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ClinicalTrials.gov public records Last synced Sep 30, 2026, 10:48 PM EDT

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Showing 49–72 of 1,320 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depressive; Behavioral Disorder Clear all
Completed Not applicable Interventional

A Clinical Trial for the Treatment of Depression With Repetitive Transcranial Magnetic Stimulation (rTMS)

NCT01909232
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Active Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator, Inactive Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator
Device
Lead sponsor
Cervel Neurotech, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
6
States / cities
Atlanta, Georgia • Baltimore, Maryland • Lebanon, New Hampshire + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2016 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional

Adapting Cognitive Behavioral Therapy (CBT) for Chinese Americans

NCT01786746
View directory record Official record
Conditions
Major Depression
Interventions
cognitive behavioral therapy, culturally adapted cognitive behavioral therapy
Behavioral
Lead sponsor
Claremont McKenna College
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Claremont, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2013 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain Imaging of rTMS Treatment for Depression

NCT01829165
View directory record Official record
Conditions
Major Depressive Disorder, Depression
Interventions
rTMS Treatment, Sham rTMS Treatment
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 50 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 30, 2026, 10:48 PM EDT
Not yet recruiting Not applicable Interventional

The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment

NCT07415850
View directory record Official record
Conditions
IVF, In Vitro Fertilization, Quality of Life (QOL), Anxiety, Depression and Anxiety Symptom, Assisted Reproduction Technologies, Yoga, Mental Health
Interventions
Yoga
Behavioral
Lead sponsor
Villanova University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Villanova, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional

Treatment for Depressed, Obese Individuals at Risk for Cardiovascular Disease (CVD)

NCT01692574
View directory record Official record
Conditions
Obesity, Major Depressive Disorder, Dysthymic Disorder, Cardiovascular Disease
Interventions
Behavior Modification for Weight Loss, Alternative Approach to Weight Loss, Cognitive-Behavior Therapy for Depression, Depression Support and Education
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2016 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional

Family Cognitive Behavioral Therapy for Preventing Depression in Children

NCT00183482
View directory record Official record
Conditions
Depression
Interventions
Family Group Cognitive Behavioral, Written Information
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
9 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PET Imaging of mGLuR5 With Drug Challenge

NCT01691092
View directory record Official record
Conditions
Major Depressive Disorder, Post-Traumatic Stress Disorder (PTSD)
Interventions
Ketamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Sep 30, 2026, 10:48 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Beyond Listening: A Music-based Intervention

NCT04840173
View directory record Official record
Conditions
Alzheimer's Disease (Incl Subtypes), Depressive Symptoms
Interventions
Music
Behavioral
Lead sponsor
MJHS Institute for Innovation in Palliative Care
Other
Eligibility
Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Sep 30, 2026, 10:48 PM EDT
Enrolling by invitation Not applicable Interventional

Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder

NCT06572683
View directory record Official record
Conditions
MDD, Depression
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 75 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Enhancing Cognition in Older Adults

NCT03653351
View directory record Official record
Conditions
Cognitive Impairment, Mild, Depressive Symptoms, Anxiety
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Sep 30, 2026, 10:48 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

NCT05552053
View directory record Official record
Conditions
Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk, Depression, Depression, Postpartum, Perinatal Depression, Anxiety, Anxiety in Pregnancy, Stress, Psychological, Racism, Discrimination, Racial, Inflammation
Interventions
MWSH plus Candlelit Care, MWSH
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Sep 30, 2026, 10:48 PM EDT
Terminated Phase 2Phase 3 Interventional

A Health Intervention to Prevent Depression Hepatitis C Patients

NCT01890083
View directory record Official record
Conditions
Hepatitis C, Major Depressive Disorder
Interventions
Exercise, Health Education
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality Behavioral Activation: An Intervention for Major Depressive Disorder

NCT04268316
View directory record Official record
Conditions
Major Depressive Disorder, MDD, Depression
Interventions
Virtual Reality Behavioral Activation, Behavioral Activation in real-life
Device · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Sep 30, 2026, 10:48 PM EDT
Terminated Phase 3 Interventional Results available

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

NCT01111552
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Escitalopram, Aripiprazole, Placebo
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
20
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Carson, California + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Phase 2 Interventional Results available

Ketamine Plus Lithium in Treatment-Resistant Depression

NCT01880593
View directory record Official record
Conditions
Depression
Interventions
Lithium, Ketamine, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
21 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2018 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Phase 4 Interventional

