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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 417 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Diabetic Ulcers Clear all

Conditions: Diabetic Foot, Foot Ulcer, Ulcer Foot, DFU, Foot Ulcer Due to Type 2 Diabetes Mellitus, Foot Ulcer Due to Type 1 Diabetes Mellitus, Diabetic Foot Ulcer
Interventions: XWRAP; Other
Lead sponsor: Applied Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Hollywood, Florida

Conditions: Diabetic Foot Ulcers
Interventions: EpiCord, Standard of Care; Biological · Other
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 13
States / cities: Birmingham, Alabama • Tucson, Arizona • Carlsbad, California + 10 more

Conditions: Diabetic Foot Ulcers, Diabetic Foot Wounds
Interventions: Collagenase Santyl Ointment, Placebo Comparator; Biological · Other
Lead sponsor: Healthpoint; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Diabetic Foot, Chronic Ulcer
Interventions: ActiGraft, Standard of Care; Device
Lead sponsor: RedDress Ltd.; Industry
Eligibility: 19 Years and older
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 12
States / cities: Montgomery, Alabama • Los Angeles, California • San Francisco, California + 8 more

Conditions: Diabetic Foot Ulcer, Lower Extremity Wound
Interventions: DermACELL AWM; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Fresno, California • Rocky Mount, North Carolina

Conditions: Foot Ulcer, Diabetic
Interventions: PriMatrix, Standard of Care; Device · Other
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 2
States / cities: Cumming, Georgia • Saginaw, Michigan

Conditions: Diabetic Foot Ulcers
Interventions: Gentamicin Topical Gel, Ciprofloxacin, Doxycycline; Drug
Lead sponsor: Royer Biomedical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 7
States / cities: Washington D.C., District of Columbia • Miami, Florida • Miami Lakes, Florida + 4 more

Conditions: Diabetic Foot Ulcer
Interventions: Standard of Care, PuraPly AM, PuraPly XT; Other · Device
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Clevland, Ohio

Conditions: Diabetic Foot Ulcers
Interventions: Tissue, Control; Other
Lead sponsor: Osiris Therapeutics; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 15
States / cities: Montgomery, Alabama • Glendale, Arizona • Encinitas, California + 12 more

Conditions: Diabetic Foot Ulcer, Diabetic Foot, Diabetes
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 9
States / cities: Tucson, Arizona • Los Angeles, California • San Francisco, California + 6 more

Conditions: Diabetic Neuropathy
Interventions: Neuropathy/Ulcer Homeopathic topical cream; Other
Lead sponsor: Calvary Hospital, Bronx, NY; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Diabetic Foot Ulcer, Diabetic Foot
Interventions: diabetic foot orthotic, Standard innersole; Device · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Type2diabetes, Foot Ulcer
Interventions: non-weight bearing exercise; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 75 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Diabete Mellitus, Foot Ulcer Chronic
Interventions: Placental Membrane; Biological
Lead sponsor: BioXTek; Industry
Eligibility: 45 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Phoenix, Arizona • Houston, Texas

Conditions: Foot Ulcer, Diabetic Foot
Interventions: Collagenase ointment, Modified Contact Cast System; Drug · Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 80 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Diabetic Ulcer
Interventions: AMD3100 injection + rhPDGF-BB topical; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 35 Years to 60 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetic Foot
Interventions: ON101 Cream, Aquacel® Hydrofiber® dressing; Drug · Other
Lead sponsor: Oneness Biotech Co., Ltd.; Industry
Eligibility: 20 Years to 80 Years
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: Fresno, California

Conditions: Diabetic Foot Ulcers, Venous Ulcers, Pressure Ulcers
Interventions: Autologous PRP Gel, Autologous PRP Injections, Autologous PRP Gel plus PRP Injections, Standard Wound Care; Device · Procedure
Lead sponsor: Arteriocyte, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 6
States / cities: Bakersfield, California • Idaho Falls, Idaho • Englewood, New Jersey + 3 more

Conditions: Diabetic Foot Ulcers
Interventions: Granexin gel, Vehicle gel; Drug · Other
Lead sponsor: Xequel Bio, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 6
States / cities: Los Angeles, California • Doral, Florida • Hialeah, Florida + 3 more

Conditions: Diabetic Foot Ulcer
Interventions: Restrata®, Wound Dressing; Device
Lead sponsor: Acera Surgical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Hoffman Estates, Illinois

Conditions: Diabetic Foot Ulcer
Interventions: Tissue Engineered Skin Substitute, Offloading, Amnionic Membrane Graft; Procedure · Device
Lead sponsor: Professional Education and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 3
States / cities: Martinsville, Virginia • Roanoke, Virginia

Conditions: Diabetic Foot Ulcer
Interventions: SECONDARY dressing gauze and tape, debridement, irrigation, Dermagraft, Oasis; Device · Procedure
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 85 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Diabetes, Diabetic Foot, Diabetic Foot Ulcer, Diabetic Wound
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 6
States / cities: San Francisco, California • Stanford, California • Miami, Florida + 3 more

Conditions: Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions: ExufiberAG+; Device
Lead sponsor: Molnlycke Health Care AB; Industry
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 2
States / cities: San Francisco, California • Miamisburg, Ohio

Search by objective public record fields.

A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers

Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers

Wound Edge Changes Following Treatment With Santyl

Safety and Efficacy of ActiGraft Pro Compared to Standard of Care in DFUs

DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers

A Study With Primatrix Dermal Repair Scaffold For The Treatment Of Diabetic Foot Ulcers

Safety and Efficacy of Gentamicin Topical Gel (AppliGel-G) for Treatment of Mild to Moderately Infected Diabetic Foot Ulcers

A Study to Evaluate the Efficacy of a Purified Native Type 1 Collagen Extracellular Matrix With Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers

Grafix® DFU: Open-Label Extension Option to Evaluate Safety & Efficacy of Grafix® for Chronic Diabetic Foot Ulcers

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

Effects of a Homeopathic Anti-inflammatory Topical Cream on Ulcers and Neuropathy in the Diabetic Foot

Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer

Non-weight Bearing Exercise for Accelerated Healing of Diabetic Foot Ulcers

Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing

EZCast-DFU Study With Portal for Application of Topical Medications

Endogenous Progenitors Cell Therapy for Diabetic Foot Ulcers

Evaluate the Efficacy and Safety of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers

Registry Trial of the Effectiveness of Platelet Rich Plasma for Chronic Non-Healing Wounds

A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer

Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers

Prospective, Comparitive, Randomized Study of Allograft Versus Skin Substitute in Non-healing Diabetic Foot Ulcers

VA MERIT: A Comparative Efficacy Study: Treatment of Non-Healing Diabetic

C-myc Biomarker Study for Diabetic Foot Ulcers

An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds