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Showing 1–24 of 97 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Developmental Language Disorder and Language Impairment Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Framework For Linking Sequential Pattern Rules in DLD: Perception in Toddlers

NCT04531514
View directory record Official record
Conditions
Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
Interventions
Sensitivity to phonological rules & referents OR: Toddlers, Sensitivity to phonological rules & referents FR: Toddlers
Other
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
19 Months to 36 Months
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter

NCT06181149
View directory record Official record
Conditions
Healthy Subjects, Stuttering, Developmental
Interventions
Delaying speech initiation, Auditory errors and pre-speech auditory modulation, Contributions of the speech premotor cortex to pre-speech auditory modulation, Delaying auditory feedback
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
3 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Tempe, Arizona • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Enrolling by invitation No phase listed Observational

Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years

NCT07521371
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language, Autism Spectrum Disorder With Impaired Functional Language, Autistic Disorder of Childhood Onset With Full Syndrome, Autistic Disorders Spectrum, Autistic Disorder, Autistic Disorder in Children and Adolescents, Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities
Interventions
Not listed
Lead sponsor
Healing Hope International
Other
Eligibility
4 Years to 21 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Spring, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Development of Stuttering in Young Children

NCT06578416
View directory record Official record
Conditions
Stuttering, Stuttering, Childhood, Stuttering, Developmental
Interventions
Standardized assessments of speech and language abilities
Diagnostic Test
Lead sponsor
Michigan State University
Other
Eligibility
3 Years to 6 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Semantic Learning Deficits in School Age Children With Developmental Language Disorder

NCT04508699
View directory record Official record
Conditions
Developmental Language Disorder
Interventions
semantic learning
Other
Lead sponsor
San Diego State University
Other
Eligibility
10 Years to 12 Years
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech

NCT05437159
View directory record Official record
Conditions
Stuttering, Developmental, Aphasia, Primary Progressive
Interventions
Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords, Anodal tDCS, Sham tDCS, Learning of non-native phoneme combinations: 8 training sessions
Behavioral · Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
6 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Active, not recruiting Phase 2 Interventional

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

NCT04060017
View directory record Official record
Conditions
Autism Spectrum Disorder, Language Disorders
Interventions
Levoleucovorin Calcium, Placebo
Drug · Other
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
30 Months to 60 Months
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Not listed Not applicable Interventional

Reading Remediation and Outcomes in Detention

NCT03261076
View directory record Official record
Conditions
Specific Learning Disorder (MeSH Unique ID: D000067559), Dyslexia (MeSH Unique ID: D004410), Conduct Disorder (MeSH Unique ID: D019955)
Interventions
Strategies Enhancing Reading in Older Underperf. Students
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
14 Years to 16 Years · Male only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Jul 21, 2026, 6:07 PM EDT
Not listed Not applicable Interventional

Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT)

NCT03773406
View directory record Official record
Conditions
Aphasia
Interventions
Offline tDCS-before therapy, Sham tDCS, Offline tDCS-after therapy, Online tDCS
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Jul 21, 2026, 6:07 PM EDT
Not listed Not applicable Interventional

Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia

NCT00068835
View directory record Official record
Conditions
Developmental Dyslexia
Interventions
Lindamood-Bell training for dyslexia
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
8 Years to 12 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Recasting or Book Reading by Parents or Clinicians

NCT05099328
View directory record Official record
Conditions
Developmental Language Disorder and Language Impairment
Interventions
Recast Therapy, Syntax Stories
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
4 Years to 9 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Newark, Delaware • College Park, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Suspended Phase 3 Interventional Accepts healthy volunteers

A Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Tolerability of Asenapine With Flexible Dosing From 5mg to 20mg in Adults With Developmental Stuttering

NCT01684657
View directory record Official record
Conditions
Stuttering
Interventions
Asenapine
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Influence of Immersive Virtual Field Trips on Academic Vocabulary

NCT05242575
View directory record Official record
Conditions
Developmental Language Disorder, Language Disorders in Children
Interventions
The information provided in the iVFT and control book parallel one another.
Behavioral
Lead sponsor
Salus University
Other
Eligibility
6 Years to 8 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Strategies for Teaching Verbs

NCT03441685
View directory record Official record
Conditions
Language Development Disorders, Down Syndrome, Child Language
Interventions
Semantic cues (perform action), syntactic cues (sentence frame), or combined semantic and syntactic cues
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
3 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Active, not recruiting Not applicable Interventional

Evaluation of an Explicit Approach

NCT04902508
View directory record Official record
Conditions
Developmental Language Disorder, Explicit Intervention, Grammatical Language
Interventions
Implicit-only, Explicit-added
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
5 Years to 9 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

NCT07459803
View directory record Official record
Conditions
Stuttering, Developmental, Dyslexia, Healthy Participants
Interventions
Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation, Sustained F0 auditory feedback perturbation, Reflexive somatosensory perturbation, Anodal tCS targeting pSTG and vSSC, Anodal tCS targeting left or right vPMC, Sham tCS targeting pSTG or vSSC, Sham tCS targeting left vPMC or right vPMC
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of Normative Ultrasound Databases of Tongue Surface Configuration

NCT00001218
View directory record Official record
Conditions
Healthy, Speech Disorders
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1987 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading

NCT06026124
View directory record Official record
Conditions
Developmental Language Disorder, Specific Language Impairment, Language Development
Interventions
Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
48 Months to 71 Months
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Indianapolis, Indiana • West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Kindergarten Children Acquiring Words Through Storybook Reading

NCT03586479
View directory record Official record
Conditions
Language Development Disorders
Interventions
Interactive storybook reading
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
5 Years to 6 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Manipulating Linguistic Complexity to Improve Child Language Treatment Outcomes

NCT03977701
View directory record Official record
Conditions
Language Development Disorders, Speech Sound Disorder
Interventions
Phonological treatment, Morpheme treatment
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
3 Years to 6 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Training Inner Speech in Children With Developmental Language Disorder

NCT06880731
View directory record Official record
Conditions
Developmental Language Disorder
Interventions
Modeling with Verbal Mediation, Modeling Only
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
8 Years to 10 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Maximizing Outcomes for Preschoolers With Developmental Language Disorders

NCT03782493
View directory record Official record
Conditions
Developmental Language Disorder
Interventions
the Enhanced Milieu Teaching-Sentence Focus
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
27 Months to 31 Months
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Evanston, Illinois • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting No phase listed Observational

FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

NCT03718923
View directory record Official record
Conditions
FOXP1, Mental Retardation With Language Impairment and With or Without Autistic Features, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
2 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Early School Readiness in Primary Health Care

NCT00212576
View directory record Official record
Conditions
Language Development Disorders
Interventions
Video Interaction Project, Building Blocks Project
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Weeks and older
Enrollment
675 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2019 · Synced Jul 21, 2026, 6:07 PM EDT