Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Nov 4, 2026, 8:46 AM EST

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Showing 217–240 of 620 matching trials from the live ClinicalTrials.gov search.
Conditions
Obesity, Insulin Resistance, Insulin Sensitivity, Prediabetes, Dyslipidemia, Diabetes
Interventions
Placebo-Control, Low-Dose Vitamin K2 (menaquinone-7; 45 mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
8 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Type 2, Coronary Disease
Interventions
Problem Solving Skills
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
Not listed
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Acute Kidney Injury
Interventions
Not listed
Lead sponsor
AstraZeneca
Industry
Eligibility
Not listed
Enrollment
539,310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Wilmington, Delaware • Washington D.C., District of Columbia
Conditions
Coronary Artery Disease, Cerebral Vascular Disease, Peripheral Artery Disease, Renal Insufficiency, Diabetes, COPD, Hypertension, Active Smoker, Cancer, CHF, Prior DVT/PE
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
New York, New York
Conditions
Diabetes Mellitus, Type 2, Food Supply, Poverty, Minority Health, Obesity
Interventions
Fresh organic vegetables
Dietary Supplement
Lead sponsor
Sansum Diabetes Research Institute
Other
Eligibility
18 Years and older
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Santa Barbara, California
Conditions
Type 1 Diabetes, Pregnancy, High Risk, Insulin Dependent Diabetes, Pregnancy Related
Interventions
Commercial AID system, Open source AID system
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Francisco, California
Conditions
Diabetes Mellitus, Type 2
Interventions
Financial support for healthy foods and free home delivery, Free home delivery
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,007 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Pasadena, California • Pleasanton, California
Terminated Not applicable Interventional

Cardiovascular Risk Clinic

NCT02136758
Conditions
Cardiovascular Disease, Coronary Artery Disease, Hypertension, Diabetes, Obesity
Interventions
CRC lifestyle modification program
Behavioral
Lead sponsor
Windber Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Windber, Pennsylvania
Conditions
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Interventions
Enrollment in existing SDRI diabetes education programs
Behavioral
Lead sponsor
Sansum Diabetes Research Institute
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Santa Barbara, California
Conditions
Overweight, Cardiovascular Diseases
Interventions
High carbohydrate and low glycemic index (GI) diet, Low carbohydrate and low GI diet, High carbohydrate and high GI diet, Low carbohydrate and high GI diet
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
30 Years and older
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
Baltimore, Maryland • Boston, Massachusetts
Completed Phase 1 Interventional Accepts healthy volunteers

Using Salsalate to Target Adipocyte Macrophage Infiltration

NCT02130804
Conditions
Diabetes Risk
Interventions
Salsalate (4 g/day), Placebo (4 g/day)
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Los Angeles, California
Completed Not applicable Interventional Results available

Evaluation of Group Lifestyle Balance Maintenance Strategies

NCT00869609
Conditions
Diabetes
Interventions
GLB Traditional Maintenance (TM), GLB-Carb-focused Maintenance (CF)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Diabetes Mellitus, Type 2, Preterm Birth, Pregnancy, High Risk, Diabetes, Gestational
Interventions
Sliding Scale Insulin, Up-Titration of Home Insulin, Continuous Insulin Infusion, Dexcom G6 Professional Continuous Glucose Monitor
Drug · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Up to 50 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Birmingham, Alabama • Portland, Oregon • Greenville, South Carolina + 1 more
Conditions
Breast Cancer, Bladder Cancer
Interventions
Not listed
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years and older
Enrollment
2,133,575 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
2
States / cities
Wilmington, Delaware • Washington D.C., District of Columbia
Conditions
Type 2 Diabetes, Depression, Obesity
Interventions
Learning 2 BREATHE, Colorado Blues
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Fort Collins, Colorado
Conditions
Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Type 2 Diabetes, PreDiabetes, Insulin Resistance
Interventions
Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Active Control
Behavioral · Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
Interventions
Intensive glycemic targets, Standard glycemic targets
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
828 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
5
States / cities
Birmingham, Alabama • Indianapolis, Indiana • Norman, Oklahoma + 2 more
Conditions
Diabetes Mellitus, Type 2
Interventions
Extension of Care
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
648 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
4
States / cities
Madison, Mississippi • Durham, North Carolina • Kannapolis, North Carolina + 1 more
Conditions
Type 2 Diabetes, Healthy (Controls)
Interventions
Not applicable- observational study
Other
Lead sponsor
Guardian Research Network, Inc.
Other
Eligibility
40 Years to 70 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Orangeburg, South Carolina • Walhalla, South Carolina
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluating Tools for Health Promotion and Disease Prevention

NCT00164658
Conditions
Coronary Heart Disease, Stroke, Diabetes, Breast Cancer, Ovarian Cancer, Colorectal Cancer
Interventions
Familial risk assessment and personalized prevention messages
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
35 Years to 65 Years
Enrollment
8,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
3
States / cities
Evanston, Illinois • Leawood, Kansas • Ann Arbor, Michigan
Completed Not applicable Interventional Results available

Sleep Extension or Regularity to Reduce Diabetes Risk

NCT06128265
Conditions
Overweight or Obesity
Interventions
Sleep Extension, Sleep Regularity
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Chicago, Illinois
Withdrawn Not applicable Interventional Accepts healthy volunteers

Behavioral Plant-Based Dietary Intervention in Latinos

NCT05444595
Conditions
Obesity, Metabolic Disease
Interventions
Behavioral plant-based dietary intervention, Standard care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Santa Barbara, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Active You: A Novel Exercise Program for African Americans

NCT04280783
Conditions
Cardiovascular Risk Factor, Prediabetes, Overweight and Obesity, Sedentary Behavior
Interventions
The Physical Activity for The Heart (PATH) intervention, Be Active Your Way Booklet
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Beaver Falls, Pennsylvania • Pittsburgh, Pennsylvania
Conditions
Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus
Interventions
Telehealth Bridge Visits, Standard of Care
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
20 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York