, Placebo for Melatonin, Methylphenidate
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders

NCT01243606
View directory record Official record
Conditions
Anxiety Disorders, Mood Disorders
Interventions
Single Diagnosis Treatment Protocol, Unified Protocol (UP)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Jul 20, 2026, 6:41 PM EDT
Suspended Not applicable Interventional

Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)

NCT07102212
View directory record Official record
Conditions
Lung Cancer, Breast Cancer, Prostate Cancer, Multiple Myeloma, Melanoma
Interventions
mHealth Intervention
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Jul 20, 2026, 6:41 PM EDT
Suspended Not applicable Interventional

Mobile Virtual Positive Experiences for Anhedonia

NCT03715400
View directory record Official record
Conditions
Anhedonia, Virtual Reality, Depression, Mood Disorders, Stress, Anxiety
Interventions
Positive Virtual Reality Training
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Mental Health Support for Transgender and Gender-expansive Individuals

NCT06229132
View directory record Official record
Conditions
Transgender, Depression, Anxiety, Suicidality, HIV
Interventions
LGBTQ-affirmative CBT for transgender individuals
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of SKY Breath Meditation on Health and Well-being

NCT05523414
View directory record Official record
Conditions
Stress, Stress, Psychological, Stress, Physiological, Anxiety, Mental Well Being, Happiness, Resilience
Interventions
SKY
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 99 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 20, 2026, 6:41 PM EDT
Terminated Phase 2 Interventional

Risperidone vs. Paroxetine for Panic Attacks

NCT00206765
View directory record Official record
Conditions
Major Depressive Disorder With Panic Attacks, Panic Disorder
Interventions
Risperidone, Paroxetine
Drug
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
21 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2012 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings

NCT00974402
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Evaluation of a Crowd-Powered Web Platform for Depression and Anxiety

NCT04226742
View directory record Official record
Conditions
Depression, Anxiety
Interventions
ADAPT Platform (Treatment), ADAPT Comparison (Control)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Targeting HIV Retention and Improved Viral Load Through Engagement ('THRIVE')

NCT04481373
View directory record Official record
Conditions
Human Immunodeficiency Virus, Depression, Anxiety
Interventions
THRIVE, Treatment as Usual
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 20, 2026, 6:41 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

NCT06624137
View directory record Official record
Conditions
OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
Interventions
Serotonergic Psychedelic, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Hamden, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 20, 2026, 6:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Transforming Adolescent Mental Health Through Accessible, Scalable, Technology-supported Small-group Instruction

NCT05860257
View directory record Official record
Conditions
Anxiety Depression, Suicidal Ideation
Interventions
PeerLearning.net
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
14 Years to 65 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Tempe, Arizona • Eugene, Oregon • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Compassion Training and Mindfulness Training for Social Well-Being and Mental Health

NCT05227794
View directory record Official record
Conditions
Anxiety, Depression, Stress, Burnout, Emotion Regulation, Social Acceptance, Loneliness, Compassion
Interventions
Compassion Cultivation Training (CCT), Mindfulness-Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Jul 20, 2026, 6:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mechanisms of Anxiety and Depression Study

NCT03135756
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Not listed
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years to 55 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Los Altos, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated May 10, 2018 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Affect Treatment for Depression and Anxiety

NCT05203861
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Positive Affect Treatment, Negative Affect Treatment
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Jul 20, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Creative Arts Program to Reduce Burnout in Healthcare Professionals

NCT04276922
View directory record Official record
Conditions
Burn-Out Syndrome, Post-Traumatic Stress Disorder, Depression, Anxiety
Interventions
Visual Arts, Music, Dance/Movement, Writing/Poetry, Control
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 85 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Care Outcomes for Chiropractic Outpatient Veterans

NCT03254719
View directory record Official record
Conditions
Low Back Pain, PTSD, Depression, Anxiety
Interventions
Study assessments
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Coralville, Iowa • Davenport, Iowa • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated May 17, 2020 · Synced Jul 20, 2026, 6:41 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

African American Families Fighting Parental Cancer Together

NCT03567330
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Parental Stress
Interventions
Family-based attachment-focused intervention, Psychoeducation
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
11 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
2
States / cities
Newark, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring the Efficacy of Treatments for Anxiety and Depression Among College Students

NCT06013930
View directory record Official record
Conditions
Anxiety, Depression
Interventions
External Qigong, Mindfulness Meditation, Psychoeducation
Behavioral · Other
Lead sponsor
University of South Dakota
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Mental Health First Aid for College Students

NCT02021344
View directory record Official record
Conditions
Depression, Anxiety, Suicidal Ideation, Eating Disorders
Interventions
Mental Health First Aid
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
2,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 26, 2013 · Synced Jul 20, 2026, 6:41 PM EDT
Enrolling by invitation Phase 2 Interventional

An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)

NCT07161700
View directory record Official record
Conditions
Major Depressive Disorder (MDD), Major Depressive Disorder With Anxious Distress
Interventions
SPT-300
Drug
Lead sponsor
Seaport Therapeutics
Industry
Eligibility
18 Years to 66 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
14
States / cities
Chino, California • Garden Grove, California • Glendale, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 20, 2026, 6:41 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

NCT00018057
View directory record Official record
Conditions
Anxiety Disorders, Major Depressive Disorder
Interventions
Attention Bias Modification Training, Fluoxetine, Cognitive Behavioral Therapy
Behavioral · Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
8 Years to 65 Years
Enrollment
3,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2029
U.S. locations
2
States / cities
Bethesda, Maryland • College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 20, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Music Therapy Intervention to Reduce Caregiver Distress at the End of Life

NCT03322228
View directory record Official record
Conditions
Quality of Life, Stress, Anxiety, Depression
Interventions
Music Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Jul 20, 2026, 6:41 PM EDT