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ClinicalTrials.gov public records Last synced Oct 14, 2026, 2:09 PM EDT

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Showing 433–456 of 1,044 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression and Anxiety Symptoms Clear all
Completed Not applicable Interventional Results available

Primary-Care Based Mindfulness Intervention

NCT03922581
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Major Depressive Disorder
Interventions
Mindfulness-Based Cognitive Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 14, 2026, 2:09 PM EDT
Not yet recruiting Not applicable Interventional

Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings

NCT07755137
View directory record Official record
Conditions
Autism Spectrum Disorder, Depressive Disorder, Anxiety Disorders
Interventions
CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU)
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
11 Years to 17 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Sexual Dysfunction, Depression and Anxiety in Underserved, Minority Gynecologic Cancers Patients

NCT01031602
View directory record Official record
Conditions
Gynecologic Cancer
Interventions
Surveys
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Oct 14, 2026, 2:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Physician Mental Health Study for Medical Trainees

NCT02950363
View directory record Official record
Conditions
Mental Illness, Burnout Syndrome
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2017 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Amplification of Positivity to Enhance Social Connections in Anxiety and Depression

NCT04945239
View directory record Official record
Conditions
Depression, Anxiety Disorders and Symptoms
Interventions
Amplification of Positivity Training (6 Sessions), Stress Management Training (6 Sessions)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 55 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological Outcomes

NCT04510272
View directory record Official record
Conditions
Anxiety, Depression, PTSD
Interventions
Aloud Real-time Reading of ICU Diaries
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stay Well at Home: a Text-messaging Study Social Distancing

NCT04473599
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, COVID-19
Interventions
Uniform random message delivery, Reinforcement learning message delivery, Mood ratings only
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Oct 14, 2026, 2:09 PM EDT
Recruiting Phase 2 Interventional

Cannabis for Palliative Care in Cancer

NCT06266611
View directory record Official record
Conditions
Sleep, Anxiety, Depression, Pain
Interventions
fsCBD Cannabidiol, Placebo, bsCBD Cannabidiol
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
25 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2025 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Electronic Media and Its Application in Psychotherapy

NCT03712267
View directory record Official record
Conditions
Anxiety Disorders, Depression, Electronic Media
Interventions
Electronic Media Enhanced, Treatment as Usual
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
14 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Single-Session Intervention Targeting Emotional Awareness, Clarity, and Acceptance to Reduce Depression/Anxiety

NCT05109507
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Visitor Mindset, Relaxing with Nature
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 29, 2021 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Mindfulness Intervention in Reducing Anxiety in Patients Who Have Been Treated for Gynecologic Cancer

NCT02518308
View directory record Official record
Conditions
Anxiety, Cancer Survivor, Cognitive Impairment, Depression, Distress, Fatigue, Malignant Female Reproductive System Neoplasm, Pain, Sexual Dysfunction
Interventions
Mindfulness-Based Stress Reduction
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention

NCT06365645
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Stress
Interventions
M.Bapp, App-based parenting education
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Enhancing Engagement by Integrating Goals and Concerns That Matter to Patients

NCT06898593
View directory record Official record
Conditions
Anxiety Disorders, Depression Disorders
Interventions
Collaborative care model with clinical decision support system, Collaborative care model
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
2,448 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Concord, New Hampshire • Lebanon, New Hampshire • Manchester, New Hampshire + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Digital Single Session Intervention for Youth Mental Health

NCT05449002
View directory record Official record
Conditions
Anxiety, Depression, Conduct Disorder, Stress
Interventions
Practicing the Opposite (PTO), Usual Clinical Care
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
9 Years to 17 Years
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
5
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Concord, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy of a Multi-level School Intervention for LGBTQ Youth

NCT05541406
View directory record Official record
Conditions
Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior, Sexual Minority Stress, Suicidality, Substance Use, Bullying, Harassment
Interventions
Proud & Empowered, Control Group
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 20 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
23
States / cities
El Monte, California • Glendale, California • Inglewood, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer

NCT06636721
View directory record Official record
Conditions
Lung Cancer
Interventions
LuCA Behavioral Intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Treatment for Veterans With Military Sexual Trauma

NCT00371644
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depressive Symptoms, Anxiety Symptoms, Quality of Life
Interventions
Cognitive Processing Therapy, Present-Centered Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2015 · Synced Oct 14, 2026, 2:09 PM EDT
Completed No phase listed Observational

Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics

NCT03947099
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Anxiety Disorders
Interventions
Ketamine Hydrochloride
Drug
Lead sponsor
Klarisana Physician Services PLLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 14, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Building Connections

NCT07091032
View directory record Official record
Conditions
Cancer Colorectal, Cancer Cervix, Depression, Anxiety, Obesity
Interventions
Treatment as Usual, Building Connections Intervention
Other · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
3,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 14, 2026, 2:09 PM EDT
Completed No phase listed Observational

Pharmacogenomics of Antidepressant Response in Children and Adolescents

NCT00516932
View directory record Official record
Conditions
Anxiety Disorders, Depression, Eating Disorders, Obsessive-Compulsive Disorder, Suicide Prevention
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
7 Years to 17 Years
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2015 · Synced Oct 14, 2026, 2:09 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Maternal Mental Health & SUD Screening and Treatment

NCT05764213
View directory record Official record
Conditions
Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
Interventions
Listening to Women & Pregnant and Postpartum People
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10,470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Chronic Pelvic Pain and Education Skills Training for Women Veterans

NCT05368155
View directory record Official record
Conditions
Pelvic Pain, Depression, Anxiety
Interventions
Brief ACT for Pelvic Pain
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2023 · Synced Oct 14, 2026, 2:09 PM EDT
Recruiting Phase 1 Interventional

Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency

NCT04789148
View directory record Official record
Conditions
Vasopressin Deficiency
Interventions
Intranasal Oxytocin (IN-OXT), Placebo
Drug
Lead sponsor
Elizabeth Austen Lawson
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 14, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention

NCT06143852
View directory record Official record
Conditions
Social Media Addiction, Depression, Anxiety, Well-Being, Psychological
Interventions
Mindfulness, Social Media Reduction + Exercise
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 14, 2026, 2:09 PM EDT