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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dietary Fat Metabolism Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

Effects of the Atkins Diet Versus a Low Fat Diet on Inflammation

NCT00993278
View directory record Official record
Conditions
Cardiovascular Health, Obesity
Interventions
Low-Carbohydrate (Modified Atkins) Diet, Low-Fat (Heart Healthy) Diet
Dietary Supplement
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2015 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of High Fruit, Vegetable, and Dairy Intake on Plasma Lipids and Blood Pressure in Healthy Individuals

NCT01404897
View directory record Official record
Conditions
Cardiovascular Disease, Dyslipidemia, Blood Pressure
Interventions
Dietary Intervention
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
22 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2015 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Effect of Changing Diet on Fasting and Post Fat Load Lipoproteins

NCT00593424
View directory record Official record
Conditions
Hypertriglyceridemia, Diabetes Mellitus
Interventions
Low Fat/High Carbohydrate, High Monounsaturated Fat/Low Carbohydrate
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2011 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a High Protein, High Fiber Dietary Supplement on Weight and Fat Loss

NCT03057873
View directory record Official record
Conditions
Overweight
Interventions
High protein, high fiber dietary supplement, Placebo
Dietary Supplement
Lead sponsor
Beachbody
Industry
Eligibility
25 Years to 50 Years
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Phase 1 Interventional

Effect of High Monounsaturated Fat Diet on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes

NCT00622960
View directory record Official record
Conditions
Overweight, Obesity, Type 2 Diabetes
Interventions
High-MUFA diet, High-CHO diet
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
30 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2008 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism

NCT03878108
View directory record Official record
Conditions
Healthy, Healthy Volunteers
Interventions
LCHF diet, LFHC diet
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Jul 23, 2026, 10:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pilot Study to Test Dietary Fat Delivery

NCT02101996
View directory record Official record
Conditions
Insulin Resistance
Interventions
high-fat diet
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
30 Years to 50 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced Jul 23, 2026, 10:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease

NCT02075710
View directory record Official record
Conditions
Overweight and Obesity
Interventions
High sugar/meal feed, High sugar/nibble, High fat/meal feed, High fat/nibble, High sugar/ 3 meals a day, High fat/ 3 meals a day
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
20 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Jul 23, 2026, 10:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

NCT05165706
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Insulin Resistance, Obesity, Nonalcoholic Steatohepatitis, Nonalcoholic Fatty Liver, Diet Modification
Interventions
Dietary Intervention Mediterranean Low Carbohydrate Diet, Dietary Intervention Standard Low Carbohydrate Diet, Dietary Intervention Standard Low Fat Diet
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
35 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Critical Periods of Exercise

NCT01041820
View directory record Official record
Conditions
Metabolism
Interventions
Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
3 Years to 7 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 24, 2019 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation

NCT00123214
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Controlled Dietary Intervention
Drug
Lead sponsor
St. Vincent's Medical Center
Other
Eligibility
25 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2006 · Synced Jul 23, 2026, 10:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dietary Supplementation on Body Fat Composition

NCT06296251
View directory record Official record
Conditions
Dyslipidemias, Pre-diabetes
Interventions
Placebo treatment, Plant derived phenolics
Other · Dietary Supplement
Lead sponsor
Brightseed
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Phase 2Phase 3 Interventional

Low Glycemic Load Diets in Latino Children at Risk for Type 2 Diabetes

NCT01068197
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus
Interventions
Low Glycemic Load Diet versus Low Fat Diet
Behavioral
Lead sponsor
Nazrat Mirza
Other
Eligibility
7 Years to 14 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2014 · Synced Jul 23, 2026, 10:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Dietary Reversal of the Reprometabolic Syndrome

NCT07227766
View directory record Official record
Conditions
Obesity & Overweight, Infertility, Female
Interventions
Low-fat diet
Dietary Supplement
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Phase 1Phase 2 Interventional

Efficacy of Increasing Physical Activity to Reduce Children's Visceral Fat

NCT00359957
View directory record Official record
Conditions
Obesity
Interventions
Pediatric Obesity Intervention (STANDARD), Pediatric Obesity Intervention + High Activity (ADDED)
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 12 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 1, 2010 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Class of Dietary Fat Affect Insulin Resistance?

NCT01541592
View directory record Official record
Conditions
Insulin Resistance
Interventions
Dietary fat
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2014 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet and Activity Promotion Among Older Working Adults

NCT01233063
View directory record Official record
Conditions
Cardiovascular Disease, Diabetes, Obesity, Aging
Interventions
Physical Activity and Diet Intervention via Alive2
Behavioral
Lead sponsor
Berkeley Analytics, Inc.
Industry
Eligibility
50 Years and older
Enrollment
610 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nudging Nutrition With Monetary Incentives Environmental Cues

NCT02461108
View directory record Official record
Conditions
Obesity, Food Labeling, Health Behavior, Diet
Interventions
Subsidy, Tax, Tax and subsidy
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional

The Effect of a Low-fat Vegan Dietary Intervention on Intracellular Lipid, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes

NCT06106035
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2 in Obese
Interventions
low-fat vegan diet
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Jul 23, 2026, 10:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

NCT00072917
View directory record Official record
Conditions
Obesity, Thinness, Weight Gain
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
25 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 17, 2010 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Effect of High Fat and High Glycemic Diets

NCT01494935
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
High Glycemic Diet, Control diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 23, 2026, 10:41 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Effect of Oral Alpha-Cyclodextrin on Fecal Fat Excretion

NCT01910558
View directory record Official record
Conditions
Obesity, Cardiovascular Disease
Interventions
Alpha-cyclodextrin and digestible starch, Alpha-cyclodextrin, Digestible starch
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 26, 2016 · Synced Jul 23, 2026, 10:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fast Food Study: Assessment of the Effects of Fast-Food on Inflammatory Markers

NCT00233311
View directory record Official record
Conditions
Heart Diseases, Diabetes, Obesity
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 5, 2012 · Synced Jul 23, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake

NCT01399632
View directory record Official record
Conditions
Overweight, Cardiovascular Diseases
Interventions
Low Fat and High Carbohydrate Diet, High Fat and Low Carbohydrate Diet
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 5, 2016 · Synced Jul 23, 2026, 10:41 PM EDT