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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Depression Clear all
Enrolling by invitation No phase listed Observational

Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study

NCT07222306
View directory record Official record
Conditions
PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
Interventions
1-(2-[+F]fluoroethyl)-L-tryptophan
Drug
Lead sponsor
Wayne State University
Other
Eligibility
19 Years to 69 Years
Enrollment
100 participants
Timeline
2025 – 2030
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional

Training Doctors to Support Patient Self-Care of Depression

NCT01618552
View directory record Official record
Conditions
Depression, Diabetes
Interventions
SEE IT training, Knowledge enhancement
Behavioral · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Jul 23, 2026, 4:19 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Omega 3 FA Supplements as Augmentation in the Treatment of Depression

NCT01803711
View directory record Official record
Conditions
Major Depression, Cancer, Diabetes, Cardiovascular Diseases
Interventions
Desvenlafaxine, Omega 3 Fatty acids, Placebo (for Omega 3 fatty acid supplement)
Drug · Dietary Supplement
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 26, 2017 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Phase 2 Interventional Results available

Ketamine for Depression and Suicide Risk

NCT02094898
View directory record Official record
Conditions
Depression, Suicide
Interventions
Ketamine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional

Universal Screening for Maternal Depression With the CHICA System

NCT01238614
View directory record Official record
Conditions
Maternal Depression
Interventions
CHICA PSF plus JIT, CHICA maternal depression PSF, Control
Other
Lead sponsor
Indiana University
Other
Eligibility
Female only
Enrollment
3,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 9, 2010 · Synced Jul 23, 2026, 4:19 PM EDT
Recruiting Phase 2 Interventional

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

NCT07336238
View directory record Official record
Conditions
Anxiety, Depression, Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm
Interventions
Psychotherapy, Psilocybin, Survey Administration
Behavioral · Drug · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional

S1008: Exercise, Diet, & Counseling in Improving Weight Loss in Overweight Female Breast or Colorectal Cancer Survivors

NCT01453452
View directory record Official record
Conditions
Anxiety Disorder, Breast Cancer, Cognitive/Functional Effects, Colorectal Cancer, Depression, Fatigue, Pain, Psychosocial Effects of Cancer and Its Treatment, Weight Changes
Interventions
behavioral dietary intervention, exercise intervention, counseling intervention, quality-of-life assessment
Behavioral · Other · Procedure
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
Up to 120 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
58
States / cities
Tucson, Arizona • Antioch, California • Fremont, California + 45 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional Results available

Self-guided Treatment for Adolescents Navigating Depression

NCT05462652
View directory record Official record
Conditions
Depressive Symptoms, Depression, Depressive Disorder, Depressive Episode
Interventions
Active Intervention
Device
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional

Heart Failure Caregiver Study

NCT01937936
View directory record Official record
Conditions
Stress, Depression
Interventions
Cognitive Behavioral Therapy (CBT), Health Education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Activating Messages for Enhancing Primary Care Practice (AMEP2): Effectiveness Study

NCT01144104
View directory record Official record
Conditions
Depression
Interventions
Public Service Announcement, Interactive Multi-Media Computer Program, Sleep Hygiene Video
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
25 Years to 70 Years
Enrollment
925 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
6
States / cities
Elk Grove, California • Mather, California • Sacramento, California + 1 more
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major Depression

NCT03386448
View directory record Official record
Conditions
Depression
Interventions
Scopolamine and naltrexone, placebo arm
Drug
Lead sponsor
The Taub Group
Industry
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Jul 23, 2026, 4:19 PM EDT
Active, not recruiting Not applicable Interventional

Virtual Reality in Hemodialysis to Improve Psychological Well-being

NCT05642364
View directory record Official record
Conditions
End Stage Kidney Disease, Depressive Symptoms
Interventions
Joviality(TM), Inert Virtual Reality
Behavioral · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Jul 23, 2026, 4:19 PM EDT
Withdrawn Not applicable Interventional

Intervention for Rural Cancer Patients

NCT05091593
View directory record Official record
Conditions
Depression, Quality of Life, Social Support, Sleep, Stress
Interventions
Stepped collaborative care intervention, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional Results available

Mindfulness Based Stress Reduction and Post-Stroke Cognition

NCT04302493
View directory record Official record
Conditions
Stroke, Stroke Sequelae, Depression, Cognitive Impairment
Interventions
Mindfulness Based Stress Reduction (MBSR), Stroke Support Group (SSG)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Reducing Depression in Dementia Caregivers

NCT00056316
View directory record Official record
Conditions
Depression
Interventions
Basic Education, Behavioral Skills Training: Experimental
Behavioral
Lead sponsor
University of Missouri, St. Louis
Other
Eligibility
50 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2014 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D Supplementation and Effects on Mood in Emergency Medicine Residents

NCT03739671
View directory record Official record
Conditions
Seasonal Mood Disorder
Interventions
Vitamin D, No Vitamin D
Dietary Supplement
Lead sponsor
Corewell Health South
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Phase 1Phase 2 Interventional

Cognitive Training for Depression

NCT01936506
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Cognitive Training A, Cognitive Training B
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Jul 23, 2026, 4:19 PM EDT
Completed No phase listed Observational

Acoustical Properties of Speech as Indicators of Suicidal Risk

NCT00178906
View directory record Official record
Conditions
Depression
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
25 Years to 65 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease?

NCT05980130
View directory record Official record
Conditions
Rumination, Depressive Symptoms, Blood Pressure
Interventions
Rumination-Focused Cognitive Behavior Therapy
Behavioral
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jul 23, 2026, 4:19 PM EDT
Suspended Not applicable Interventional

ORCHID: An Online Intervention for Persons With HIV (Miami)

NCT05935644
View directory record Official record
Conditions
HIV/AIDS, HPV Infection
Interventions
ORCHID
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional Results available

Testing the Feasibility of the Individualized Positive Psychosocial Intervention (IPPI)

NCT05980299
View directory record Official record
Conditions
Dementia, Depression, Behavior
Interventions
Individualized Positive Psychosocial Interaction
Behavioral
Lead sponsor
Miami University
Other
Eligibility
18 Years to 110 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
7
States / cities
Beavercreek, Ohio • Canal Fulton, Ohio • Fairborn, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Phase 2 Interventional Results available

Sunshine 2 Study for Women With Diabetes

NCT01904032
View directory record Official record
Conditions
Diabetes, Depression, Quality of Life
Interventions
Vitamin D3, Vitamin D3 comparator
Drug
Lead sponsor
Loyola University
Other
Eligibility
21 Years and older · Female only
Enrollment
265 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Jul 23, 2026, 4:19 PM EDT
Completed Not applicable Interventional

A Biobehavioral/Cognitive Treatment for Stress, Depression, and Anxiety in Patients With Stage IV Lung Cancer

NCT05342571
View directory record Official record
Conditions
Advanced Lung Carcinoma, Metastatic Lung Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
Interventions
Behavioral, Psychological or Informational Intervention, Biospecimen Collection, Electronic Health Record Review, Informational Intervention, Survey Administration
Other · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 22, 2023 · Synced Jul 23, 2026, 4:19 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

NCT05552053
View directory record Official record
Conditions
Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk, Depression, Depression, Postpartum, Perinatal Depression, Anxiety, Anxiety in Pregnancy, Stress, Psychological, Racism, Discrimination, Racial, Inflammation
Interventions
MWSH plus Candlelit Care, MWSH
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 23, 2026, 4:19 PM EDT