Safety and Efficacy of Vilazodone in Major Depressive Disorder

NCT01573598
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Placebo, Vilazodone
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 70 Years
Enrollment
1,219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
38
States / cities
Beverly Hills, California • Chino, California • Costa Mesa, California + 32 more
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional

Online Cognitive Behavioral Therapy for Depressive Symptoms in Rural Patients with Cardiac Disease

NCT04986969
View directory record Official record
Conditions
Depressive Symptoms, Heart Diseases
Interventions
Online cognitive behavioral therapy
Behavioral
Lead sponsor
Debra Moser
Other
Eligibility
21 Years to 110 Years
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Phase 2 Interventional

An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression

NCT00070694
View directory record Official record
Conditions
Depressive Disorder
Interventions
MDL100.907
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

CBT+ for Depression

NCT06001346
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
ActiveCBT, CalmCBT
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 30, 2026, 10:48 PM EDT
Recruiting Phase 2 Interventional

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

NCT07610473
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
DT-101, Placebo
Drug
Lead sponsor
Draig Therapeutics Ltd
Industry
Eligibility
18 Years to 75 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
23
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Bellflower, California + 17 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 30, 2026, 10:48 PM EDT
Suspended No phase listed Observational Accepts healthy volunteers

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

NCT04031469
View directory record Official record
Conditions
Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder, Autism Spectrum Disorder High-Functioning, Alzheimer Disease, Alzheimer Dementia (AD), Alzheimer Dementia, Alzheimer Disease (AD), Crohn, Crohn Colitis, Crohn Disease (CD), Crohn Disease Colon, Myalgic Encephalomyelitis, ME/CFS, Myalgic Encephalomyelitis (ME), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Psoriasis, Psoriasis Annularis, Psoriasis Chronic, Chronic Urinary Tract Infection, Ulcerative Colitis (Disorder), Ulcerative Colitis (UC), Ulcerative Colitis Acute, Ulcerative Colitis Chronic, Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Constipation Chronic Idiopathic, Constipation, Celiac, Celiac Disease, Celiac Sprue, Lyme Arthritis, Lyme Borreliosis, Nervous System, Lyme Disease, Chronic, Cholesterol, Cholesterol Level, High, Cancer, Colon Cancer, Amyotrophic Lateral Sclerosis (ALS), Amyotrophic Lateral Sclerosis, Rheumatoid Arthritis (RA), Rheumatoid Arthritis - Rheumatism, Chronic Fatigue Syndrome (CFS), PARKINSON DISEASE (Disorder), Parkinson Disease, Parkinson Disease (PD), Depression, Major Depressive Disorder (MDD), Depression Disorder, Depression in Adults, Anxiety, Anxiety Disorder Generalized, Obsessive Compulsive Disorder (OCD), Obsessive Compulsive Disorder OCD, Obsessive - Compulsive Disorder, Bipolar, Bipolar 1 Disorder, Bipolar Disorder (BD), Bipolar Disorder I and II, Bipolar and Related Disorders, Migraine, Migraine Disorder, Diabetes (DM), Diabetes, Lupus, Lupus Erythematosus, Epidermolysis Bullosa (EB), Mesothelioma, Mesothelioma Malignant, IBS (Irritable Bowel Syndrome), Irritable Bowel, IBS - Irritable Bowel Syndrome, Irritable Bowel Syndrome (IBS), Eczema, Eczema Atopic Dermatitis, Acne, Myasthaenia Gravis, Gout
Interventions
There is no intervention in this study
Other
Lead sponsor
ProgenaBiome
Other
Eligibility
12 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2030
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Cranial Electrotherapy Stimulation for the Treatment of Major Depressive Disorder in Adults

NCT05384041
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Fisher Wallace Cranial Electrotherapy Stimulator (Active Device), Fisher Wallace Cranial Electrotherapy Stimulator (Placebo Device)
Device
Lead sponsor
Fisher Wallace Laboratories
Industry
Eligibility
21 Years to 65 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Imaging Predictors of Treatment Response in Depression

NCT00367341
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
escitalopram, Cognitive Behavioral Therapy (CBT)
Drug · Behavioral
Lead sponsor
Emory University
Other
Eligibility
21 Years to 60 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 9, 2014 · Synced Sep 30, 2026, 10:48 PM EDT
Completed Phase 4 Interventional

Electroencephalography (EEG) Biomarkers of Response in Depression

NCT00759122
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
venlafaxine (Effexor), placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2008 · Synced Sep 30, 2026, 10:48 PM EDT