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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Diabetes Prevention Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Modification for Type 2 Diabetes Prevention in Overweight Youth

NCT01610219
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Lifestyle Modification for Type 2 Diabetes Prevention, Nutrition and Physical Activity
Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
4 Years to 8 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Jun 10, 2026, 5:43 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes

NCT06948825
View directory record Official record
Conditions
Weight Loss, Gestational Diabetes Mellitus in Pregnancy, Postpartum Care
Interventions
Metformin Hcl 850Mg Tab, Lifestyle Intervention, Enhanced Lifestyle Intervention
Drug · Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluating Tools for Health Promotion and Disease Prevention

NCT00164658
View directory record Official record
Conditions
Coronary Heart Disease, Stroke, Diabetes, Breast Cancer, Ovarian Cancer, Colorectal Cancer
Interventions
Familial risk assessment and personalized prevention messages
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
35 Years to 65 Years
Enrollment
8,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
3
States / cities
Evanston, Illinois • Leawood, Kansas • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 6, 2010 · Synced Jun 10, 2026, 5:43 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Pilot Study of Nocturnal Hypoglycemia Prevention in Type 1 Diabetes Using the Vigilant Diabetes Management Companion

NCT02906891
View directory record Official record
Conditions
Hypoglycemia, Diabetes Mellitus, Type 1
Interventions
Vigilant Diabetes Management Application
Device
Lead sponsor
InSpark Technologies, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 2, 2017 · Synced Jun 10, 2026, 5:43 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Social Determinants and a Diabetes Prevention Program Tailored for African Americans

NCT05301413
View directory record Official record
Conditions
PreDiabetes, Overweight and Obesity
Interventions
Culturally Tailored Diabetes Prevention Program, Culturally Tailored DPP Enhanced with Socioeconomic Supports, Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Biospecimens for Identification of Diseases of the Pancreas.

NCT01392027
View directory record Official record
Conditions
Pancreatic Cancer, Chronic Pancreatitis, Type II Diabetes, Pancreatic Cysts, Healthy Control
Interventions
Blood Draw
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
712 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Jun 10, 2026, 5:43 PM EDT
Active, not recruiting Not applicable Interventional

The Inspiring Action to Prevent Diabetes Intervention

NCT06001801
View directory record Official record
Conditions
PreDiabetes
Interventions
Diabetes Prevention Program, INSPIRA
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Improving Health Habits in Impoverished Populations

NCT00569595
View directory record Official record
Conditions
Diabetes, Chronic Diseases
Interventions
Self-Care Stimulating Disease Prevention Program, Fighting Cancer with Advice
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2011 · Synced Jun 10, 2026, 5:43 PM EDT
Completed No phase listed Observational

Prevention of Amputation in Diabetic Foot Ulcers Using Amniotic Tissue

NCT02632929
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Not listed
Lead sponsor
Boise VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional Results available

Diabetes Prevention Program Feasibility Study of Breastfeeding

NCT04021602
View directory record Official record
Conditions
Pregnancy, Overweight and Obesity
Interventions
Diabetes Prevention Program, Breastfeeding Education, Usual Care
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Lakin, Kansas • Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional

Medicaid Incentives for the Prevention of Chronic Diseases: Diabetes Prevention

NCT03139019
View directory record Official record
Conditions
Diabetes Prevention
Interventions
Process incentives, Outcome incentives, Process and Outcome incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
596 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Health Diabetes Prevention Study

NCT05343494
View directory record Official record
Conditions
Gestational Diabetes, PreDiabetes, Hyperglycemia, Glucose Intolerance During Pregnancy
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Jun 10, 2026, 5:43 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

PASO A PASO: Tailored Diabetes Prevention Program for Spanish-Speaking Communities Feasibility Study

NCT07392008
View directory record Official record
Conditions
Pre Diabetic
Interventions
Paso a Paso
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional

Health Mindset as a Driver of Efficacy of a Diabetes Prevention Program in the Blackfeet Community

NCT04571723
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Diabetes Prevention Program, Health Mindset modified diabetes prevention program
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Browning, Montana
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional

MEDication Focused Outpatient Care for Underutilization of Secondary Prevention

NCT02215408
View directory record Official record
Conditions
Diabetes, Hyperlipidemia, Hypertension, Cardiovascular Disease
Interventions
CVRS Intervention
Behavioral
Lead sponsor
Korey Kennelty
Other
Eligibility
55 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
18
States / cities
Gainesville, Florida • Tampa, Florida • Pocatello, Idaho + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Jun 10, 2026, 5:43 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of Glucagon In the Prevention of Hypoglycemia During Mild Exercise

NCT03217175
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Bihormonal Bionic Pancreas, Insulin Only Bionic Pancreas, Glucagon, Placebo
Device · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Jun 10, 2026, 5:43 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

NCT05704309
View directory record Official record
Conditions
Diabetes, Alzheimer Disease, Dementia, Vascular, Dementia, PreDiabetes
Interventions
Not listed
Lead sponsor
Marinella Temprosa
Other
Eligibility
Not listed
Enrollment
1,976 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
27
States / cities
Phoenix, Arizona • Alhambra, California • San Diego, California + 21 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional

Taking Action Together- A Diabetes Prevention Program

NCT01039116
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
High Intensity, Low Intensity
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
9 Years to 11 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated May 3, 2011 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Body Healthy Souls in the Marshallese Population

NCT03377244
View directory record Official record
Conditions
Weight Loss, Pre Diabetes, Overweight and Obesity
Interventions
HBHS, HBHS Policy, WORD DPP
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional

A Family Based Intervention to Reduce the Risk of Type 2 Diabetes in Children

NCT01146314
View directory record Official record
Conditions
Pediatric Obesity, Type 2 Diabetes, Metabolic Syndrome
Interventions
Family Focused Lifestyle Intervention
Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
8 Years to 11 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional Results available

Latinos Combating Diabetes

NCT01831921
View directory record Official record
Conditions
Pre Diabetes, Obesity, Metabolic Syndrome
Interventions
Lifestyle Weight Loss, Counseling
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jun 10, 2026, 5:43 PM EDT
Completed No phase listed Observational

Improved Glycemic Control in Adult Subjects With Type 1 Diabetes on MDI Using Insulin Guidance Software

NCT00552734
View directory record Official record
Conditions
Diabetes
Interventions
Insulin Guidance Software
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 12, 2015 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Not applicable Interventional Results available

Exercise and the Receptor for Advanced Glycation End Products (RAGE)

NCT03534687
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Jun 10, 2026, 5:43 PM EDT
Completed Phase 1Phase 2 Interventional

Prevention of Autoimmune Destruction and Rejection of Human Pancreatic Islets Following Transplantation for Insulin Dependent Diabetes Mellitus

NCT00501709
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Belatacept and Raptiva
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Jun 10, 2026, 5:43 PM EDT