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ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:27 AM EDT

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Showing 1081–1104 of 5,333 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Simulated Dawn Med Students

NCT02088593
View directory record Official record
Conditions
Depression, Anxiety, Fatigue, Sleepiness, Sleep Disruption
Interventions
Simulated Dawn Light Box, Sleep Hygiene instructions
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 28, 2026, 11:27 AM EDT
Terminated Phase 4 Interventional Results available

Sinusitis and Facial Pain Disorders Anti-Depression Trial

NCT00754793
View directory record Official record
Conditions
Chronic Sinusitis, Facial Pain Disorder, Depression
Interventions
escitalopram, placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 17, 2014 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Adults With Fatigue Associated With Major Depressive Disorder

NCT01254305
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Levomilnacipran ER, Paroxetine, Sertraline, Citalopram or Fluoxetine., Placebo
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 65 Years
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
20
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Cerritos, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Phase 3 Interventional Results available

Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression

NCT02600494
View directory record Official record
Conditions
Bipolar Depression
Interventions
ITI-007 (Lumateperone), Placebo
Drug
Lead sponsor
Intra-Cellular Therapies, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
55
States / cities
Little Rock, Arkansas • Rogers, Arkansas • Cerritos, California + 52 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 28, 2026, 11:27 AM EDT
Completed No phase listed Observational

Central Nervous System Disease in HIV-infected Children on HAART

NCT00110331
View directory record Official record
Conditions
HIV Infections, Central Nervous System Diseases
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Emotional and Cognitive Control in Late-Onset Depression

NCT01728194
View directory record Official record
Conditions
Depression
Interventions
Escitalopram, Magnetic Resonance Imaging
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years to 85 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Activating and Connecting Teens (ACT) Study

NCT03438656
View directory record Official record
Conditions
Depression
Interventions
Behavioral Activation
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
12 Years to 18 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Phase 2 Interventional Results available

Ketamine for Depression and Suicide Risk

NCT02094898
View directory record Official record
Conditions
Depression, Suicide
Interventions
Ketamine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 11, 2017 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Phase 3 Interventional Results available

Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Monotherapy)

NCT00868699
View directory record Official record
Conditions
Bipolar Depression
Interventions
lurasidone, Placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
22
States / cities
Escondido, California • Garden Grove, California • Oceanside, California + 18 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2014 · Synced Oct 28, 2026, 11:27 AM EDT
Terminated Phase 2 Interventional Results available

Open Label Extension for GLYX13-C-202, NCT01684163

NCT02192099
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Rapastinel (225 mg/450 mg IV administration)
Drug
Lead sponsor
Naurex, Inc, an affiliate of Allergan plc
Industry
Eligibility
18 Years to 75 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Initiating and Maintaining Physical Activity in Depressed Individuals

NCT02691845
View directory record Official record
Conditions
Depression
Interventions
BA (brief advice), SHE (supervised and home-based exercise), HE (health education), CBEX (cognitive-behavioral sessions focused on increasing and maintaining exercise)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Intervention to Prevent Perinatal Depression and Promote Breastfeeding

NCT04128202
View directory record Official record
Conditions
Depression, Breastfeeding
Interventions
Sunnyside, Sunnyside Plus
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Oct 28, 2026, 11:27 AM EDT
Not yet recruiting Not applicable Interventional

Neuronavigated aiTBS for TRD

NCT07329153
View directory record Official record
Conditions
Treatment Resistant Depression (TRD)
Interventions
aiTBS
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
San Diego, California • New York, New York • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nurse Suicide: Physiologic Sleep Health Promotion Trial

NCT06079853
View directory record Official record
Conditions
Suicide, Nurse's Role, Work Environment Adverse Effects, Sleep, Stress, Mental Health Wellness 1
Interventions
PureSomni Sleep Health Product Kit
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cortlandt Manor, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Oct 28, 2026, 11:27 AM EDT
Not listed Not applicable Interventional

Harnessing Network Science to Personalize Scalable Interventions for Adolescent Depression (TRACK to TREAT Phase 2)

NCT04607902
View directory record Official record
Conditions
Depression
Interventions
Supportive Therapy SSI, Behavioral Activation SSI, Growth Mindset SSI
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
11 Years to 16 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Phase 1 Interventional Results available

Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)

NCT00076245
View directory record Official record
Conditions
Seasonal Affective Disorder, Depression
Interventions
Light Therapy, Cognitive behavioral therapy (CBT)
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pilot RECAP Study in Healthy Volunteers

NCT04842045
View directory record Official record
Conditions
Psychedelic Experiences, Amnesia
Interventions
Psilocybin and Midazolam
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 28, 2026, 11:27 AM EDT
Terminated Phase 4 Interventional Results available

Inflammation-Induced CNS Glutamate Changes in Depression

NCT03004443
View directory record Official record
Conditions
Depression
Interventions
Infliximab, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
21 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 28, 2026, 11:27 AM EDT
Terminated Phase 4 Interventional Results available

Pioglitazone for the Treatment of Bipolar Depression

NCT01717040
View directory record Official record
Conditions
Bipolar Disorder, Insulin Resistance
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 27, 2017 · Synced Oct 28, 2026, 11:27 AM EDT
Completed No phase listed Observational Results available

Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care Clinics

NCT02713217
View directory record Official record
Conditions
Depressive Disorders, Alcohol Use Disorders, Post-traumatic Stress Disorder (PTSD)
Interventions
Usual Care, Blended Telemedicine-Based Integrated Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
North Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 28, 2026, 11:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

NCT02450240
View directory record Official record
Conditions
Depression, Anxiety, Eating Disorders, Drug Use Disorders
Interventions
standardized diagnostic assessment, self-report questionnaires, behavioral tasks, physiological measurements, structural and functional magnetic resonance imaging and EEG, biomarker and microbiome assessments, blood to derive induced pluripotent stem cells, genetic and epigenetic assessments
Behavioral · Other
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
1,271 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

LaPPS: Labor Podcast for Patient Satisfaction

NCT04933708
View directory record Official record
Conditions
Labor Onset and Length Abnormalities, Pregnancy Related
Interventions
Labor Podcast
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Nurtured in Nature

NCT04146025
View directory record Official record
Conditions
Postpartum Depression, Pregnancy Related, Environmental Exposure
Interventions
Nature Coach Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 28, 2026, 11:27 AM EDT
Completed Not applicable Interventional Results available

Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression

NCT01572389
View directory record Official record
Conditions
Diabetes Mellitus, Depression
Interventions
Healthy Outcomes through Patient Empowerment (HOPE), Enhanced Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 28, 2026, 11:27 AM EDT