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ClinicalTrials.gov public records Last synced Oct 29, 2026, 2:06 AM EDT

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Showing 1489–1512 of 5,333 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression Clear all
Not listed Not applicable Interventional

Remote Supervision for Implementing Collaborative Care for Perinatal Depression

NCT02976025
View directory record Official record
Conditions
Perinatal Depression
Interventions
Longitudinal Remote Consultation, Collaborative Care
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Phase 3 Interventional Results available

A 6-Month Extension Study To The B2061032 Study To Evaluate The Safety, Tolerability, And Efficacy Of DVS SR In The Treatment Of Child And Adolescent Outpatients With MDD

NCT01371708
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
DVS SR
Drug
Lead sponsor
Pfizer
Industry
Eligibility
7 Years to 17 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
35
States / cities
Birmingham, Alabama • Tucson, Arizona • Imperial, California + 28 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Study of Mind-Body Skills Groups for Adolescents With Depression in Primary Care

NCT03363750
View directory record Official record
Conditions
Depression, Depressive Disorder
Interventions
mind-body-skills group
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
13 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 29, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Mechanisms of Family-Focused Treatment for Youth Depression

NCT06289010
View directory record Official record
Conditions
Childhood Depression
Interventions
Family-Focused Treatment for Childhood-Depression (FFT-CD)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
7 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Phase 4 Interventional

Self System Therapy and Chronic Low Back Pain Trial

NCT00672880
View directory record Official record
Conditions
Low Back Pain, Depression
Interventions
Self-System Therapy, Education, Standard Care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 29, 2026, 2:06 AM EDT
Not yet recruiting Not applicable Interventional

Empowerment Self Defense Program for Adult Native Women Survivors of Sexual Violence

NCT07712796
View directory record Official record
Conditions
Depression and Quality of Life, Sexual Violence, PTSD, Suicidal Ideation, Problem Drinking
Interventions
Empowerment self-defense training
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pine Ridge, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Phase 4 Interventional Results available

Effect of Bupropion on Seizure Threshold in Depressed Patients

NCT03126682
View directory record Official record
Conditions
MDD
Interventions
Wellbutrin SR 300Mg Extended-Release Tablet
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 29, 2026, 2:06 AM EDT
Recruiting Phase 2 Interventional

A New Intervention to Improve Function in Veterans With Anxiety and Depression

NCT06188923
View directory record Official record
Conditions
Anxiety and Depression
Interventions
Pregnenolone, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindful Moms: Mechanisms of Mindfulness-based Cognitive Therapy During Pregnancy and Postpartum

NCT05137925
View directory record Official record
Conditions
Psychological Distress, Pregnancy Related, Postpartum Blues, Postpartum Depression, Postpartum Anxiety, Postpartum Sadness
Interventions
Mindfulness-Based Cognitive Therapy (MBCT), Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Happy@Home: Delivering iCBT With Homecare Workers to At-Home Seniors

NCT04267289
View directory record Official record
Conditions
Depression
Interventions
Beating the Blues
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing THRIVE 365 for Black Sexual Minority Men (On The Daily)

NCT05376397
View directory record Official record
Conditions
Medication Adherence, Depressive Symptoms, Anxiety Symptoms, Emotion Regulation
Interventions
iTHRIVE 365
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
16 Years and older · Male only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Healthy Expectations - a Program for Pregnant Women Experiencing Depressive Symptoms

NCT02474862
View directory record Official record
Conditions
Depressive Symptoms, Pregnancy
Interventions
Prenatal Walking Program, Postpartum Prep Program
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature

NCT05535062
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
Neuronetics
Other
Eligibility
22 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Sleep and Girls' Emotions Study

NCT04131868
View directory record Official record
Conditions
Depression
Interventions
Typical sleep opportunity, Extended sleep opportunity
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 22 Years · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Oct 29, 2026, 2:06 AM EDT
Recruiting No phase listed Observational

Investigating Dynamic Interactions in Distributed Cognitive Control Networks

NCT05927974
View directory record Official record
Conditions
Cognitive Impairment, Dementia, ADD, Depression
Interventions
Passive testing, Active testing
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women

NCT06353113
View directory record Official record
Conditions
Pregnancy Related, Mental Health Issue, Discrimination, Racial, Stress, Depression
Interventions
Down Dog Prenatal Yoga App
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 46 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Sensory Synchronized Imaging and Neuromodulation

NCT06548113
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
TMS
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

NCT02657317
View directory record Official record
Conditions
Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression, Opioid Use Disorder
Interventions
FORT-A, VA Treatment as Usual
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 72 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

African American Knowledge Optimized for Mindfully Healthy Adolescents

NCT00578318
View directory record Official record
Conditions
Depression
Interventions
Motivational Interviewing Active
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
11 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2013 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Phase 2 Interventional Results available

Clinical Study to Test a New Drug to Treat Major Depression

NCT00976560
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
GW856553, Placebo
Drug · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 60 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
4
States / cities
Hoffman Estates, Illinois • Park Ridge, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2017 · Synced Oct 29, 2026, 2:06 AM EDT
Recruiting Phase 2 Interventional

Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City

NCT07673380
View directory record Official record
Conditions
Opioid Use, Stimulant Use, Depression and Anxiety Symptoms
Interventions
uMAT-R + enhanced community engagement, Original uMAT-R supplementary mHealth recovery intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Phase 4 Interventional

Provigil in Conjunction With SSRIs for the Treatment of Mild or Moderate Depression With Attendant Symptoms of Sleepiness and Fatigue.

NCT00208715
View directory record Official record
Conditions
Major Depression, Mental Health
Interventions
Provigil
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
4
States / cities
Stanford, California • Atlanta, Georgia • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2013 · Synced Oct 29, 2026, 2:06 AM EDT
Completed Phase 2 Interventional Results available

Study of Safety & Tolerability of OPC-34712 as Adjunctive Therapy in Treatment of Adult Patients With Major Depressive Disorder

NCT01447576
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
ADT, OPC-34712
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,036 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
32
States / cities
Arcadia, California • San Diego, California • Sherman Oaks, California + 28 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2015 · Synced Oct 29, 2026, 2:06 AM EDT