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Conditions: Peripheral Vascular Disease, Coronary Artery Disease, Peripheral Artery Disease, Arterial Occlusive Disease, Coronary Heart Disease
Interventions: Not listed
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,004 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 10
States / cities: Los Angeles, California • Ypsilanti, Michigan • Camden, New Jersey + 7 more

Conditions: Cancer, Psychological Distress, Adaptation, Psychological
Interventions: SHINE Psychosocial Intervention, Usual Supportive Care; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 10 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Thrombocytopenia Related to Chronic Liver Disease
Interventions: Avatrombopag, Placebo; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Influenza -Like Illness, Influenza A, Influenza Type B, Respiratory Viral Infection, Respiratory Tract Infections
Interventions: Not listed
Lead sponsor: Evidation Health; Industry
Eligibility: 18 Years and older
Enrollment: 5,233 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: San Mateo, California

Conditions: Pneumonia, Methicillin-Resistant Staphylococcus Aureus
Interventions: Polymerase Chain Reaction (PCR); Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Bronchiolitis
Interventions: Bronchiolitis quality improvement; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 1 Day to 2 Years
Enrollment: 1,321 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Radiology Information Systems
Interventions: Not listed
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 1 Year to 100 Years
Enrollment: 144,625 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2030
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Pneumocystis Infection, Infection, Pneumonia, Pneumocystis, Lung Disease, Fungal, Mycoses
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 3 Years to 99 Years
Enrollment: 1,015 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1999
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Pancreatic Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Colorectal Carcinoma, Unresectable Lung Non-Small Cell Carcinoma
Interventions: Biospecimen Collection, Computed Tomography, Electronic health record review, Medical Device Usage and Evaluation, Physical functions assessments, Positron Emission Tomography (PET), Survey Administration; Procedure · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Pleasanton, California

Conditions: Brain and Central Nervous System Tumors
Interventions: temozolomide, Imaging biomarker analysis, Photon Radiation Therapy; Drug · Other · Radiation
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Coronary Artery Disease
Interventions: Adenosine SPECT myocardial perfusion imaging, Combined adenosine / exercise SPECT myocardial perfusion imaging; Procedure
Lead sponsor: Midwest Heart Foundation; Other
Eligibility: 60 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 20
States / cities: Tucson, Arizona • Roseville, California • Sacramento, California + 16 more

Conditions: Sepsis, Septicemia, Sepsis Syndrome, Shock, Septic, Community Acquired Pneumonia
Interventions: Not listed
Lead sponsor: National Center for Genome Resources; Other
Eligibility: 6 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 3
States / cities: Detroit, Michigan • Durham, North Carolina

Conditions: Infertility
Interventions: Not listed
Lead sponsor: Progyny, Inc.; Industry
Eligibility: Up to 43 Years · Female only
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: Morristown, New Jersey • New York, New York

Conditions: Peripheral Pulmonary Lesions (PPLs)
Interventions: Rapid onsite evaluation; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 8
States / cities: Chicago, Illinois • Baltimore, Maryland • Burlington, Massachusetts + 4 more

Conditions: Retrospective Review
Interventions: Not listed
Lead sponsor: Miami Cardiac and Vascular Institute; Other
Eligibility: 35 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Fetal Conditions, Maternal; Procedure, Pregnancy Related, Twin to Twin Transfusion Syndrome, In Utero Procedure Affecting Fetus or Newborn, Chorion; Abnormal, Twin Reversal Arterial Perfusion Syndrome, Twin Monochorionic Monoamniotic Placenta, Chorioangioma, Vasa Previa
Interventions: Karl Storz Curved Scope, Karl Storz Straight Scope; Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Syphilis
Interventions: Rapid Point of Care (POC) Syphilis testing; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Breast Cancer
Interventions: high field strength magnetic resonance imaging, magnetic resonance spectroscopic imaging, chemical exchange saturation transfer magnetic resonance imaging, diffusion-weighted magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging; Procedure
Lead sponsor: Vanderbilt-Ingram Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: ENT Disorder, Nasal Procedures, Nasal Anesthesia, Nasal Mucosa Surgery
Interventions: Cocaine Hydrochloride Nasal Solution; Drug
Lead sponsor: Noden Pharma; Industry
Eligibility: 12 Years to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 4
States / cities: Columbia, South Carolina • Lugoff, South Carolina

Conditions: Cancer Diagnosis, Diagnostic Techniques and Procedures, Diagnostic Imaging
Interventions: F-18 FDG, Ga-68-DOTA-TATE, Positron Emission Tomography / Computed Tomography (PET/CT) Scan, Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Scan; Drug · Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Cancer
Interventions: Not listed
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: Not listed
Enrollment: 139,692 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2020
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Healthy, Pituitary Disease, Thyroid Disease
Interventions: TRH (Thyrotropin Releasing Hormone); Drug
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 2 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2014
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Device Convenience, Device Performance, Surgeons' Rating, Ergonomics
Interventions: Not listed
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Drug Reaction to Analgesic Nos
Interventions: RX0041 4%, Placebo, RX0041 8%; Drug
Lead sponsor: Pharmaceutical Project Solutions, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 648 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Mount Arlington, New Jersey • Columbia, South Carolina

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Angio-Seal Evolution Device Registry

Support and Healing Intervention for Adolescents With a Parent Diagnosed With Cancer (SHINE)

Once-Daily Oral Avatrombopag Tablets Used in Subjects With Chronic Liver Diseases and Thrombocytopenia Prior to Elective Surgical or Diagnostic Procedures

Home Testing of Respiratory Illness

Trial of MRSA Polymerase Chain Reaction for Pneumonia

Pediatric Bronchiolitis Quality Improvement

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Existing Radiologic Images

New Techniques for Using a Saline Wash as a Diagnostic Tool for Pneumocystis Pneumonia

Understanding New Cachexia Subtypes Through Observational Epidemiological Research

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

Both Exercise and Adenosine Stress Testing

Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests

Correlating Time-Lapse Parameters Detected by the Eeva™ System With Comprehensive Chromosome Screening Results

Advanced Robotic Techniques and Rapid Onsite Evaluation for Minimally Invasive Diagnosis and Next-Generation Sequencing.

Femoral Artery Crossover Rates in 1000 Consecutive Radial Cath Labs Procedures.

A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures

Offering Routine and Rapid Point of Care (POC) Syphilis Testing in Pregnant Patients Presenting to the Emergency Department

Ultra High Field MRI and MRS Techniques in Diagnosing Breast Cancer

Pharmacokinetics, Safety, and Tolerability Study of GOPRELTO® Nasal Solution and NUMBRINO™ Nasal Solution

Comparison of PET/CT vs. PET/MRI Using 2 Radiopharmaceuticals

Development of Computer-aided Detection and Diagnosis From Imaging Techniques

Study of Thyrotropin-Releasing Hormone in Normal Volunteers and in Patients With Thyroid or Pituitary Abnormalities

Use of Apple Vision Pro as Virtual Monitor for Diagnostic and Therapeutic Procedures

Topical Anesthetic for Procedures Through the Nose