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ClinicalTrials.gov public records Last synced Oct 8, 2026, 10:15 PM EDT

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Showing 145–168 of 406 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Diabetic Foot Disease Clear all
Completed Not applicable Interventional

NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers

NCT02461641
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
NuShield, Affinity, Standard of Care
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
19 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
7
States / cities
Fresno, California • Indianapolis, Indiana • Opelousas, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Phase 2 Interventional

A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)

NCT01154374
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
MEBO Wound Ointment, Standard of Care (sterile saline moistened gauze)
Drug · Procedure
Lead sponsor
Skingenix, Inc.
Industry
Eligibility
18 Years to 79 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
New Haven, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Phase 3 Interventional Results available

Effectiveness of dermaPACE™ Device and Standard Treatment Compared to Standard Treatment Alone for Diabetic Foot Ulcers

NCT00536744
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
acoustical pulse energy (extracorporeal shockwave), Sham
Device · Other
Lead sponsor
SANUWAVE, Inc.
Industry
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
21
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 8, 2026, 10:15 PM EDT
Recruiting No phase listed Observational

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

NCT06104969
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetic Foot, Diabetes
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
9
States / cities
Tucson, Arizona • Los Angeles, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Phase 2 Interventional

Adipose Derived Regenerative Cellular Therapy of Chronic Wounds

NCT02092870
View directory record Official record
Conditions
Diabetic Foot, Venous Ulcer, Pressure Ulcer
Interventions
Adipose derived stem cells
Drug
Lead sponsor
Tower Outpatient Surgical Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Not applicable Interventional

APT001 Plasma/NO Generator to Treat Diabetic Foot Ulcer in Adults

NCT02356835
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
APT001, SHAM
Device
Lead sponsor
Origin Inc.
Industry
Eligibility
19 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
4
States / cities
Montgomery, Alabama • Fresno, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 8, 2026, 10:15 PM EDT
Terminated No phase listed Observational

Adjunct Collection of Additional Biorepository Data From Patients Enrolled in Diabetic Foot Consortium (DFC) Trials

NCT05092620
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Palo Alto, California • San Francisco, California • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 8, 2026, 10:15 PM EDT
Active, not recruiting Not applicable Interventional

Wearable Insoles for Recurrent Diabetic Ulcer Prevention

NCT07674420
View directory record Official record
Conditions
Diabetes, Peripheral Neuropathy, Diabetic Foot Ulcer
Interventions
Orpyx Sensory Insole System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 8, 2026, 10:15 PM EDT
Not listed Not applicable Interventional

Exploratory Study of the Efficacy of Standard of Care Revascularization of the Lower Extremity

NCT04720170
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Revascularization
Procedure
Lead sponsor
Diabetes and Glandular Disease Clinic
Industry
Eligibility
30 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2021 · Synced Oct 8, 2026, 10:15 PM EDT
Enrolling by invitation No phase listed Observational

Case Series of StimLabs Dehydrated Human Umbilical Cord Particulate for Acute and Chronic Wounds

NCT07414368
View directory record Official record
Conditions
Chronic Ulcers, Diabetic Foot Ulcers (DFU), DFU, Ulcer
Interventions
Corplex P is used to cover, protect, and provide a moist wound environment
Device
Lead sponsor
StimLabs
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 8, 2026, 10:15 PM EDT
Completed No phase listed Observational

The Effect of Implementing a Limb Loss Prevention Program on Amputation Rates

NCT03978715
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
No intervention-retrospective study
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Oct 8, 2026, 10:15 PM EDT
Recruiting Not applicable Interventional

Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC

NCT06515093
View directory record Official record
Conditions
Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
PelloGraft, SanoGraft
Other
Lead sponsor
Surgenex
Industry
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Vista, California • Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 8, 2026, 10:15 PM EDT
Terminated Not applicable Interventional

An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds

NCT05494450
View directory record Official record
Conditions
Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
ExufiberAG+
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
San Francisco, California • Miamisburg, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Transdermal Continuous Oxygen Therapy for Diabetic Foot Ulcers

NCT01291160
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Epiflo, Moist Wound Therapy
Device · Other
Lead sponsor
Neogenix, LLC dba Ogenix
Industry
Eligibility
20 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
14
States / cities
Phoenix, Arizona • Tucson, Arizona • Encinitas, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 13, 2014 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Phase 4 Interventional Results available

Using Santyl on Diabetic Foot Ulcers

NCT01408277
View directory record Official record
Conditions
Diabetic Foot Ulcers, Diabetic Foot Wounds
Interventions
Santyl, Control
Biological · Procedure
Lead sponsor
Healthpoint
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
7
States / cities
Phoenix, Arizona • Tucson, Arizona • Southfield, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2014 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Not applicable Interventional

Non-weight Bearing Exercise for Accelerated Healing of Diabetic Foot Ulcers

NCT05603273
View directory record Official record
Conditions
Type2diabetes, Foot Ulcer
Interventions
non-weight bearing exercise
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 8, 2026, 10:15 PM EDT
Terminated Phase 2 Interventional Results available

Efficacy and Safety of Intramuscular PDA-002 in Subjects With Diabetic Foot Ulcer With and Without PAD.

NCT02264288
View directory record Official record
Conditions
Peripheral Arterial Disease, Diabetic Foot
Interventions
PDA-002, Placebo
Biological · Other
Lead sponsor
Celularity Incorporated
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
45
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 8, 2026, 10:15 PM EDT
Completed No phase listed Observational

Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis (PCT)

NCT02308774
View directory record Official record
Conditions
Osteomyelitis
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 8, 2026, 10:15 PM EDT
Terminated Not applicable Interventional Results available

Diabetic Foot Infection Antibiotic Study

NCT01539811
View directory record Official record
Conditions
Diabetic Foot Infections
Interventions
Surgical incision and drainage of diabetic foot infection, Short course antibiotics, Long course antibiotics
Procedure · Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SkinTE™ in the Treatment of Diabetic Foot Wounds

NCT03881254
View directory record Official record
Conditions
Diabetic Foot, Diabetic Foot Ulcer, Ulcer Foot
Interventions
Human Autologous Homologous Skin Construct, Additional Outer Dressing Applicaiton, Offloading, Fibracol Wound Dressing
Other
Lead sponsor
PolarityTE
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Martinsville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Not applicable Interventional

Comparative Study of Two Application Regimens of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers

NCT01657474
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Weekly application of EpiFix plus standard of care, Biweekly application of EpiFix plus standard of care
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Roanoke, Virginia • Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 11, 2013 · Synced Oct 8, 2026, 10:15 PM EDT
Terminated Phase 3 Interventional

Efficacy and Safety Study in the Treatment of Chronic Diabetic Foot Ulcers

NCT00387101
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Dermal - Living Skin Replacement (Dermal - LSR)
Device
Lead sponsor
ApoPharma
Industry
Eligibility
18 Years to 84 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
12
States / cities
Tuscon, Arizona • Mather, California • San Diego, California + 8 more
Source: ClinicalTrials.gov public record
Updated May 2, 2008 · Synced Oct 8, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

How Shoes With Rocker Soles Affect Walking

NCT00006438
View directory record Official record
Conditions
Diabetic Feet
Interventions
Shoes with Rocker Soles
Device
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
40 Years to 60 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 1999
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 8, 2026, 10:15 PM EDT
Completed No phase listed Observational

Determination of the Pathophysicologic Collagen Changes in the Diabetic Achilles Tendon

NCT01382628
View directory record Official record
Conditions
Diabetic Foot Ulcers, Equinus Deformity
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 8, 2026, 10:15 PM EDT