- Conditions
- Dysfunctional Voiding, Urinary Dysfunction
- Interventions
- Diaphragmatic Breathing Exercises, Bladder Hygiene Education
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 59 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Raleigh, North Carolina
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Showing 1–24
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- Conditions
- Respiratory Muscles
- Interventions
- Carbon monoxide 200 ppm in air
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Post-Acute Sequelae of COVID-19
- Interventions
- Usual care of traditional treatment, Specific DB program/Diaphragmatic manipulation program
- Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Inadequate; Pulmonary Ventilation, Newborn, Infant, Very Low Birth Weight
- Interventions
- Nasal NIV-NAVA
- Device
- Lead sponsor
- Tarah T Colaizy
- Other
- Eligibility
- 7 Days to 1 Year
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa
- Conditions
- Sepsis
- Interventions
- Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
- Procedure · Drug · Device + 1 more
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Stress Disorders, Post-Traumatic
- Interventions
- Emotional Freedom Techniques (EFT)
- Behavioral
- Lead sponsor
- Soul Medicine Institute
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2009
- U.S. locations
- 2
- States / cities
- Charleston, West Virginia • Huntington, West Virginia
- Conditions
- Ventilator Induced Diaphragm Dysfunction
- Interventions
- TransAeris
- Device
- Lead sponsor
- Synapse Biomedical
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Spinal Cord Injuries
- Interventions
- Inspiratory Muscle Training (IMT)
- Other
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Acute Respiratory Distress Syndrome, Diaphragm Injury, Neuromuscular Blockade
- Interventions
- Not listed
- Lead sponsor
- University Health Network, Toronto
- Other
- Eligibility
- 19 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 6
- States / cities
- Boston, Massachusetts • Springfield, Massachusetts • Cleveland, Ohio + 3 more
- Conditions
- Congenital Diaphragmatic Hernia
- Interventions
- DING
- Procedure
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 1 Day to 1 Day
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Pompe Disease
- Interventions
- Diaphragm conditioning via phrenic nerve stimulation
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 2 Years to 65 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2023
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Congenital Diaphragmatic Hernia, Persistent Pulmonary Hypertension of the Newborn, Hypoxemic Respiratory Failure, Pulmonary Hypoplasia
- Interventions
- Milrinone, Placebo (5% Dextrose)
- Drug
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- 0 Hours to 168 Hours
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2025
- U.S. locations
- 19
- States / cities
- Birmingham, Alabama • Palo Alto, California • Atlanta, Georgia + 15 more
- Conditions
- Respiratory Function Loss, Respiratory Complication
- Interventions
- Fentanyl Injection
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Injuries, Spinal Cord
- Interventions
- Diaphragm pacing
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 2
- States / cities
- Gainesville, Florida • Jacksonville, Florida
- Conditions
- Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
- Interventions
- Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP), Diaphragm Ultrasound, Maximal Inspiratory Pressure
- Other · Diagnostic Test
- Lead sponsor
- Children's Hospital Los Angeles
- Other
- Eligibility
- 30 Days to 18 Years
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Tracheobronchomalacia
- Interventions
- Bethanechol
- Drug
- Lead sponsor
- Arkansas Children's Hospital Research Institute
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Rumination
- Interventions
- Diaphragmatic breathing, Muscle relaxation
- Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Dyspnea After Interscalene Nerve Block
- Interventions
- Maximum Inspiratory Pressure monitoring
- Diagnostic Test
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Mechanical Ventilation Complication
- Interventions
- Volume Support Mode Mechanical Ventilation, Assist Control Mode Mechanical Ventilation
- Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 468 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2027
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Iowa City, Iowa
- Conditions
- Hypertension, FXTAS
- Interventions
- HRV and respiratory coherence biofeedback
- Device
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Ventilator Induced Diaphragm Dysfunction
- Interventions
- Lungpacer Diaphragm Pacing Therapy
- Device
- Lead sponsor
- Lungpacer Medical Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 223 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 22
- States / cities
- Stanford, California • Aurora, Colorado • Gainesville, Florida + 17 more
- Conditions
- Dyspnea
- Interventions
- diaphragmatic breathing retraining, Health Promotion
- Behavioral
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2018
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Mechanical Ventilation
- Interventions
- Assist Control Mode and Pressure Support Mode Mechanical Ventilation
- Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- GERD
- Interventions
- Diaphragm Training
- Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida