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ClinicalTrials.gov public records Last synced Oct 15, 2026, 11:38 AM EDT

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Showing 745–768 of 1,044 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression and Anxiety Symptoms Clear all
Completed Not applicable Interventional

Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

NCT03904186
View directory record Official record
Conditions
Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking, Anxiety, Depression, Nicotine Dependence
Interventions
QUIT, Time-Matched Control (TM)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional

An Attachment Based Approach for Anxiety and Depression

NCT04719780
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Emotionally Focused Therapy for Individuals, Self-Help CBT Training
Behavioral
Lead sponsor
Saint Paul University
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Self-Defense Training in Women With Trauma

NCT01380379
View directory record Official record
Conditions
Depression, Anxiety, Stress Disorders, Post-Traumatic
Interventions
Life skills and self-defense training
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

The Efficacy of Cranial Electrostimulating Therapy for Depression and Anxiety Among Homeless Adults

NCT02732561
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Alpha Stim device, Sham device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Positive Valence System Enhancement Treatment for Anxiety and Depression: Clinical Efficacy and Neural Changes

NCT02330627
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression
Interventions
Positive Valence System Treatment
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention

NCT06143852
View directory record Official record
Conditions
Social Media Addiction, Depression, Anxiety, Well-Being, Psychological
Interventions
Mindfulness, Social Media Reduction + Exercise
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

NCT00819208
View directory record Official record
Conditions
Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Sleep Disorders, Excercise
Interventions
exercise intervention, counseling intervention, Educational Intervention, laboratory biomarker analysis, questionnaire administration, study of socioeconomic and demographic variables, fatigue assessment and management, quality-of-life assessment, Fitness testing
Behavioral · Other · Procedure
Lead sponsor
Canadian Cancer Trials Group
Network
Eligibility
18 Years and older
Enrollment
889 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2026
U.S. locations
3
States / cities
Detroit, Michigan • Lebanon, New Hampshire • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

NCT05567640
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depressive Symptoms
Interventions
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP), Space for depression, Space for resilience
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
1,800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep More, Stress Less: 90-Day Trial of Neuralli Mood

NCT07717385
View directory record Official record
Conditions
Psychological Stress, Sleep Disturbance, Anxiety Symptoms, Depressive Symptoms, Occupational Burnout
Interventions
Neuralli Mood
Dietary Supplement
Lead sponsor
Efforia, Inc
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Educational Counseling in Improving Communication and Quality of Life in Spouses and Breast Cancer Patients

NCT01723943
View directory record Official record
Conditions
Anxiety Disorder, Depression, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ, Psychosocial Effects of Cancer and Its Treatment, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer
Interventions
educational intervention, counseling intervention, psychosocial support for caregiver
Other
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 8, 2018 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality Biofeedback for Postpartum Anxiety and Depression

NCT04925765
View directory record Official record
Conditions
Anxiety and Depression, Postpartum Depression, Pregnancy Related
Interventions
Virtual Reality Biofeedback Session
Other
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Biofeedback for Psoriasis

NCT05506644
View directory record Official record
Conditions
Psoriasis, Psoriasis Vulgaris, Psychophysiological Disorder, Anxiety, Depression, Psychological Stress, Physiological Stress, Quality of Life, Skin Disorder, Skin Diseases
Interventions
HRV-Biofeedback/Mind-Body Therapy
Other
Lead sponsor
Bastyr University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Primary-Care Based Mindfulness Intervention

NCT03922581
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Major Depressive Disorder
Interventions
Mindfulness-Based Cognitive Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 15, 2026, 11:38 AM EDT
Suspended Not applicable Interventional

Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)

NCT07102212
View directory record Official record
Conditions
Lung Cancer, Breast Cancer, Prostate Cancer, Multiple Myeloma, Melanoma
Interventions
mHealth Intervention
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Recruiting Phase 2 Interventional

Adolescent Chatbot

NCT07094503
View directory record Official record
Conditions
Body Image Disturbance, Disordered Eating Behaviors, Eating Disorder Prevention
Interventions
Wysa Digital Chatbot Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
13 Years to 19 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Active, not recruiting Not applicable Interventional

Adapting a Health at Every Size Intervention to Obstetric Care

NCT06919783
View directory record Official record
Conditions
Weight Stigma
Interventions
Health at Every Size in Obstetrics
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Recruiting No phase listed Observational

An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression

NCT05466851
View directory record Official record
Conditions
Depression, Anxiety Disorders, Stress Related Disorder
Interventions
Not listed
Lead sponsor
Singula Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 15, 2026, 11:38 AM EDT
Not listed Not applicable Interventional

Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems

NCT02868983
View directory record Official record
Conditions
Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes, Heart Failure, Hypertension, Anxiety, Chronic Pain, Depression, Fibromyalgia, Insomnia, Irritable Bowel Syndrome, Problem Drinking, Substance Use Disorder
Interventions
Integration
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
4,025 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional

Cognitive Training for Mood and Anxiety Disorders

NCT02256566
View directory record Official record
Conditions
Major Depressive Disorder, Depression, Bipolar Disorder, Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Social Phobia
Interventions
emotional memory training exercise, memory training exercise
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 15, 2026, 11:38 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

BEhavioral Health Stratified Treatment (BEST) Study for Youth With Intellectual and/or Developmental Disabilities (IDD)

NCT05520983
View directory record Official record
Conditions
Depression, Anxiety, Transition
Interventions
Adapted Teens Achieving Mastery over Stress (TEAMS) Treatment, Adapted Teens Achieving Mastery over Stress (TEAMS) Prevention, Adapted Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT), Strengthening Families, Virtual psycho-educational discussion groups for caregivers and participants, Maternal Child Health Bureau (MCHB) Care Coordination
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
13 Years to 20 Years
Enrollment
780 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Comprehensive vs. Assisted Management of Mood and Pain Symptoms

NCT01757301
View directory record Official record
Conditions
Pain, Depression, Anxiety, Musculoskeletal, Fibromyalgia
Interventions
Assisted Symptom Management (ASM), Comprehensive Symptom Management (CSM)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional

UCSF TARA Study: Training for Awareness, Resilience and Action

NCT02480257
View directory record Official record
Conditions
Depression, Anxiety
Interventions
TARA
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
14 Years to 18 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Single-Session Intervention for Adolescents and Young Adults With Internalizing Problems

NCT05826392
View directory record Official record
Conditions
Anxiety, Depressive Symptoms
Interventions
Adolescent/Young Adult Self-Administered Web-Based Single-Session Intervention
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
13 Years to 24 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 15, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Lodge First Face Training Evaluation Study

NCT06290180
View directory record Official record
Conditions
Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
Interventions
First Face for Mental Heatlh
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
Not listed
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Spokane Valley, Washington
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 15, 2026, 11:38 AM EDT