Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 11, 2026, 3:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 245 matching trials from the live ClinicalTrials.gov search.
Conditions
Cancer, Depression
Interventions
Behavioral Activation Therapy App, Telehealth Delivered Behavioral Activation
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Major Depressive Disorder, Apathy
Interventions
Targeted Cognitive Training Intervention, General Cognitive Training Intervention
Behavioral
Lead sponsor
AdventHealth
Other
Eligibility
60 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Schizophrenia, Major Depressive Disorder, Bipolar I Disorder
Interventions
Aripiprazole + IEM (Ingestible Event Marker)
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
4
States / cities
Granada Hills, California • Rochester, New York • Durham, North Carolina + 1 more
Conditions
Major Depressive Disorder
Interventions
Levomilnacipran, Quetiapine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Alpharetta, Georgia
Conditions
Depression
Interventions
W-GenZD Mobile Application, Digital Education Application (W-EdZD)
Device
Lead sponsor
Woebot Health
Industry
Eligibility
13 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional

Pilot Sleep Extension and Mood

NCT06675799
Conditions
Internalizing Mental Health Symptoms, Sleep Problems
Interventions
Sleep Extension, Healthy Living Psychoeducation
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Depression, Anxiety
Interventions
Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
Device · Behavioral
Lead sponsor
Woebot Health
Industry
Eligibility
13 Years to 17 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Completed Not applicable Interventional Results available

Mobile Mental Health Apps for Suicide Prevention

NCT04536935
Conditions
Depression, Anxiety, Emotional Regulation
Interventions
Mobile Mental Health App - 1, Mobile Mental Health App - 2, Mobile Mental Health App - 3, Mobile Mental Health App - 4
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
19 Years and older
Enrollment
838 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Obesity, Depression
Interventions
vCare Intervention (6-month active treatment followed by 6-month maintenance), vCare Intervention (active treatment after 6 months)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 74 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • St Louis, Missouri
Conditions
Depression, Treatment Resistant Depression, Major Depressive Disorder, Depressive Disorder
Interventions
Medi-TBS
Combination Product
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
La Jolla, California
Conditions
Depression, Anxiety
Interventions
VIPA Treatment Program, Alexa with Guidebook
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Bipolar Disorder (BD), Bipolar Disorder Depression, Overweight (BMI > 30)
Interventions
Time Restricted Eating
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Perinatal Anxiety, Anxiety Sensitivity, Perinatal Depression
Interventions
Digital mental health intervention
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Leominster, Massachusetts
Completed Phase 4 Interventional Results available

The BIomarker Guided (BIG) Study for Depression

NCT04181736
Conditions
Major Depressive Disorder
Interventions
Guanfacine Tablets
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 69 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Type 2 Diabetes
Interventions
CHW-led T2D Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Suicide, Mental Health Disorder, Anhedonia
Interventions
ViraBrite nudges
Behavioral
Lead sponsor
Ksana Health
Industry
Eligibility
13 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Mental Health Issue, Breast Cancer
Interventions
Digital Micro-Interventions
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Depression, Anxiety
Interventions
Meru Health Program
Behavioral
Lead sponsor
Meru Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Depression, Cancer, Stage III Breast Cancer, Stage II Breast Cancer, Stage I Breast Cancer, Stage III Prostate Cancer, Stage II Prostate Cancer, Stage I Prostate Cancer, Stage III Colorectal Cancer, Stage II Colorectal Cancer, Stage I Colorectal Cancer
Interventions
MINDSET, Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Depression, Depressive Disorder, Depressive Symptoms, Depressive Episode, Adolescent Behavior, Adolescent - Emotional Problem, Hematologic Diseases, Oncology, Weight, Body
Interventions
CBT-based mobile intervention for depression, Mobile control with education about depression
Device
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
13 Years to 22 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Dallas, Texas
Not yet recruiting Not applicable Interventional

Technology dRiven Enhancement to Engage & Connect

NCT06910683
Conditions
Depression
Interventions
TREE-Connect, Clinician-delivered psychotherapy
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
New York, New York
Conditions
Depression
Interventions
Clinical Decision Support System
Device
Lead sponsor
Aifred Health
Industry
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
West Haven, Connecticut • Miami, Florida • Atlanta, Georgia + 2 more
Conditions
Wellness, Quality of Life, Anxiety, Depression
Interventions
Caravan Wellness app
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

The COMParing App Support Strategies Study

NCT07278466
Conditions
Depression, Anxiety
Interventions
Introductory Coaching Session, Introductory Information Session, On-Demand Email Support, Microsupport
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
688 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin