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ClinicalTrials.gov public records Last synced Oct 14, 2026, 5:35 PM EDT

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Showing 457–480 of 1,044 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression and Anxiety Symptoms Clear all
Completed Not applicable Interventional

The Impact of Three Distinct Exercise Types on Fatigue, Anxiety, and Depression in Parkinson's Disease

NCT03833349
View directory record Official record
Conditions
Parkinson Disease
Interventions
Spinning Class, Yoga Class, Dance Class
Behavioral
Lead sponsor
Premier Health
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Lebanon, New Hampshire • Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effect of EFT on Psychological States in a Veterans Population

NCT00743041
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Emotional Freedom Techniques (EFT)
Behavioral
Lead sponsor
Soul Medicine Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Santa Rosa, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 14, 2026, 5:35 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Hatha Yoga on Mental Health

NCT05777044
View directory record Official record
Conditions
Depression, Anxiety, Mental Health Issue
Interventions
Yoga
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Results available

BRITEPath- Phase 2

NCT04672798
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
BRITEPath, Treatment As Usual (TAU)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 26 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
Detroit, Michigan • Hyde Park, New York • Moon Township, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Results available

Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders

NCT01947647
View directory record Official record
Conditions
Major Depressive Disorder, Persistent Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder, Social Phobia, Specific Phobia, Generalized Anxiety Disorder, Obsessive Compulsive Disorder
Interventions
Transdiagnostic Behavior Therapy, Behavioral Activation Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Phase 2 Interventional

Brief CBT for Anxiety and Advanced Cancer

NCT00706290
View directory record Official record
Conditions
Anxiety, Depression, Unspecified Adult Solid Tumor, Protocol Specific, Cancer, Cognitive Behavioral Therapy
Interventions
Brief Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 6, 2014 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SSIs for Mental Health and Loneliness

NCT05687162
View directory record Official record
Conditions
Loneliness, Mental Health Issue, Distress, Emotional, Depression, Anxiety, Stress
Interventions
Overcoming Loneliness three-week intervention, Overcoming Loneliness single-session intervention, Single-session "Sharing Feelings" program, The Blu Surfer program: a popular online content-based intervention for psychological distress, The Action Brings Change (ABC) Program (TEAM Lab version), Online help-seeking as usual, The Lonely Blu Surfer program: a popular online content-based intervention for loneliness, Overcoming loneliness SSI 8-minute version
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
16 Years and older
Enrollment
4,370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Oct 14, 2026, 5:35 PM EDT
Completed No phase listed Observational

Psychosocial Correlates and Coping Strategies Associated With Long-Term Survival of HIV-Infected Children

NCT00001435
View directory record Official record
Conditions
Acquired Immunodeficiency Syndrome, Depressive Disorder, HIV Infections
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile Technology and Data Analytics to Identify Real-time Predictors of Caregiver Well-Being

NCT04556591
View directory record Official record
Conditions
Caregivers
Interventions
Just-in-time adaptive intervention (JITAI), Control
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Oct 14, 2026, 5:35 PM EDT
Recruiting No phase listed Observational

MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

NCT07540585
View directory record Official record
Conditions
Anxiety Disorders, Stress Disorders, Post-Traumatic, Pregnancy, High Risk, Depressive Disorder, Major, Pregnancy Complications, ADHD - Attention Deficit Disorder With Hyperactivity
Interventions
Collaborative Mental Health Care Program (CMHCP)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 14, 2026, 5:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen

NCT04684615
View directory record Official record
Conditions
Depression, Anxiety, Bipolar Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Drumming Groups for Parents of Autistic Children

NCT07375043
View directory record Official record
Conditions
Anxiety Acute, Stress, Depression and Quality of Life, Stress in Parents of Autistic Children
Interventions
Group Drumming
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Results available

