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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Diaphragm Injury Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Emotional Freedom Technique and Diaphragmatic Breathing on Post Traumatic Stress Disorder (PTSD)

NCT00514956
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Emotional Freedom Techniques (EFT)
Behavioral
Lead sponsor
Soul Medicine Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
2
States / cities
Charleston, West Virginia • Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 21, 2009 · Synced Jun 25, 2026, 11:17 PM EDT
Recruiting Not applicable Interventional

GORE® ENFORM Biomaterial Product Study

NCT04718168
View directory record Official record
Conditions
Hernia, Ventral, Hernia, Hiatal, Hernia, Diaphragmatic, Incisional Hernia
Interventions
Gore ENFORM Biomaterial (Preperitoneal), Gore ENFORM Biomaterial (Intraperitoneal)
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
9
States / cities
San Diego, California • Denver, Colorado • Sarasota, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Jun 25, 2026, 11:17 PM EDT
Completed No phase listed Observational Results available

Diaphragm Pacing in Individuals With Spinal Cord Injuries

NCT04179799
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Diaphragm Pacing
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Jun 25, 2026, 11:17 PM EDT
Completed Not applicable Interventional Results available

Electrical Activation of The Diaphragm for Ventilatory Assist

NCT00010374
View directory record Official record
Conditions
Spinal Cord Injury, Quadriplegia
Interventions
NeuRx DPS
Device
Lead sponsor
Synapse Biomedical
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2008
U.S. locations
4
States / cities
Englewood, Colorado • Atlanta, Georgia • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Jun 25, 2026, 11:17 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Palliative Care Needs of Children With Rare Diseases and Their Families

NCT06938542
View directory record Official record
Conditions
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome, Early Infantile Epileptic Encephalopathy, FOXG1 Syndrome, KBG Syndrome, Noonan Syndrome, Severe Hemophilia A, Short Bowel Syndrome, Beta-Propeller Protein-Associated Neurodegeneration, Brain Injury of Prematurity With Periventricular Leukomalacia, Chromosome 17p13.3 Microdeletion Syndrome, Chromosome 1q43-1q44 Deletion, Cockayne Syndrome, Congenital Diaphragmatic Hernia, End-Stage Renal Disease With Cloacal Anomaly, Mitochondrial Depletion Disorder, Severe Factor VII Deficiency
Interventions
Family Centered pediatric palliative care for family caregivers of children with rare diseases.
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
12 Months to 99 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jun 25, 2026, 11:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using Ultrasound to Study Respiratory Muscle Function in Critically Ill Patients

NCT03139695
View directory record Official record
Conditions
Injury of Diaphragm, Mechanical Ventilation Complication, Critical Illness
Interventions
Ultrasound
Diagnostic Test
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Jun 25, 2026, 11:17 PM EDT
Recruiting Not applicable Interventional

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

NCT06538376
View directory record Official record
Conditions
Pulmonary Edema, Pneumonia, Atelectasis, Pleural Effusion, Acute Rejection of Lung Transplant (Disorder), Airway Obstruction, Rib Fractures, Acute Copd Exacerbation, Asthma COPD, Pulmonary Embolism, Hemothorax, Pneumothorax, Mesothelioma, Diaphragmatic Paralysis
Interventions
Portable Dynamic Digital Radiography (DDR)
Diagnostic Test
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Jun 25, 2026, 11:17 PM EDT
Completed No phase listed Observational

Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia

NCT01815554
View directory record Official record
Conditions
Tetraplegia, Spinal Cord Injury
Interventions
Not listed
Lead sponsor
Craig Hospital
Other
Eligibility
Not listed
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Jun 25, 2026, 11:17 PM EDT
Completed Not applicable Interventional

Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patients

NCT03440593
View directory record Official record
Conditions
Sepsis, Critical Illness, Respiratory Failure, Nutrition Disorders, Calorie Deficiency, Diaphragm Injury, Quadriceps Muscle Atrophy
Interventions
Caloric delivery will target results of IC measurement.
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Jun 25, 2026, 11:17 PM EDT
Completed No phase listed Observational

