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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Depression in Adolescence Clear all
Completed Not applicable Interventional

Life Experiences in Adolescents and the Development of Skills

NCT04719897
View directory record Official record
Conditions
Depression in Adolescence, Adverse Childhood Experiences
Interventions
FIRST: Repairing Thoughts
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 15 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Jul 21, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

NCT07020572
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Brief Interpersonal Psychotherapy - Adolescent Skills Training (B-IPT-AST), Services as usual (SAU)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional Results available

Video-visit Behavior Therapy for Anxiety and Depression in Youth

NCT05417412
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Brief Behavioral Therapy
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
8 Years to 17 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Jul 21, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional

Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

NCT07155707
View directory record Official record
Conditions
Anxiety, Mood Disorders
Interventions
Teleo, Standard Videoconferencing
Other
Lead sponsor
Stanford University
Other
Eligibility
5 Years to 14 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Monterey, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Phase 4 Interventional

Biomarkers of Antidepressant Treatment in Adolescents With Major Depression (The Adolescents MDD Study)

NCT01185977
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Fluoxetine, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
14 Years to 18 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2014 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Phase 3 Interventional Results available

Lurasidone Pediatric Bipolar Study

NCT02046369
View directory record Official record
Conditions
Bipolar I Depression
Interventions
Lurasidone, Placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
10 Years to 17 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
30
States / cities
Dothan, Alabama • Culver City, California • Hartford, Connecticut + 27 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional

Middle School Matters Study

NCT01220635
View directory record Official record
Conditions
Depression
Interventions
Positive Thoughts and Actions Program, Individual Support Program
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 13, 2014 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Violence Prevention for Adolescent Girls With Prior Maltreatment

NCT02765048
View directory record Official record
Conditions
PTSD, Depression, Aggression, Victimization
Interventions
GAIN Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
3
States / cities
Arnold, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 5, 2016 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Child STEPS for Youth Mental Health in Maine Sustainability

NCT03112304
View directory record Official record
Conditions
Anxiety, Depression, Trauma, Behavior Problems
Interventions
MATCH-ADTC, TRAC
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
6 Years to 15 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional

Shaping Actions and Responses to Emotions

NCT04719949
View directory record Official record
Conditions
Depression in Adolescence, Adverse Childhood Experiences
Interventions
Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 15 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional

Suicide Prevention Among Recipients of Care

NCT04893447
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Suicidal Ideation, Social Support, Secondary Prevention, Patient Care Planning, Outpatients, Outpatient Clinics, Hospital, Mental Health Services, Mental Health, Mental Disorder, Loneliness, Emergency Service, Hospital, Depressive Disorder, Depression, Continuity of Patient Care, Ambulatory Care, Adolescent, Adult, Crisis Intervention
Interventions
SPI+, SP+CC (Caring Contacts)
Behavioral
Lead sponsor
St. Luke's Health System, Boise, Idaho
Other
Eligibility
12 Years and older
Enrollment
1,520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jul 21, 2026, 12:09 PM EDT
Completed No phase listed Observational

Antidepressant Safety in Kids Study

NCT00395213
View directory record Official record
Conditions
Anxiety Disorders, Depressive Disorders, Eating Disorders, Obsessive Compulsive Disorder
Interventions
Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) medications
Drug
Lead sponsor
Duke University
Other
Eligibility
7 Years to 17 Years
Enrollment
569 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Jul 21, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent Encouragement And Coaching of Happiness in Youth

NCT06725160
View directory record Official record
Conditions
Depression, Parent-Child Relations
Interventions
Parent Coaching, Active Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
4 Years to 99 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Addressing Mental Health in African American Job Training Adolescents and Young Adults

NCT00979524
View directory record Official record
Conditions
Depression
Interventions
Comprehensive Mental Health Services and Supports
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 24 Years
Enrollment
782 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2016 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Attention to Emotion Study

NCT04105868
View directory record Official record
Conditions
Depression
Interventions
Neurofeedback
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 15 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Jul 21, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional

Sleep Promotion Program Primary Care

NCT06240325
View directory record Official record
Conditions
Sleep, Sleep Disturbance, Insufficient Sleep
Interventions
SPP, Sleep Psychoeducation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 21, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional

Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention

NCT05748730
View directory record Official record
Conditions
Suicide and Depression, Adolescent Behavior
Interventions
iCHART, Treatment As Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
13
States / cities
Gibbsboro, New Jersey • Johnstown, Pennsylvania • Philadelphia, Pennsylvania + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional

A Mobile Health Solution for Homework During CBT

NCT04931199
View directory record Official record
Conditions
Anxiety, Depression, Posttraumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy (CBT), CBT+App
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Jul 21, 2026, 12:09 PM EDT
Completed No phase listed Observational

Identification of Anxiety and Depression in Adolescents/Young Adults (AYA) With Cancer

NCT04589052
View directory record Official record
Conditions
Cancer, Depression, Anxiety
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 29 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Jul 21, 2026, 12:09 PM EDT
Terminated Not applicable Interventional Results available

rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2

NCT01804296
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Paul E. Croarkin
Other
Eligibility
12 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Phase 1Phase 2 Interventional

Effects of Therapist Behavior on the Treatment of Depressed Adolescents

NCT00073359
View directory record Official record
Conditions
Depression, Depressive Disorder, Dysthymic Disorder
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
13 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Jul 21, 2026, 12:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Efficacy of a Digital Mental Health Intervention for Teen Wildfire Survivors

NCT03868761
View directory record Official record
Conditions
Disaster, PTSD, Adolescent Behavior, Trauma, Anxiety, Stress
Interventions
Sonoma Rises
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 17 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Jul 21, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional

Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior

NCT05652153
View directory record Official record
Conditions
Suicidal Behavior, Suicidal Ideation, Negative Urgency, Cortical Inhibition, Depression
Interventions
Single-/paired-pulse transcranial magnetic stimulation
Other
Lead sponsor
University of Minnesota
Other
Eligibility
13 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Jul 21, 2026, 12:09 PM EDT
Recruiting Not applicable Interventional

Pragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabetes

NCT06618027
View directory record Official record
Conditions
Type 1 Diabetes (T1D)
Interventions
BREATHE-T1D, HealthEd-T1D
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 21, 2026, 12:09 PM EDT