A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers

NCT04816708
View directory record Official record
Conditions
Emotional Distress, Burnout, Professional, Stress, Job, Anxiety, Depressive Symptoms
Interventions
LIFT Mindfulness
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 14, 2026, 5:35 PM EDT
Not listed Not applicable Interventional

NeuroGlove Anxiety and Depression Study

NCT06065787
View directory record Official record
Conditions
Anxiety, Depression, Anxiety Depression, Depression, Anxiety
Interventions
NeuroGlove
Device
Lead sponsor
NeuroGlove LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Results available

Development of a Patient Centered Mental Health Intervention for Recent Veterans

NCT02943408
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Anxiety, Substance-Related Disorders
Interventions
person-centered mental health intervention, health and wellness
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
3
States / cities
Baltimore, Maryland • Perry Point, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls

NCT04498442
View directory record Official record
Conditions
Covid19, Stress, Anxiety Depression
Interventions
Simha Kriya, Reading a Book
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
8,519 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 14, 2026, 5:35 PM EDT
Recruiting Phase 3 Interventional

Nebulized Ketamine for the Treatment of Major Depressive Disorder

NCT06752759
View directory record Official record
Conditions
Severe Depression, Moderate Depression, Ketamine, Midazolam, Peripheral Nervous System Agents, Central Nervous System Agents, Neurotransmitter Agents, Physiologic Effects of Drugs, Sensory System Agents, Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal, Depressive Symptom, Hypnotics and Sedatives, Anti-anxiety Agents, Tranquilizing Agents, Psychotropic Drugs, Anesthetics Agent
Interventions
nebulized ketamine, nebulized midazolam
Drug
Lead sponsor
Theresa Jacob, PhD, MPH
Other
Eligibility
18 Years to 88 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Phase 4 Interventional Results available

Escitalopram (Lexapro) for the Treatment of Postpartum Depression

NCT00833469
View directory record Official record
Conditions
Postpartum Depression
Interventions
Escitalopram
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 14, 2026, 5:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program

NCT06652503
View directory record Official record
Conditions
Anxiety, Depression, Stress, Wellbeing, Quality of Life
Interventions
online mental health coaching
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 14, 2026, 5:35 PM EDT
Not yet recruiting Not applicable Interventional

Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0)

NCT07645274
View directory record Official record
Conditions
Diagnoses of Depression, Anxiety, PTSD
Interventions
PARTNER-MH, Educational Brochure
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
2
States / cities
Indianapolis, Indiana • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 14, 2026, 5:35 PM EDT
Active, not recruiting No phase listed Observational

The BEAR Therapeutic Program for Women

NCT04418778
View directory record Official record
Conditions
Trauma, Psychological, Depression, Anxiety, PTSD
Interventions
BEAR
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Medical Marijuana on Neurocognition and Escalation of Use

NCT03224468
View directory record Official record
Conditions
Pain, Insomnia, Depression, Anxiety
Interventions
Medical Marijuana
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 15, 2023 · Synced Oct 14, 2026, 5:35 PM EDT
Recruiting Not applicable Interventional

Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

NCT06049420
View directory record Official record
Conditions
Obesity, Hyperlipidemias, Polycystic Ovary Syndrome, Hypertension, Coronary Heart Disease, Heart Failure, Depression, Anxiety, Type II Diabetes, Metabolic Syndrome
Interventions
Lifestyle counseling and coaching
Behavioral
Lead sponsor
West Virginia School of Osteopathic Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lewisburg, West Virginia
Source: ClinicalTrials.gov public record
Updated Jul 25, 2025 · Synced Oct 14, 2026, 5:35 PM EDT
Completed Not applicable Interventional Results available

Mobile Apps to Reduce Distress in Breast Cancer Survivors Using an Adaptive Design

NCT04583891
View directory record Official record
Conditions
Depression, Anxiety, Engagement, Patient
Interventions
IntelliCare, Psychoeducation, Coaching
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 14, 2026, 5:35 PM EDT