Hiatal Hernia and Pulmonary Involvement

NCT05716022
View directory record Official record
Conditions
Hiatal Hernia, Interstitial Lung Disease
Interventions
Blood Collection, Bronchoscopy
Diagnostic Test
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jun 25, 2026, 11:17 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury

NCT06101199
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation, SHAM Acute Intermittent Hypercapnic Hypoxia, SHAM Transcutaneous spinal cord stimulation
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Jun 25, 2026, 11:17 PM EDT
Completed No phase listed Observational

Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO

NCT00371241
View directory record Official record
Conditions
Persistent Fetal Circulation Syndrome, Diaphragmatic Hernia, Meconium Aspiration, Sepsis
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Day to 30 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Jun 25, 2026, 11:17 PM EDT
Recruiting Not applicable Interventional

The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

NCT05446272
View directory record Official record
Conditions
Extubation Failure, Bronchopulmonary Dysplasia, Death
Interventions
NIV-NAVA, NS-NIPPV
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
0 Days to 9 Weeks
Enrollment
478 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
17
States / cities
Little Rock, Arkansas • Loma Linda, California • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jun 25, 2026, 11:17 PM EDT
Completed No phase listed Observational

Diaphragm Pacing After Spinal Cord Injury

NCT02556125
View directory record Official record
Conditions
Injuries, Spinal Cord
Interventions
Diaphragm pacing
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Jun 25, 2026, 11:17 PM EDT
Recruiting Not applicable Interventional

Neurostimulation for Respiratory Function After Spinal Cord Injury

NCT05756894
View directory record Official record
Conditions
Spinal Cord Injuries, Cervical Spinal Cord Injury, Respiratory Function Impaired
Interventions
Neurostimulation, Repiratory training
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Jun 25, 2026, 11:17 PM EDT
Withdrawn No phase listed Observational

Re-Evaluation of Systemic Early Neuromuscular Blockade and Transthoracic Ultrasound Assessment of the Diaphragm

NCT03132896
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Diaphragm Injury, Neuromuscular Blockade
Interventions
Not listed
Lead sponsor
University Health Network, Toronto
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
6
States / cities
Boston, Massachusetts • Springfield, Massachusetts • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2019 · Synced Jun 25, 2026, 11:17 PM EDT
Completed Not applicable Interventional

Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants

NCT05968586
View directory record Official record
Conditions
Neonatal Oxygen Desaturation, Premature, Ventilator Lung; Newborn, Apnea of Prematurity
Interventions
Body positioning
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
1 Minute to 3 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Jun 25, 2026, 11:17 PM EDT
Recruiting No phase listed Observational

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

NCT04937868
View directory record Official record
Conditions
Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury, Hip Injuries, Liver Injury, Spleen Injury, Renal Injury, Diaphragm Injury, Aortic Rupture, Aortic Dissection, Bowel Disease, Vascular System Injuries, Sacral Fracture
Interventions
There are no interventions associated with this study
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
12,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Jun 25, 2026, 11:17 PM EDT
Completed Not applicable Interventional Results available

Effect of Diaphragm Stimulation During Surgery

NCT03303040
View directory record Official record
Conditions
Mechanical Ventilation Complication, Diaphragm Injury
Interventions
Electrical stimulation of hemidiaphragm
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Jun 25, 2026, 11:17 PM EDT
Terminated Phase 1 Interventional

Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)

NCT03526588
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia
Interventions
Autologous umbilical cord blood
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
10 Minutes to 7 Days
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Jun 25, 2026, 11:17 PM EDT
Recruiting Phase 2 Interventional

Janus Kinase Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction

NCT03681275
View directory record Official record
Conditions
Diaphragm Injury
Interventions
Tofacitinib 10 MG [Xeljanz], Placebo to match Tofacitinib
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced Jun 25, 2026, 11:17 PM EDT
Completed Not applicable Interventional

Orthostatic, Respiratory, Balance-Intervention

NCT04210063
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Inspiratory Muscle Training (IMT)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Jun 25, 2026, 11:17 PM EDT