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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Stroke, Ischemic Stroke, Cerebrovascular Accident
Interventions
Beet it Beetroot juice, Beet It Placebo Beetroot juice
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate Supplementation and Muscle Blood Flow

NCT03459027
Conditions
Vasodilation, Blood Pressure, Active Hyperemia, Aging
Interventions
Super Beets, Beetroot powder
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
60 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Dietary Nitrate for Heart Failure

NCT01682356
Conditions
Heart Failure, Hypertension, Pulmonary
Interventions
Beetroot juice
Dietary Supplement
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
2
States / cities
Indianapolis, Indiana • St Louis, Missouri
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Beetroot Juice on Blood Pressure Regulation in Post Menopausal Women

NCT03380000
Conditions
Postmenopausal Women
Interventions
Beetroot juice, Beetroot juice placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 80 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Stroke, CVA
Interventions
Beetroot Juice supplement, Placebo supplement
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 89 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy Long-term Dietary Nitrate Consumption to Plasma Nitrite Conversion

NCT05380167
Conditions
Cardiovascular Diseases in Old Age
Interventions
BRJ Nitrate, BRJ Placebo
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
40 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate and Vitamin C on Vascular Health Oxidative Stress

NCT04283630
Conditions
Endothelial Dysfunction
Interventions
Dietary nitrate in the form of beetroot juice for all participnats, Nature Made vitamin c 1000 mg, Placebo
Dietary Supplement
Lead sponsor
David Travis Thomas
Other
Eligibility
50 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Lexington, Kentucky
Conditions
Peripheral Arterial Disease, Walking, Difficulty, Inflammation
Interventions
Calf Plantar flexion, Dietary nitrate
Device · Dietary Supplement
Lead sponsor
University of Wisconsin, La Crosse
Other
Eligibility
40 Years to 90 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
La Crosse, Wisconsin
Conditions
Aging
Interventions
Beetroot Juice, Placebo Beetroot Juice
Dietary Supplement · Other
Lead sponsor
Marquette University
Other
Eligibility
60 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Mitochondrial Energetics, Dietary Nitrate, Disuse Atrophy (Muscle) of Lower Leg
Interventions
Beetroot Juice - Active, Placebo Beetroot Juice Without Nitrate
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Results available

Dietary Nitrate Supplementation and Thermoregulation

NCT03506646
Conditions
Peripheral Arterial Disease, Peripheral Artery Disease
Interventions
Placebo, Beet root juice
Dietary Supplement
Lead sponsor
University of Nebraska
Other
Eligibility
50 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Nitrate and Physiological Aging

NCT02593305
Conditions
Aging
Interventions
Super Beets, Super Beets Placebo
Dietary Supplement
Lead sponsor
Darren P Casey
Other
Eligibility
18 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Peripheral Arterial Disease, Type II Diabetes Mellitus
Interventions
Beetroot Juice (Beet-It Stamina Shot) and Exercise Training, Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
50 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Peripheral Arterial Disease
Interventions
Beetroot juice, Beetroot juice placebo
Drug
Lead sponsor
David N. Proctor, PhD
Other
Eligibility
21 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Peripheral Artery Disease
Interventions
Sodium Nitrate, Placebo
Dietary Supplement · Other
Lead sponsor
University of Iowa
Other
Eligibility
50 Years to 85 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate and Exercise Performance in Middle to Older Aged Adults

NCT03371966
Conditions
Aging
Interventions
High Nitrate Beetroot Juice, Low Nitrate Beetroot Juice
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
40 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Secondary Amenorrhea
Interventions
Beetroot Juice - Active, Placebo Beetroot Juice Without Nitrate
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Coronary Arteriosclerosis
Interventions
Forearm blood flow study, Brachial artery reactivity study, Treadmill exercise test
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
22 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Healthy
Interventions
concentrated beet root juice, Placebo beet root juice
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 34 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study

NCT03617302
Conditions
Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension, Cognitive Decline
Interventions
Experimental: Nitrate-containing, Placebo: Nitrate-depleted
Drug
Lead sponsor
Gary L. Pierce, PhD
Other
Eligibility
50 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Beet Juice and Diet in Female Rowers

NCT06045845
Conditions
Dietary Habits, Nitrates, Exercise
Interventions
Beet Juice, Placebo
Dietary Supplement
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Lawrence, Kansas
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals

NCT03595774
Conditions
Aging, Sarcopenia
Interventions
Beet root juice
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
65 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Hypertension, Elevated Blood Pressure
Interventions
Vascanox® HP
Dietary Supplement
Lead sponsor
Calroy Health Sciences
Industry
Eligibility
25 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Nashville, Tennessee