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ClinicalTrials.gov public records Last synced Oct 4, 2026, 1:11 PM EDT

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Showing 97–120 of 166 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression, Anxiety, PTSD Clear all
Completed No phase listed Observational Accepts healthy volunteers

Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents

NCT04783506
View directory record Official record
Conditions
Suicide and Depression
Interventions
Observational Study
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 4, 2026, 1:11 PM EDT
Recruiting Not applicable Interventional

The BEAR Program for Women With Trauma Who Have Suicidal Thoughts

NCT07346638
View directory record Official record
Conditions
Interpersonal Trauma, Depression, PTSD, Anxiety, Suicidal Ideations, Sexual Assault
Interventions
BEAR-SI
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Phase 1 Interventional

Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression

NCT00961454
View directory record Official record
Conditions
Major Depression, Anxiety Disorder, Post-Traumatic Stress Disorder, Substance Abuse Disorder
Interventions
Photobiomodulation with a super-luminous light emitting diode
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2009 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

FOCUS:Families OverComing Under Stress

NCT02992405
View directory record Official record
Conditions
Cancer, Depression, PostTraumatic Stress Disorder, Anxiety
Interventions
FOCUS Resilience Enhancement Program, Waitlist (No Study Treatment)
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
5 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Phase 3 Interventional Results available

Pharmacologic Treatment of PTSD in Sexually Abused Children

NCT00078767
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Trauma-Focused Cognitive Behavioral Therapy, Sertraline Pill, Placebo Oral Tablet
Behavioral · Drug
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
10 Years to 17 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 4, 2026, 1:11 PM EDT
Enrolling by invitation Not applicable Interventional

Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida

NCT06648928
View directory record Official record
Conditions
PTSD Symptoms, Anxiety Symptoms, Depression Symptoms, Sleep Disturbance
Interventions
Clinician Supported PTSD Coach, Self Managed PTSD Coach
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional

Adaptation and Evaluation of the KEEP Model

NCT05816421
View directory record Official record
Conditions
Depression, Anxiety, Post Traumatic Stress Disorder, Suicide and Self-harm, Externalizing Behavior
Interventions
KEEP, Non-Affinity KEEP
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
4 Years to 21 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer-led Group Intervention for Coping With Disaster

NCT03907995
View directory record Official record
Conditions
Anxiety Disorder, PTSD, Depressive Symptoms, Anger, Depressive Disorder
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional Results available

Optimizing a Mobile Mindfulness Intervention for ICU Survivors

NCT04038567
View directory record Official record
Conditions
Cardiorespiratory Failure
Interventions
Mobile mindfulness-based training
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Aurora, Colorado • Durham, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional

Arts and Movement Therapies for Trauma

NCT03515564
View directory record Official record
Conditions
PTSD, Depression, Anxiety, Stress, Trauma
Interventions
Dance/Movement Therapy, Art Therapy, Mindful Yoga
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
7 Years to 65 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans

NCT04032301
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Major Depressive Disorder
Interventions
Ketamine, Normal Saline
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional

Coherence Training for Military Personnel

NCT01599598
View directory record Official record
Conditions
Stress
Interventions
Progressive Muscle Relaxation, Coherence Advantage
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
Not listed
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2016 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Integrative, Digital Health Approach to Veteran-Centered PTSD Care

NCT06993012
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, Depression/Anxiety
Interventions
Mobile Health Stress Self Management System, Intensive Cycling Activity
Behavioral
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 4, 2026, 1:11 PM EDT
Completed No phase listed Observational

Stanford RAD-AT Study (Research on Anxiety and Depression - Anhedonia Treatment)

NCT02220309
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Pramipexole Oral Tablet
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
3
States / cities
Los Altos, California • Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 4, 2026, 1:11 PM EDT
Terminated Not applicable Interventional Results available

Effectiveness of Cognitive Processing Therapy in Pregnant Women With a History of Pregnancy Loss/Complication

NCT01277354
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Stress Disorders, Anxiety, Depression
Interventions
Cognitive Processing Therapy, Waitlist Placebo
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional Results available

Primary-Care Based Mindfulness Intervention

NCT03922581
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Major Depressive Disorder
Interventions
Mindfulness-Based Cognitive Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional

Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological Outcomes

NCT04510272
View directory record Official record
Conditions
Anxiety, Depression, PTSD
Interventions
Aloud Real-time Reading of ICU Diaries
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 4, 2026, 1:11 PM EDT
Not yet recruiting Not applicable Interventional

Deaf CBT-TS to Reduce Suicide Risk

NCT07279363
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia, Alcohol Use Disorder (AUD), Suicide Ideation
Interventions
Deaf CBT-TS
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional Results available

Supported Employment in Patient Aligned Care Teams

NCT02400736
View directory record Official record
Conditions
Mental Disorder, Substance Use Disorders, Posttraumatic Stress Disorder, Major Depressive Disorder, Anxiety Disorder
Interventions
Individual Placement and Support (IPS), Treatment as Usual Vocational Rehabilitation/Transitional Work (TUA-VR)
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness Training in U.S. Army Cohorts

NCT03310112
View directory record Official record
Conditions
Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression, Cognitive Change
Interventions
4-week MBAT, 2-week MBAT
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Sep 18, 2018 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional

Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women

NCT06646692
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Anxiety, Depression - Major Depressive Disorder
Interventions
Mindful Self Compassion, Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 4, 2026, 1:11 PM EDT
Completed Not applicable Interventional

Impact of Community-Based Biofeedback Program on Drug Use and Mental Health Among People Experiencing Homelessness

NCT05897580
View directory record Official record
Conditions
Heart Rate Variability
Interventions
Heart Rate Variability - Biofeedback (HRV-BF), Health Promotion (HP)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2023 · Synced Oct 4, 2026, 1:11 PM EDT
Recruiting Not applicable Interventional

Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans

NCT06906185
View directory record Official record
Conditions
Trauma-related Mental Health Symptoms
Interventions
Calm Moms-V, Care As Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 4, 2026, 1:11 PM EDT
Active, not recruiting Not applicable Interventional

Virtual Reality Intervention for Patients Undergoing BMT

NCT05629676
View directory record Official record
Conditions
Bone Marrow Transplant Complications
Interventions
BMT-VR
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 4, 2026, 1:11 PM EDT