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Showing 1–24 of 1,033 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Depression and Anxiety Symptom Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Resettled Refugee Families for Healing

NCT06176638
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Antisocial Personality Disorder, Anxiety, Aggressive Behavior
Interventions
RRF4H Combination Intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 17 Years
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 26, 2026, 2:28 AM EDT
Recruiting Not applicable Interventional

Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

NCT06812247
View directory record Official record
Conditions
Trauma Injury, Depression, Anxiety, Anger, Pain
Interventions
Therapy dog visits, Dog handler visits
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 26, 2026, 2:28 AM EDT
Recruiting Not applicable Interventional

Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms

NCT05802004
View directory record Official record
Conditions
Acoustic Stimulation
Interventions
Acoustic Stimulation (STIM), No Acoustic Stimulation (SHAM), Daily acoustic stimulation (STIM2), No daily acoustic stimulation (SHAM2)
Device
Lead sponsor
Michelle Stepan
Other
Eligibility
18 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 26, 2026, 2:28 AM EDT
Active, not recruiting No phase listed Observational

Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 (PASC) Using TSPO Positron Emission Tomography (PET) and MRI

NCT05615415
View directory record Official record
Conditions
Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 Infection
Interventions
PET Tracer, MRI Tracer, 3T PET/MRI
Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Not applicable Interventional

Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer

NCT01764789
View directory record Official record
Conditions
Anxiety Disorder, Depression, Fatigue, Leydig Cell Tumor, Ovarian Sarcoma, Ovarian Stromal Cancer, Pain, Peritoneal Carcinomatosis, Pseudomyxoma Peritonei, Recurrent Breast Cancer, Recurrent Cervical Cancer, Recurrent Endometrial Carcinoma, Recurrent Fallopian Tube Cancer, Recurrent Gestational Trophoblastic Tumor, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Cavity Cancer, Recurrent Uterine Sarcoma, Recurrent Vaginal Cancer, Recurrent Vulvar Cancer
Interventions
questionnaire administration, quality-of-life assessment, psychosocial assessment and care, behavioral intervention, cognitive intervention, educational intervention
Other · Procedure · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 85 Years · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Not applicable Interventional

Impact of Massage Therapy and Music Therapy on the Quality of Life of Hospice Patients

NCT03217682
View directory record Official record
Conditions
Pain, Anxiety, Depression, Quality of Life
Interventions
Music Therapy, Massage Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Not applicable Interventional

Telehealth Cognitive Behavioral Stress Management for Adults With Cystic Fibrosis

NCT03560726
View directory record Official record
Conditions
Anxiety, Depression, Stress, Coping Skills, Cystic Fibrosis
Interventions
Cognitive Behavioral Stress Management
Behavioral
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 8, 2020 · Synced Sep 26, 2026, 2:28 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Storytelling and Mindfulness for Graduate Student Wellbeing

NCT05826860
View directory record Official record
Conditions
Depression, Anxiety, Burnout, Student
Interventions
Mindfulness Practice, Storytelling Workshop
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Not applicable Interventional

Hypnotherapy in Treating Chronic Pain in Cancer Survivors

NCT02637297
View directory record Official record
Conditions
Anxiety, Cancer Survivor, Chronic Pain, Depression, Sleep Disorder
Interventions
Hypnotherapy, Questionnaire Administration
Procedure · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced Sep 26, 2026, 2:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

NCT00579267
View directory record Official record
Conditions
Major Depression, Mania, Anxiety Disorders, Psychotic Disorder, Alcohol Dependence, Drug Dependence, Eating Disorders, Suicidality, Dysthymia, ADHD, Tourettes Disorder, Conduct Disorder, Oppositional Defiant Disorder, Pervasive Developmental Disorder
Interventions
MINI-KID
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 17 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 15, 2009 · Synced Sep 26, 2026, 2:28 AM EDT
Not listed Phase 4 Interventional

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

NCT04245436
View directory record Official record
Conditions
Anxiety, Depressive Symptoms
Interventions
Duloxetine, Escitalopram
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Sep 26, 2026, 2:28 AM EDT
Withdrawn No phase listed Observational

