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ClinicalTrials.gov public records Last synced Oct 28, 2026, 5:07 AM EDT

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Showing 697–720 of 5,331 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression Clear all
Completed Not applicable Interventional

Systems of Care for New Moms: Integrating Depression Treatment

NCT01407783
View directory record Official record
Conditions
Post-partum Depression
Interventions
Problem Solving Tools (PST)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 28, 2026, 5:07 AM EDT
Not listed No phase listed Observational

Morbidity and Mortality Among Dialysis Patients After Treatment for Depression

NCT00442429
View directory record Official record
Conditions
Depression, ESRD
Interventions
Not listed
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 2, 2007 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Personalized Mind-Body Intervention (MBI) for Improving Sleep Among Women Working in Healthcare

NCT05789212
View directory record Official record
Conditions
Sleep Insufficiency
Interventions
Personalized Trial ABCCBA, Personalized Trial CBAABC
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Improving Care of Patients With Heart Failure

NCT01461681
View directory record Official record
Conditions
Depression, Pain, Dyspnea, Quality of Life
Interventions
Symptom Management Service for Heart failure
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 14, 2014 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Addressing Psychosocial Comorbidities in HIV Treatment and Prevention

NCT02696681
View directory record Official record
Conditions
Human Immunodeficiency Virus, Depression, Mental Health
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Oct 28, 2026, 5:07 AM EDT
Recruiting Not applicable Interventional

MBM and taVNS for Low Back Pain and Depressive Symptoms

NCT07415941
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
MBM, VNSM
Behavioral · Device
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Pivotal Test: WB001

NCT04576754
View directory record Official record
Conditions
Postpartum Depression
Interventions
WB001, Educational
Device
Lead sponsor
Woebot Health
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Digital Therapeutic vs Psychoeducation for Management of Mild to Moderate Depression in Adolescents

NCT04985331
View directory record Official record
Conditions
Depression, Teen
Interventions
W-GenZD
Device
Lead sponsor
Woebot Health
Industry
Eligibility
16 Years to 17 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Oct 28, 2026, 5:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Positive Affect Treatment for Adolescents With Early Life Adversity

NCT06273137
View directory record Official record
Conditions
Depression
Interventions
Positive affect treatment, Supportive psychotherapy (SUP)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
12 Years to 16 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 28, 2026, 5:07 AM EDT
Terminated Phase 1 Interventional

The Role of HNKs in the Antidepressant Effect of Ketamine

NCT03977675
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Ketamine
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 22, 2021 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD

NCT02874131
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions
Behavioral Activation, Cognitive Processing Therapy
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Phase 2 Interventional Results available

Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients

NCT02935595
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Ketamine
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Oct 28, 2026, 5:07 AM EDT
Withdrawn Not applicable Interventional

Auditory Stimulation for Insomnia and Depression

NCT07553364
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Insomnia
Interventions
Alpha phase-locked auditory stimulation, Sham Stimulation
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
20 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional Results available

Ketamine Infusion for Treatment-resistant Major Depressive Disorder

NCT01582945
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Ketamine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Mindfulness Training for Adults With History of Depression

NCT05347719
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
MBCT Intervention
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Clemson, South Carolina • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional

The RAFT ECT Study

NCT05402657
View directory record Official record
Conditions
Major Depressive Episode
Interventions
Frontoparietal Ultrabrief Right Unilateral (UBRUL-FP) electroconvulsive therapy, Temporoparietal Ultrabrief Right Unilateral (UBRUL-TP) electroconvulsive therapy
Procedure
Lead sponsor
The George Institute
Other
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Atlanta, Georgia • Augusta, Georgia • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Cognitive Training to Enhance VA Work Program Outcomes

NCT00829400
View directory record Official record
Conditions
Mental Illness, Schizophrenia, Depression, PTSD, Bipolar Disorder
Interventions
Cognitive Remediation, Nintendo Brain Age
Behavioral
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Oct 28, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Chronobiology and Depression: Circadian Analytics as a Biomarker for Depressive Subtypes

NCT03538275
View directory record Official record
Conditions
Depression, Bipolar, Depression, Unipolar, Healthy
Interventions
Monitoring test
Other
Lead sponsor
Medibio Limited
Industry
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 28, 2026, 5:07 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study

NCT03523767
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
S.typhi Injection, Normal Saline Injection
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Oct 28, 2026, 5:07 AM EDT
Completed No phase listed Observational

A Longitudinal Study of Inflammatory Pathways in Depression

NCT04159207
View directory record Official record
Conditions
Major Depressive Disorder, Suicide, Attempted
Interventions
Not listed
Lead sponsor
Van Andel Research Institute
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional Results available

Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)

NCT02248675
View directory record Official record
Conditions
Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
Interventions
CBT-I, TAU
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2017 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health

NCT04561544
View directory record Official record
Conditions
Depression, Anxiety, Suicidal Ideation, Substance Use
Interventions
Knowing Who You Are (Becoming): Cultural Identity Intervention
Behavioral
Lead sponsor
University of Alaska Anchorage
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Oct 28, 2026, 5:07 AM EDT
Completed Not applicable Interventional Results available

Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans

NCT01253044
View directory record Official record
Conditions
Distress, Anxiety, Depression, Postconcussive Symptoms
Interventions
Acceptance and Commitment Therapy, Present Centered Therapy
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
6
States / cities
La Jolla, California • Washington D.C., District of Columbia • Augusta, Maine + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced Oct 28, 2026, 5:07 AM EDT
Not listed Phase 4 Interventional

Efficacy Study of Botox for Depression

NCT01556971
View directory record Official record
Conditions
Major Depression
Interventions
Botox, Saline Solution
Drug
Lead sponsor
Capital Clinical Research Associates, LLC
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Chevy Chase, Maryland • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 19, 2012 · Synced Oct 28, 2026, 5:07 AM EDT