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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Supplemental Oxygen and Oxygen Desaturations in Colonoscopies

NCT07515755
Conditions
Oxygen Desaturation, Apnea (Central and Obstructive), Airway Obstruction
Interventions
Breath-synchronized oxygen, CPAP, Control
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
South Jordan, Utah
Conditions
Response of Fatty Acid Desaturation to Zinc Intake
Interventions
30 mg Zn Amino Acid daily for 13 days, 30 mg Zn Gluconate daily for 13 days
Dietary Supplement
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Berkeley, California
Conditions
Neonatal Respiratory Failure, Tracheal Intubation Morbidity
Interventions
Apneic Oxygenation, Standard of Care
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
0 Days to 365 Days
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Cardiovascular Disease, Surgery
Interventions
Quality improvement intervention
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
40 Years to 89 Years
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
3
States / cities
Portland, Maine • Lebanon, New Hampshire • Manchester, New Hampshire
Conditions
Sickle Cell Disease
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Completed No phase listed Observational Accepts healthy volunteers

Controlled Desaturation Study for TipTraQ SpO2 Performance Validation

NCT06634693
Conditions
Hypoxia
Interventions
Not listed
Lead sponsor
PranaQ Pte. Ltd.
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Suspended Not applicable Interventional Accepts healthy volunteers

Alternate Methodology of Pulse Oximeter Validation

NCT03628560
Conditions
Hypoxemia, Desaturation of Blood
Interventions
RespirAct Step-Wise Normocapnia desaturation sequence, RespirAct Slope Normocapnia desaturation sequence, RespirAct Step-Wise Hypocapnia desaturation sequence, RespirAct Slope Hypocapnia desaturation sequence, ROBD Step-Wise desaturation sequence
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Conscious Sedation, Bronchoscopy
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea, High Flow Nasal Cannula
Interventions
The Comfort Flo system, The Salter nasal cannula
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Conditions
ESRD, Sleep Apnea, Oxygen Deficiency
Interventions
Observational
Other
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Airway Obstruction, Apnea, Hypopnea
Interventions
Airway Management System (AMS)
Device
Lead sponsor
5i Sciences, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
La Jolla, California
Conditions
Congenital Heart Disease, Desaturation of Blood
Interventions
VITLS Device
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 1 Year
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Not listed
Lead sponsor
VA New York Harbor Healthcare System
Federal
Eligibility
45 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Conditions
Desaturation of Blood, Colonoscopy
Interventions
Salter nasal cannula, Face mask, High Flow Nasal Cannula
Other · Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Completed No phase listed Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00006

NCT03435211
Conditions
Healthy
Interventions
INVSENSOR00006
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Conditions
Congenital Disorders, Cerebral Desaturation, Neonatal Surgery
Interventions
NIRS/EEG monitoring
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 60 Weeks
Enrollment
900 participants
Timeline
2022 – 2027
U.S. locations
4
States / cities
New York, New York • Philadelphia, Pennsylvania • Dallas, Texas + 1 more
Completed Phase 3 Interventional Results available

Long-term Oxygen Treatment Trial

NCT00692198
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Supplemental oxygen therapy
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
40 Years and older
Enrollment
738 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
39
States / cities
Birmingham, Alabama • Duarte, California • Loma Linda, California + 30 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00009

NCT03396835
Conditions
Healthy
Interventions
INVSENSOR00009
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Irvine, California
Conditions
Renal Disease, Hypoxia
Interventions
Not listed
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years and older
Enrollment
5,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Conditions
Sleep Disordered Breathing, Nocturnal Oxygen Desaturation, Upper Airway Edema
Interventions
Forty-five degrees elevated upper body position, non-elevated upper body position, Noninvasive wrist pulse oximeter (WristOx Model 3150), Stop-Bang questionnaire, Epworth Sleepiness Scale, P-SAP Score, self-reported pain
Procedure · Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Cerebral Ischemia
Interventions
Hypocapnic group, Normocapnic group
Other
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Evanston, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00031

NCT03783780
Conditions
Healthy
Interventions
INVSENSOR00031
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Conditions
Apnea of Prematurity, Desaturation of Blood, Central Apnea, Periodic Breathing, Obstructive Apnea of Newborn
Interventions
Targeting SpO2 at 93-95%, Targeting SpO2 at 90-92%
Other
Lead sponsor
University of Miami
Other
Eligibility
Up to 18 Weeks
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00038

NCT04017611
Conditions
Healthy
Interventions
INVSENSOR00038
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California