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ClinicalTrials.gov public records Last synced Oct 7, 2026, 9:21 PM EDT

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Showing 73–96 of 1,035 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression and Anxiety Symptom Clear all
Active, not recruiting Not applicable Interventional

Whole Health in VA Mental Health: Omnis Salutis

NCT05400252
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depressive Disorder, Anxiety Disorders, Substance-Related Disorders
Interventions
Omnis Salutis, Health and Wellness
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Aurora, Colorado • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Enrolling by invitation Not applicable Interventional

Voice Analysis Technology to Detect and Manage Depression and Anxiety in Cardiac Rehabilitation

NCT05371470
View directory record Official record
Conditions
Myocardial Infarction
Interventions
Ellipsis Health Voice Application
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations

NCT01093053
View directory record Official record
Conditions
Stress Disorders, Post Traumatic, Brain Injuries, Depressive Disorder, Anxiety Disorders, Anger
Interventions
Mind-Body Skills Groups, Standard Treatment
Behavioral · Other
Lead sponsor
The Center for Mind-Body Medicine
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 29, 2014 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional

Web-based Management of Pediatric Functional Abdominal Pain

NCT02327377
View directory record Official record
Conditions
Gastrointestinal Disorders, Functional
Interventions
Online Cognitive Behavior Therapy, Online Education
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
11 Years to 17 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 28, 2019 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional Results available

Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration

NCT04785677
View directory record Official record
Conditions
Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Depressive Symptoms, Anxiety, Substance Use, Aggression, Coping Skills, Impulsive Behavior, Housing Problems, Recidivism, Stress, Occupational Stress, Psychological Distress
Interventions
Resiliency in Stressful Experiences (RISE) Program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Recruiting Phase 2 Interventional

HBOT Effects on First Responders' Cognition and Well-Being

NCT07852728
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Personalized Mind-Body Intervention (MBI) for Improving Sleep Among Women Working in Healthcare

NCT05789212
View directory record Official record
Conditions
Sleep Insufficiency
Interventions
Personalized Trial ABCCBA, Personalized Trial CBAABC
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of Two On-Line Interventions for Child Brain Injury

NCT00178022
View directory record Official record
Conditions
Traumatic Brain Injury, Depression, Anxiety Disorders
Interventions
Case management and problem solving therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2008 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional

Low Intensity Focused Ultrasound: a New Paradigm for Depression and Anxiety

NCT05147142
View directory record Official record
Conditions
Depression
Interventions
Low Intensity Focused Ultrasound
Device
Lead sponsor
Ocean State Research Institute, Inc.
Other
Eligibility
22 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Completed No phase listed Observational

My Experiences: Leveraging Digital Technologies to Better Understand Mental Health

NCT05753605
View directory record Official record
Conditions
Mental Health Symptoms, Wearables
Interventions
Not listed
Lead sponsor
4YouandMe
Other
Eligibility
18 Years and older
Enrollment
302 participants
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 7, 2026, 9:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program

NCT05789446
View directory record Official record
Conditions
Chronic Stress, Anxiety, Depression
Interventions
Building a Strong Identity and Coping Skills
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
11 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
5
States / cities
Harrisburg, Pennsylvania • Hershey, Pennsylvania • Spring Mills, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Open-Label Psilocybin Study in Transdiagnostic Population

NCT06442423
View directory record Official record
Conditions
Transdiagnostic, Depression - Major Depressive Disorder, Anxiety, PTSD Symptoms, PTSD, Substance Use, Substance Use Disorder (SUD), OCD
Interventions
Psilocybin
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maine Implementation Study - Phase III

NCT02229305
View directory record Official record
Conditions
Anxiety, Trauma, Depression, Problem Behavior
Interventions
Usual Care Treatment, Modular Approach to Therapy for Children
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
6 Years to 15 Years
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2014 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional

The Clinic Treatment Project

NCT01178554
View directory record Official record
Conditions
Anxiety, Depression, Problem Behavior
Interventions
psychotherapy, evidence-based treatment, modular evidence-based treatment
Behavioral
Lead sponsor
Judge Baker Children's Center
Other
Eligibility
7 Years to 13 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
2
States / cities
Honolulu, Hawaii • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2011 · Synced Oct 7, 2026, 9:21 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Occupational Therapy for Mental Health and Engagement in Neurorehabilitation

NCT07375485
View directory record Official record
Conditions
Acquired Brain Injury, Mental Health, Depressive Symptoms, Anxiety Symptoms, Loneliness
Interventions
Multifaceted implementation program
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Denver, Colorado • Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Active, not recruiting Not applicable Interventional

Testing FIRST in Youth Outpatient Psychotherapy

NCT04725721
View directory record Official record
Conditions
Anxiety, Depression, Trauma, Behavior Problem
Interventions
FIRST, Usual Care
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
7 Years to 15 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Cambridge, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 7, 2026, 9:21 PM EDT
Completed No phase listed Observational

Negative-Positive Valence Domains in Anxiety and Depression

NCT03310398
View directory record Official record
Conditions
Anxiety, Depression
Interventions
NeuroImaging, Psychophysiological
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 55 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Trauma-Informed Approach for Positive Youth Development for Montana Students

NCT04664855
View directory record Official record
Conditions
Depression, Anxiety, Suicidal Ideation, Stress, Trauma
Interventions
Trauma-Informed Yoga
Other
Lead sponsor
Montana State University
Other
Eligibility
14 Years to 19 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications

NCT04419168
View directory record Official record
Conditions
Chronic Pain, Depression, Anxiety, Opioid Use
Interventions
cCBT, m-Education
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
7
States / cities
Chicago, Illinois • Baltimore, Maryland • Durham, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 7, 2026, 9:21 PM EDT
Withdrawn Not applicable Interventional

The Impact of Mindfulness Meditation in Veterans With Epilepsy

NCT03589755
View directory record Official record
Conditions
Epilepsy
Interventions
Mindfulness meditation
Behavioral
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 7, 2026, 9:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

To Increase Psychological Well-being by the Implementation of Forgiveness Education

NCT04403126
View directory record Official record
Conditions
Anger, Depressive Symptoms, Anxiety
Interventions
forgiveness education intervention
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
10 Years to 65 Years
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Oct 7, 2026, 9:21 PM EDT
Not listed Not applicable Interventional

Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders

NCT06502717
View directory record Official record
Conditions
Mental Health Issue, Depression, Anxiety
Interventions
VIOME Precision Nutrition Program
Combination Product
Lead sponsor
Viome
Industry
Eligibility
25 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 7, 2026, 9:21 PM EDT