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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Diet, High-Fat Clear all
Completed Not applicable Interventional

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness

NCT03935854
View directory record Official record
Conditions
Obesity, Ketogenic Dieting, Metabolic Syndrome, Bipolar Disorder, Schizophrenia, Weight Gain, Psychotropic Agents Causing Adverse Effects in Therapeutic Use, Brain Metabolic Disorder
Interventions
LCHF, Ketogenic Diet
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Jul 22, 2026, 2:00 PM EDT
Not listed Not applicable Interventional

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness

NCT05705063
View directory record Official record
Conditions
Bipolar Disorder I, Bipolar II Disorder, Bipolar I Disorder, Bipolar Disorder, Bipolar Depression, Bipolar and Related Disorders, Bipolar Disorder, Type 1, Bipolar Disorder, Type 2, Bipolar Disorder, Mixed, Obesity, Metabolic Syndrome, Ketogenic Dieting, Weight Gain, Brain Metabolic Disorder, Psychotropic Agents Causing Adverse Effects in Therapeutic Use
Interventions
LCHF Ketogenic Diet
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2023 · Synced Jul 22, 2026, 2:00 PM EDT
Not yet recruiting Not applicable Interventional

Effects of Whole Fruit on Blood Sugar in People With Type 2 Diabetes

NCT07376226
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Whole Fruit
Other
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 22, 2026, 2:00 PM EDT
Not listed Not applicable Interventional

Effect of Preoperative Diet on Perioperative Gut Microbiome

NCT05027763
View directory record Official record
Conditions
Surgical Site Infection
Interventions
high-fiber/low fat, fermented
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Jul 22, 2026, 2:00 PM EDT
Recruiting Not applicable Interventional

Cardiometabolic Effects of Pecan Snacking in Prediabetes

NCT07235358
View directory record Official record
Conditions
Prediabetes
Interventions
Pecan snacking, Usual diet
Behavioral · Other
Lead sponsor
Penn State University
Other
Eligibility
25 Years to 65 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Phase 4 Interventional

The Effect of Liraglutide on Dietary Lipid Induced Insulin Resistance in Humans

NCT02403284
View directory record Official record
Conditions
Insulin Resistance
Interventions
Liraglutide, Sugar Pill
Drug
Lead sponsor
Phoenix VA Health Care System
Federal
Eligibility
40 Years to 75 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 21, 2024 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

High Fat Diet: Oxidative and Cardiovascular Effects

NCT00696228
View directory record Official record
Conditions
Obesity
Interventions
Placebo, MUFA, PUFA, SFA
Dietary Supplement
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Effects on Insulin, Gut Peptides, and Appetite

NCT01891617
View directory record Official record
Conditions
Endocrine and Metabolic Responses to Exercise and Diets
Interventions
Exercise and diets
Other
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 65 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 12, 2016 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms of the Effect of Physical Activity on the Adaptation to a High-Fat Diet

NCT00611117
View directory record Official record
Conditions
Healthy
Interventions
Physical Activity Level
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 35 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Anti-inflammatory Effects of Fiber

NCT02781350
View directory record Official record
Conditions
Postprandial Inflammation
Interventions
HFHC meal, HFHC MEAL plus Fiber
Other · Dietary Supplement
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2016 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"ADAPT" The Adaptation to High Fat Diets Extention

NCT00493701
View directory record Official record
Conditions
Healthy
Interventions
High Fat Diet, Low Fat Diet
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 30 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Jul 22, 2026, 2:00 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Diet-Induced Changes in GEnetic Material

NCT06252922
View directory record Official record
Conditions
Diet, Healthy, Body Weight, Metabolic Disturbance
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 35 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Phase 2 Interventional

Low-Fat, High-Fiber Diet Compared to a Standard Diet in Treating Patients With Prostate Cancer

NCT00020995
View directory record Official record
Conditions
Prostate Cancer
Interventions
therapeutic dietary intervention
Procedure
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
40 Years to 80 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High Fat Diet on Muscle Metabolism

NCT02328235
View directory record Official record
Conditions
Diabetes
Interventions
High Saturated Fat Diet
Other
Lead sponsor
Kevin Davy
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib

NCT01002378
View directory record Official record
Conditions
Dietary Fats, Pharmacokinetics
Interventions
Regorafenib (Stivarga, BAY73-4506)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2013 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Carbohydrate vs. High Fat Diets in the Treatment of Obesity (JBR 0512)

NCT00123240
View directory record Official record
Conditions
Obesity
Interventions
Low calorie high carbohydrate diet, Low calorie high fat/protein diet
Behavioral
Lead sponsor
Rockefeller University
Other
Eligibility
30 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2012 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protective Effect of Exercise on Acute High-fat Overfeeding

NCT07633704
View directory record Official record
Conditions
Insulin Sensitivity/Resistance
Interventions
High Fat Overfeeding, High Fat Overfeeding + Exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
20 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a PUFA-rich Diet on Acute Metabolic and Inflammatory High-Fat Meal Responses

NCT02246933
View directory record Official record
Conditions
Inflammation, Obesity
Interventions
PUFA Diet, Control Diet
Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 35 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Jul 22, 2026, 2:00 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

High Fat Meal and Postprandial TG Levels With and Without Exercise Intervention

NCT05291767
View directory record Official record
Conditions
Ketogenic Diet, Exercise
Interventions
Diet, Exercise
Other · Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 45 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Jul 22, 2026, 2:00 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Food and Circadian Timing

NCT04743271
View directory record Official record
Conditions
Diet, High-Fat, Circadian Rhythm
Interventions
High-Fat Diet, Low-Fat Diet
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Mediterranean Full-Fat Dairy Study

NCT02781675
View directory record Official record
Conditions
Cardiovascular Disease, Dyslipidemia, Inflammation
Interventions
Dietary Intervention
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Jul 22, 2026, 2:00 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria

NCT05650112
View directory record Official record
Conditions
Healthy, Enteric Hyperoxaluria
Interventions
FB-001, Placebo
Biological
Lead sponsor
Federation Bio Inc.
Industry
Eligibility
18 Years to 74 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional

High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology

NCT04940468
View directory record Official record
Conditions
Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Acute, Lymphoma, Clostridium Difficile Infection
Interventions
Diet Intervention
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
9 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 22, 2026, 2:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Short Term Ketone Supplementation and Cardiometabolic Health

NCT04236388
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Ketone drink, Placebo drink
Dietary Supplement
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
50 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 22, 2026, 2:00 PM EDT