A Prospective Study of Body Image, Social Avoidance and Distress and Psychological Functioning in Burn Patients

NCT01136070
View directory record Official record
Conditions
Depression, Anxiety, Body Image
Interventions
Not listed
Lead sponsor
Saint Elizabeth Regional Medical Center
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 12, 2016 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of CES on Emotional and Cellular Wellbeing

NCT03369418
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Alpha-Stim Active, Alpha-Stim Inactive
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Sep 26, 2026, 2:28 AM EDT
Recruiting Not applicable Interventional

Sleep Mechanisms Of Regulating Emotions

NCT06373718
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 26, 2026, 2:28 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ginger.io Behavioral Health Study

NCT02491307
View directory record Official record
Conditions
Anxiety, Depression, Bipolar I Disorder, Bipolar II Disorder
Interventions
Ginger.io Smartphone Application
Other
Lead sponsor
Community Health Center, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
4
States / cities
Meriden, Connecticut • Middletown, Connecticut • New Britain, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Sep 26, 2026, 2:28 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Recurrence Markers, Cognitive Burden and Neurobiological Homeostasis in Late-Life Depression

NCT05331599
View directory record Official record
Conditions
Depression in Old Age, Recurrence, Cognitive Dysfunction
Interventions
Not listed
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
60 Years and older
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Sep 26, 2026, 2:28 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Mobile Phone App for Depression and Anxiety in Young Men Who Are Attracted to Men

NCT02072252
View directory record Official record
Conditions
Depressive Symptoms, Anxiety Generalized
Interventions
Mobile Phone Application
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
17 Years to 20 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 16, 2017 · Synced Sep 26, 2026, 2:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ascertaining Diagnosis Classification With Elicited Speech

NCT05601063
View directory record Official record
Conditions
Schizophrenia Spectrum and Other Psychotic Disorders, Bipolar and Related Disorders, Depressive Disorder, Anxiety Disorders, Personality Disorders, Attention Deficit Hyperactivity Disorder
Interventions
Winterlight Speech Assessment
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
14 Years to 50 Years
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 26, 2026, 2:28 AM EDT
Active, not recruiting Not applicable Interventional

Testing FIRST in Youth Outpatient Psychotherapy

NCT04725721
View directory record Official record
Conditions
Anxiety, Depression, Trauma, Behavior Problem
Interventions
FIRST, Usual Care
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
7 Years to 15 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Cambridge, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Student Outcomes of Integrative Mental Health Services

NCT02877875
View directory record Official record
Conditions
Anxiety, Depression, Trauma, Behavior Problems
Interventions
Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System, Treatment as usual
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
7 Years to 14 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 26, 2026, 2:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining Prison Inmates' Attitudes and Internal Emotional States

NCT04374357
View directory record Official record
Conditions
Forgiveness
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Male only
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Portage, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Phase 2 Interventional

Coping With Adolescent Peer Victimization and Reducing Anxious/Depressed Symptoms

NCT02011438
View directory record Official record
Conditions
Depression, Social Anxiety
Interventions
UTalk
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 18 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Dec 16, 2015 · Synced Sep 26, 2026, 2:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindful Moms: Mechanisms of Mindfulness-based Cognitive Therapy During Pregnancy and Postpartum

NCT05137925
View directory record Official record
Conditions
Psychological Distress, Pregnancy Related, Postpartum Blues, Postpartum Depression, Postpartum Anxiety, Postpartum Sadness
Interventions
Mindfulness-Based Cognitive Therapy (MBCT), Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 26, 2026, 2:28 AM EDT
Active, not recruiting Not applicable Interventional

Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care

NCT06019377
View directory record Official record
Conditions
Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior, Utilization, Health Care, Depression, Anxiety, Stress Disorders, Post-Traumatic, Emotion Regulation, Child Welfare
Interventions
Stronger Youth Networks and Coping (SYNC)
Behavioral
Lead sponsor
Portland State University
Other
Eligibility
16 Years to 20 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 26, 2026, 2:28 AM EDT