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ClinicalTrials.gov public records Last synced Sep 11, 2026, 4:52 PM EDT

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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Desaturation Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

NCT07573150
View directory record Official record
Conditions
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
Interventions
Infrared Pupillometry
Device
Lead sponsor
NeurOptics Inc
Industry
Eligibility
3 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Francisco, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Interventional Results available

Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients

NCT03021551
View directory record Official record
Conditions
Morbid Obesity, Surgery
Interventions
Rainbow sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Phase 3 Interventional Results available

Long-term Oxygen Treatment Trial

NCT00692198
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Supplemental oxygen therapy
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
40 Years and older
Enrollment
738 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
39
States / cities
Birmingham, Alabama • Duarte, California • Loma Linda, California + 30 more
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

SpO2 Accuracy Low Saturation Validation of the OxySoftN Sensor

NCT04811963
View directory record Official record
Conditions
Hypoxia, Desaturation of Blood
Interventions
Non-Invasive Controlled Hypoxia
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional

Providing Oxygen During Intubation in the NICU Trial

NCT05451953
View directory record Official record
Conditions
Neonatal Respiratory Failure, Tracheal Intubation Morbidity
Interventions
Apneic Oxygenation, Standard of Care
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
0 Days to 365 Days
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 11, 2026, 4:52 PM EDT
Withdrawn Phase 4 Interventional

Ranolazine Versus Placebo Effects on Exercise Tolerance in Patients With Heart Disease and Peripheral Arterial Disease

NCT00657514
View directory record Official record
Conditions
Peripheral Arterial Disease, Angina
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
Colorado Prevention Center
Other
Eligibility
40 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 14, 2014 · Synced Sep 11, 2026, 4:52 PM EDT
Not listed No phase listed Observational

Identification of Desaturation Episodes by Means of Continuous Measurement of Oxygen Saturation During Hemodialysis

NCT02987179
View directory record Official record
Conditions
ESRD, Sleep Apnea, Oxygen Deficiency
Interventions
Observational
Other
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional

Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants

NCT03695900
View directory record Official record
Conditions
Apnea of Prematurity, Desaturation of Blood, Central Apnea, Periodic Breathing, Obstructive Apnea of Newborn
Interventions
Targeting SpO2 at 93-95%, Targeting SpO2 at 90-92%
Other
Lead sponsor
University of Miami
Other
Eligibility
Up to 18 Weeks
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

NCT03430206
View directory record Official record
Conditions
Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
Interventions
High-flow nasal cannula
Device
Lead sponsor
Stanford University
Other
Eligibility
Up to 18 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00028

NCT03704636
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00028
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Philps FAST2022 picoSAT Pulse Oximetry Desaturation Study

NCT05683366
View directory record Official record
Conditions
SpO2 (Peripheral Oxygen Saturation) Measurement Validation
Interventions
No Intervention
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 50 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional

Peripheral Nerve Stimulation to Reduce Hypoxic Events

NCT02554110
View directory record Official record
Conditions
Apnea, Hypoventilation, Hypoxemia
Interventions
Stimulator active device, Stimulator sham Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional

Evaluation of VITLS Compared to Traditional Inpatient Monitoring in Cardiac Shunt-Dependent Children

NCT05526768
View directory record Official record
Conditions
Congenital Heart Disease, Desaturation of Blood
Interventions
VITLS Device
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 1 Year
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Sep 11, 2026, 4:52 PM EDT
Not listed Not applicable Interventional

SuperNO2VA™ and General Anesthesia Postoperative Care

NCT03969615
View directory record Official record
Conditions
Hypoxemia, Acute Respiratory Failure
Interventions
SuperNO2VA nasal positive airway pressure devic, Supplemental oxygen
Device
Lead sponsor
Vyaire Medical
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2019 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00039

NCT04112784
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00039
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Observational

Oxygen Desaturation During Hemodialysis

NCT02501044
View directory record Official record
Conditions
Renal Disease, Hypoxia
Interventions
Not listed
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years and older
Enrollment
5,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2015 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study

NCT04559763
View directory record Official record
Conditions
Hypoxia, Desaturation of Blood
Interventions
Non-Invasive Controlled Hypoxia, Introduction of Motion conditions: tapping or rubbing
Device · Other
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Observational

NTX Wireless Patient Monitoring System

NCT00654693
View directory record Official record
Conditions
Desaturation, Bradycardia, Tachycardia, Hypertension, Hypotension
Interventions
Rapid Response Team
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 6, 2012 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00036

NCT04002960
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00036
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Observational

Identification of Oxygen Desaturation in Patients Admitted Following Adenotonsillectomy'

NCT06512285
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Continuous Pulse Oximetry
Diagnostic Test
Lead sponsor
Baylor College of Medicine
Other
Eligibility
1 Year and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 11, 2026, 4:52 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Alternate Methodology of Pulse Oximeter Validation

NCT03628560
View directory record Official record
Conditions
Hypoxemia, Desaturation of Blood
Interventions
RespirAct Step-Wise Normocapnia desaturation sequence, RespirAct Slope Normocapnia desaturation sequence, RespirAct Step-Wise Hypocapnia desaturation sequence, RespirAct Slope Hypocapnia desaturation sequence, ROBD Step-Wise desaturation sequence
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 11, 2026, 4:52 PM EDT
Completed Not applicable Interventional Results available

High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients

NCT03148262
View directory record Official record
Conditions
Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea, High Flow Nasal Cannula
Interventions
The Comfort Flo system, The Salter nasal cannula
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2018 · Synced Sep 11, 2026, 4:52 PM EDT
Not listed Not applicable Interventional

HFNC Versus Conventional Nasal Cannula in Oxygen Performance in Patients Receiving Colonoscopy Under IV Sedation

NCT02968706
View directory record Official record
Conditions
Desaturation of Blood
Interventions
High Flow Nasal Cannula, Conventional Nasal Cannula, Patient satisfaction questionnaire
Device · Other
Lead sponsor
Aventura Hospital and Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Feb 19, 2017 · Synced Sep 11, 2026, 4:52 PM EDT
Completed No phase listed Observational

Redesigning Cardiac Surgery to Reduce Neurologic Injury

NCT00432536
View directory record Official record
Conditions
Cardiovascular Disease, Surgery
Interventions
Quality improvement intervention
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
40 Years to 89 Years
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
3
States / cities
Portland, Maine • Lebanon, New Hampshire • Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 15, 2013 · Synced Sep 11, 2026, 4:52 PM EDT