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ClinicalTrials.gov public records Last synced Oct 9, 2026, 1:14 AM EDT

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Showing 145–168 of 266 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression in Adolescence Clear all
Completed Phase 3 Interventional Results available

A Study in the Treatment of Children and Adolescents With Major Depressive Disorder

NCT00849901
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
duloxetine, Placebo, fluoxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
7 Years to 17 Years
Enrollment
337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
24
States / cities
Costa Mesa, California • Irvine, California • Palo Alto, California + 21 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression

NCT01829100
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders
Interventions
Group Behavioral Activation Therapy (GBAT)
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
11 Years to 15 Years
Enrollment
895 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 9, 2026, 1:14 AM EDT
Not listed Phase 4 Interventional

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

NCT04245436
View directory record Official record
Conditions
Anxiety, Depressive Symptoms
Interventions
Duloxetine, Escitalopram
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implementing and Evaluating an Internet-based Cognitive Behavior Therapy Intervention in School Settings

NCT04928001
View directory record Official record
Conditions
Depression Anxiety and Co-occurring Rural Youth
Interventions
internet based iCBT program, Youth Thrive
Other
Lead sponsor
Montana State University
Other
Eligibility
13 Years to 19 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Jan 30, 2025 · Synced Oct 9, 2026, 1:14 AM EDT
Terminated Phase 1 Interventional

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

NCT04951609
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Seltorexant, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
12 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
12
States / cities
Phoenix, Arizona • Anaheim, California • San Diego, California + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Phase 1Phase 2 Interventional

The Efficacy of Parent Involvement in the Treatment of Adolescent Depression

NCT00883519
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder NOS, Adjustment Disorder
Interventions
Interpersonal Psychotherapy for Depressed Adolescents, Interpersonal Psychotherapy for Depressed Adolescents and Parents
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2012 · Synced Oct 9, 2026, 1:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bone Mineral Content and Bone Metabolism in Adolescents on Antipsychotic Therapy

NCT00399776
View directory record Official record
Conditions
Adolescent Depression
Interventions
Bone Density Test
Radiation
Lead sponsor
Creighton University
Other
Eligibility
10 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 4, 2011 · Synced Oct 9, 2026, 1:14 AM EDT
Completed No phase listed Observational

A Retrospective Study to Evaluate NeuroStar® Advanced Therapy in Adolescents

NCT06699940
View directory record Official record
Conditions
MDD
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Neuronetics
Other
Eligibility
12 Years to 21 Years
Enrollment
7,690 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Malvern, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sexual and Gender Minority Youth (SGMY) and Online Interventions to Increase Help-seeking for Anxiety and/or Depression

NCT06083987
View directory record Official record
Conditions
Anxiety, Depression, Adolescent Behavior, Sexual and Gender Minorities
Interventions
Intersectionality and Identity, Confidentiality, Educating Your Community, How to find Affirming Caregivers, Control Group - No Interventions
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 19 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 9, 2026, 1:14 AM EDT
Terminated Not applicable Interventional Results available

Comparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With Depression

NCT01740726
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Behavioral Activation, Fluoxetine
Behavioral · Drug
Lead sponsor
Emory University
Other
Eligibility
13 Years to 17 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 20, 2017 · Synced Oct 9, 2026, 1:14 AM EDT
Enrolling by invitation No phase listed Observational

Social Media Concerns Related to Emotional Experiences in Naturalistic Settings (SCREENS)

NCT07278752
View directory record Official record
Conditions
Depression in Adolescence, Suicidal Ideation, Social Media Addiction, Mental Health Issue
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
13 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional

Shaping Actions and Responses to Emotions

NCT04719949
View directory record Official record
Conditions
Depression in Adolescence, Adverse Childhood Experiences
Interventions
Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 15 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Trauma-Informed Intervention for Positive Youth Development and Teacher Wellness in Rural Montana

NCT05085392
View directory record Official record
Conditions
Depression, Anxiety, Stress
Interventions
Trauma-Informed Yoga
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Livingston, Montana
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Phase 3 Interventional Results available

A 6-Month Open-Label Extension Study to the B2061014 Study to Evaluate the Safety, Tolerability and Efficacy of DVS SR in the Treatment of Children and Adolescents With MDD

NCT01371721
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
DVS SR
Drug
Lead sponsor
Pfizer
Industry
Eligibility
7 Years to 17 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
33
States / cities
Dothan, Alabama • Goodyear, Arizona • Tucson, Arizona + 26 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Oct 9, 2026, 1:14 AM EDT
Active, not recruiting Not applicable Interventional

Suubi-Mhealth: A Mobile Health Intervention to Address Depression Among Youth

NCT05965245
View directory record Official record
Conditions
Depression, HIV Infection
Interventions
Suubi-Mhealth
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 17 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 9, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

NCT07155707
View directory record Official record
Conditions
Anxiety, Mood Disorders
Interventions
Teleo, Standard Videoconferencing
Other
Lead sponsor
Stanford University
Other
Eligibility
5 Years to 14 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Monterey, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 9, 2026, 1:14 AM EDT
Recruiting Phase 2 Interventional

Adolescent Chatbot

NCT07094503
View directory record Official record
Conditions
Body Image Disturbance, Disordered Eating Behaviors, Eating Disorder Prevention
Interventions
Wysa Digital Chatbot Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
13 Years to 19 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 9, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Behavioral Activation for Treatment of Depression in Autistic Adolescents With Below Average Intelligence

NCT07812870
View directory record Official record
Conditions
Autism, Depressed, Depressed Mood
Interventions
BA-A
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
12 Years to 17 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth

NCT02553161
View directory record Official record
Conditions
Depression, Anxiety, Bipolar Disorder
Interventions
Escitalopram, Cognitive behavioral Psychotherapy
Drug · Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Stanford, California • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 26, 2024 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Results available

Study of Repetitive Transcranial Magnetic Stimulation (rTMS) in Depressed Teens

NCT01502033
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Paul E. Croarkin
Other
Eligibility
13 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2016 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Phase 1 Interventional

Brief Intervention for Suicide Risk Reduction in High Risk Adolescents

NCT02272179
View directory record Official record
Conditions
Adolescent Behavior
Interventions
As Safe As Possible, Brite, Treatment as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 17 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 20, 2018 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prevention of Substance Use in At-Risk Students: A Family-Centered Web Program

NCT03060291
View directory record Official record
Conditions
Substance Use, Conduct Disorders in Adolescence, Depression, Anxiety
Interventions
FCU-Online, web/ mobile only, FCU-Online, web/ mobile + coach
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Not listed
Enrollment
322 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Bupropion for Treating Nicotine Dependence in Young People

NCT00129272
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
Bupropion-SR, Placebo
Drug · Other
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
12 Years to 25 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Oct 9, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Violence Prevention for Adolescent Girls With Prior Maltreatment

NCT02765048
View directory record Official record
Conditions
PTSD, Depression, Aggression, Victimization
Interventions
GAIN Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
3
States / cities
Arnold, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 6, 2016 · Synced Oct 9, 2026, 1:14 AM EDT