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ClinicalTrials.gov public records Last synced Nov 14, 2026, 1:53 AM EST

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Showing 1–24 of 165 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depression and Suicide Clear all

Conditions: Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior, Sexual Minority Stress, Suicidality, Substance Use, Bullying, Harassment
Interventions: Proud & Empowered, Control Group; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 12 Years to 20 Years
Enrollment: 228 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 23
States / cities: El Monte, California • Glendale, California • Inglewood, California + 7 more

Conditions: Suicide, Suicidal Ideation, Suicidal Impulses, Suicidal Intention, Suicidal and Self-Injurious Behavior, Suicidal Depression
Interventions: Neuronetics NeuroStar XPLOR magnetic stimulator - Active, Neuronetics NeuroStar XPLOR magnetic stimulator - Sham; Device
Lead sponsor: Eisenhower Army Medical Center; Federal
Eligibility: 18 Years to 60 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Bipolar Depression, Suicidal Ideation
Interventions: Ketamine Hydrochloride, Placebo; Drug
Lead sponsor: NeuroRx, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 2
States / cities: Hollywood, Florida • Fort Worth, Texas

Conditions: Depressive Disorder, Major Depressive Disorder, Bipolar Disorder, Post Traumatic Stress Disorder, Suicidal Ideation
Interventions: Perampanel 6 MG, Ketamine, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2033
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Suicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, Suicide
Interventions: Stepped Care for Suicide Prevention, Zero Suicide Quality Improvement; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 12 Years to 24 Years
Enrollment: 301 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Los Angeles, California • Portland, Oregon

Conditions: Self-Harm, Depression, Suicide
Interventions: N-acetyl cysteine, Placebo oral tablet; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 16 Years to 24 Years · Female only
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Depression and Suicide, Mood Disorders, Other Perinatal Conditions
Interventions: Not listed
Lead sponsor: Michigan State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 209 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 3
States / cities: Grand Rapids, Michigan

Conditions: Depression, Suicidal Ideation, Major Depressive Disorder, Depressive Disorder
Interventions: "Engage & Connect" Psychotherapy, Symptom Review and Psychoeducation (SRP); Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 50 Years to 80 Years
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression, Depression Severe, Depression Acute, Depression and Suicide, Suicidal Ideation
Interventions: Ketamine, Sodium Chloride 0.9%; Drug
Lead sponsor: MercyOne Des Moines Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Des Moines, Iowa

Conditions: Depression, Suicidal Ideation
Interventions: Making Connections Intervention, IPT-A; Behavioral
Lead sponsor: New York University; Other
Eligibility: 12 Years to 20 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: New York, New York

Conditions: Major Depressive Disorder
Interventions: Group IPT for Depression + TAU; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 5
States / cities: Bridgewater, Massachusetts • Framingham, Massachusetts • Norfolk, Massachusetts + 1 more

Conditions: Depression
Interventions: Risperidone and placebo comparator; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Adolescent Suicide, Adolescent Depression
Interventions: Ketamine Infusion, Midazolam Infusion; Drug
Lead sponsor: Yale University; Other
Eligibility: 13 Years to 17 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Suicide, Nurse's Role, Work Environment Adverse Effects, Sleep, Stress, Mental Health Wellness 1
Interventions: PureSomni Sleep Health Product Kit; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 21 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Cortlandt Manor, New York

Conditions: Depression, Suicidal Ideation
Interventions: "screening as usual", Screening Wizard 2.0, Screening Wizard 2.0 + SOVA; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 26 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder, Suicidal Ideation
Interventions: Collaborative care Plus; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 12
States / cities: Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 3 more

Conditions: Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression, Anxiety, PTSD
Interventions: Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group; Behavioral
Lead sponsor: University of North Carolina, Charlotte; Other
Eligibility: 18 Years to 99 Years
Enrollment: 141 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Portsmouth, Virginia

Conditions: Psychological Distress, Depression, PTSD, Anxiety
Interventions: Personalized Support for Progress (PSP), Tailored Referral (TR); Other
Lead sponsor: Syracuse VA Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Syracuse, New York • Houston, Texas

Conditions: Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
Interventions: Stepped Care Management; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 14 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression and Quality of Life, Sexual Violence, PTSD, Suicidal Ideation, Problem Drinking
Interventions: Empowerment self-defense training; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Pine Ridge, South Dakota

Conditions: Mental Illness, Burnout Syndrome
Interventions: Not listed
Lead sponsor: Scripps Translational Science Institute; Other
Eligibility: 19 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sleep Disturbance, Sleep, Depression, Suicide
Interventions: TranS-C, Sleep Feedback; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 18 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania

Conditions: Insomnia, Depression, Suicidal Ideation
Interventions: Zolpidem-CR, Placebo; Drug
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 4
States / cities: Augusta, Georgia • Durham, North Carolina • Wake Forest, North Carolina + 1 more

Conditions: Depression, Anxiety, Suicidal Ideation, Eating Disorders
Interventions: Mental Health First Aid; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 2,543 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Search by objective public record fields.

Efficacy of a Multi-level School Intervention for LGBTQ Youth

TMS for Suicidal Crisis in Active Duty SMs

NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young Adults

Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents

Biological Triggers of Depression in Pregnancy

Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality

Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency Department

Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools

Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression

Risperidone and Suicidality in Major Depressive Disorder

Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine

Nurse Suicide: Physiologic Sleep Health Promotion Trial

Screening Wizard- Phase 2

Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses

The Group Risk Reduction Intervention Therapy (GRRIT) Project

Peer Intervention to Improve Access Among Rural Women Veterans With Psychological Distress and Unmet Social Needs

Trauma Survivors Outcomes and Support Study IV

Empowerment Self Defense Program for Adult Native Women Survivors of Sexual Violence

Physician Mental Health Study for Medical Trainees

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

Reducing Suicidal Ideation Through Insomnia Treatment

Mental Health First Aid for College Students