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ClinicalTrials.gov public records Last synced Oct 6, 2026, 7:21 PM EDT

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Showing 121–144 of 266 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression in Adolescence Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression

NCT01829100
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders
Interventions
Group Behavioral Activation Therapy (GBAT)
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
11 Years to 15 Years
Enrollment
895 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 6, 2026, 7:21 PM EDT
Recruiting Not applicable Interventional

Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

NCT07155707
View directory record Official record
Conditions
Anxiety, Mood Disorders
Interventions
Teleo, Standard Videoconferencing
Other
Lead sponsor
Stanford University
Other
Eligibility
5 Years to 14 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Monterey, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Phase 2 Interventional Results available

Study Evaluating Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR) In The Treatment Of Child and Adolescent Outpatients With Major Depressive Disorder

NCT00669110
View directory record Official record
Conditions
Depressive Disorder, Major Depressive Disorder
Interventions
Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR)
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
7 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
9
States / cities
Little Rock, Arkansas • North Miami, Florida • Terre Haute, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional Results available

Cognitive Training Video Game to Target Subclinical Depressive Symptoms in Youth

NCT05697627
View directory record Official record
Conditions
Depression, Subclinical Depressive Symptoms
Interventions
Computerized cognitive training (CCT) using EndeavorRx
Device
Lead sponsor
University of Michigan
Other
Eligibility
9 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Oct 6, 2026, 7:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Resettled Refugee Families for Healing

NCT06176638
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Antisocial Personality Disorder, Anxiety, Aggressive Behavior
Interventions
RRF4H Combination Intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 17 Years
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools

NCT03940508
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
Making Connections Intervention, IPT-A
Behavioral
Lead sponsor
New York University
Other
Eligibility
12 Years to 20 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 6, 2026, 7:21 PM EDT
Recruiting Not applicable Interventional

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function

NCT05691439
View directory record Official record
Conditions
Depression in Adolescence
Interventions
Sleep extension and advance, Regular sleep duration and timing
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
14 Years to 18 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Phase 1 Interventional

Brief Intervention for Suicide Risk Reduction in High Risk Adolescents

NCT02272179
View directory record Official record
Conditions
Adolescent Behavior
Interventions
As Safe As Possible, Brite, Treatment as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 17 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 20, 2018 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional

Implementing an IPTS Treatment Approach to Improve Outcomes in Suicidal Youth

NCT03527459
View directory record Official record
Conditions
Suicidal Ideation, Depression
Interventions
SPARC B, SPARC A
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional

The Impact of an 8-week Supported Exercise Program on Fitness and Symptoms in Adolescents With Down Syndrome

NCT03192540
View directory record Official record
Conditions
Down Syndrome
Interventions
Exercise
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional

Life Experiences in Adolescents and the Development of Skills

NCT04719897
View directory record Official record
Conditions
Depression in Adolescence, Adverse Childhood Experiences
Interventions
FIRST: Repairing Thoughts
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 15 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 6, 2026, 7:21 PM EDT
Recruiting Not applicable Interventional

Enhancing Brain And Mental Health Through Breathing Practice

NCT07369752
View directory record Official record
Conditions
Depressive Disorder, Anxiety, Adolescent
Interventions
Breathing Intervention
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Albert Lea, Minnesota • Eau Claire, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 6, 2026, 7:21 PM EDT
Recruiting Not applicable Interventional

Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth

NCT07364799
View directory record Official record
Conditions
Emotional Dysregulation, Therapeutic Alliance, Depression Disorder, Anxiety Disorders, Stress Disorders, Substance Use Disorders, Mental Health Disorders
Interventions
Multi-sensory emotional regulation intervention (Heal)
Behavioral
Lead sponsor
SoundHeal
Industry
Eligibility
12 Years to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional

Brief Cognitive Behavioral Therapy (CBT) for Pediatric Anxiety and Depression in Primary Care

NCT01147614
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Brief Cognitive Behavioral Therapy (BCBT), Specialty mental health care referral (SMHC)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
8 Years to 16 Years
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
San Diego, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Oct 6, 2026, 7:21 PM EDT
Terminated Not applicable Interventional

Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology

NCT05461599
View directory record Official record
Conditions
Depressive Symptoms, Major Depressive Disorder, Depression, Cardiology, Gastrointestinal Diseases, Depressive Disorder, Depressive Episode, Adolescent Behavior, Adolescent - Emotional Problem
Interventions
SparkRx Mobile App
Device
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
13 Years to 22 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional

The Impact of a School-Based, Trauma-Informed CBT Intervention for Young Women

NCT03376633
View directory record Official record
Conditions
Anxiety, Anxiety Disorders, Behavioral Symptoms, Depression, Mental Disorders, Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Trauma and Stressor Related Disorders, Wounds and Injuries
Interventions
Working on Womanhood (WOW)
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
Female only
Enrollment
5,106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional

Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2

NCT05267340
View directory record Official record
Conditions
Depression Mild, Depression Moderate, Depression, Teen
Interventions
TARA, Psycho-Education
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
14 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 6, 2026, 7:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Families and Middle School Success Project

NCT05400564
View directory record Official record
Conditions
Parenting, Parent-Child Relations, Self-regulation, Problem Behavior in School, School Adjustment, Depression
Interventions
Family Check-Up
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 6, 2026, 7:21 PM EDT
Not listed Not applicable Interventional

N-acetylcysteine in the Treatment of Depressive Symptoms in Bipolar Offspring

NCT02865629
View directory record Official record
Conditions
Depression
Interventions
N-acetyl cysteine
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
15 Years to 24 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Oct 6, 2026, 7:21 PM EDT
Completed No phase listed Observational

Brain Function in Mentally Ill Adolescents

NCT00025857
View directory record Official record
Conditions
Healthy, Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
7 Years to 18 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Oct 6, 2026, 7:21 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Online System for Identifying and Addressing Teen Depression in Primary Care

NCT04489485
View directory record Official record
Conditions
Major Depression, Dysthymia, Depressive Symptoms
Interventions
Teen Depression Module used for care
Behavioral
Lead sponsor
Total Child Health, Inc.
Industry
Eligibility
12 Years to 99 Years
Enrollment
580 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 6, 2026, 7:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Study Examining Adolescents With Non-Suicidal Self-Injury

NCT02947308
View directory record Official record
Conditions
Self-Injurious Behavior, Deliberate Self-Harm
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 16 Years · Female only
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
3
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 6, 2026, 7:21 PM EDT
Completed Not applicable Interventional Results available

Text-Message-Based Depression Prevention for High-Risk Youth in the ED

NCT02332239
View directory record Official record
Conditions
Depressive Disorder, Violence
Interventions
iDOVE Intervention (ED+text), Control (EUC)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 6, 2026, 7:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The PATHway Study: Primary Care Based Depression Prevention in Adolescents

NCT05203198
View directory record Official record
Conditions
Depression, Mental Disorder in Adolescence
Interventions
Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
13 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
6
States / cities
Chicago, Illinois • Glenview, Illinois • Park Ridge, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 6, 2026, 7:21 PM EDT