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ClinicalTrials.gov public records Last synced Oct 22, 2026, 11:30 AM EDT

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Showing 625–648 of 14,927 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Digestive Disorders Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

Challenge Study of an ETEC Vaccine

NCT01922856
View directory record Official record
Conditions
Enteritis; Escherichia Coli, Enterotoxigenic
Interventions
LTR192G with dscCfaE, No Intervention
Biological · Other
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Baltimore, Maryland • Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 6, 2017 · Synced Oct 22, 2026, 11:30 AM EDT
Terminated Not applicable Interventional Results available

Educational-Medical-Behavioral Treatment of Fecal Incontinence

NCT01717456
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Education, Fiber supplements, Laxatives or anti-diarrheals, Pelvic floor muscle exercises, Tips on how to prevent fecal incontinence, Daily diary, Protective pads or garments
Other · Dietary Supplement · Drug + 1 more
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2017 · Synced Oct 22, 2026, 11:30 AM EDT
Terminated Phase 1 Interventional Results available

An Open-Label Study of Ruxolitinib Given With Chemotherapy in Patients With Advanced Solid Tumors

NCT01822756
View directory record Official record
Conditions
Solid Tumors, Pancreatic Cancer
Interventions
ruxolitinib, gemcitabine, nab-paclitaxel, filgrastim
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
5
States / cities
Birmingham, Alabama • Gainesville, Florida • Sarasota, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Oct 22, 2026, 11:30 AM EDT
Terminated Phase 2 Interventional Results available

Effectiveness and Safety Study of TACE Plus Oral Sorafenib for Unresectable HCC

NCT00576056
View directory record Official record
Conditions
Carcinoma, Hepatocellular
Interventions
Sorafenib, TACE
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Oct 22, 2026, 11:30 AM EDT
Terminated No phase listed Observational

Effect of Serotonin Level on Constipation Caused by Chemotherapy in Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT00536523
View directory record Official record
Conditions
Constipation, Bowel Obstruction, Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2014 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Phase 1 Interventional

An Investigation of Oral BT051 in Subjects With Moderately to Severely Active Ulcerative Colitis (UC)

NCT05084261
View directory record Official record
Conditions
Ulcerative Colitis
Interventions
BT051 200 mg, BT051 800 mg, BT051 3200 mg, Matching Placebo
Drug
Lead sponsor
Adiso Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Rialto, California • Kissimmee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Oct 22, 2026, 11:30 AM EDT
Recruiting Not applicable Interventional

Transventricular Off-pump Mitral Valve Repair

NCT07726173
View directory record Official record
Conditions
Mitral Valve (MV) Regurgitation
Interventions
TRANSOM
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis

NCT02372383
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Ethambutol, Rifampin, Azithromycin, Pancrelipase
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
16 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Oct 22, 2026, 11:30 AM EDT
Terminated Phase 1 Interventional

Proton Beam Therapy to Treat Esophageal Cancer

NCT02023541
View directory record Official record
Conditions
Esophageal Squamous Cell Carcinoma, Adenocarcinoma Of Esophagus
Interventions
Proton beam therapy
Radiation
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 22, 2026, 11:30 AM EDT
Completed No phase listed Observational

Per-Oral Endoscopic Myotomy

NCT01402518
View directory record Official record
Conditions
Achalasia
Interventions
Per-oral enodscopic myotomy
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Endoscopic Ultrasound (EUS)-Guided Ablation of Pancreatic Cysts

NCT01643460
View directory record Official record
Conditions
Pancreatic Cyst, Pancreatic Intraductal Papillary-Mucinous Neoplasm, Cystadenoma, Mucinous, Papillary Mucinous Cystadenoma, Borderline Malignancy
Interventions
98% Ethanol & Paclitaxel injection
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Infant Study of Inhaled Saline in Cystic Fibrosis

NCT00709280
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
7% Hypertonic Saline (HS), 0.9% Isotonic Saline (IS)
Drug
Lead sponsor
CF Therapeutics Development Network Coordinating Center
Network
Eligibility
4 Months to 59 Months
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
28
States / cities
Birmingham, Alabama • Phoenix, Arizona • Palo Alto, California + 24 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2013 · Synced Oct 22, 2026, 11:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Preventive Health Behavior in Women

NCT00723996
View directory record Official record
Conditions
Colon Cancer
Interventions
Behavioral Study in Women
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 75 Years · Female only
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 16, 2016 · Synced Oct 22, 2026, 11:30 AM EDT
Terminated Phase 4 Interventional

Study of CryoSpray Ablation of Low Grade or High Grade Dysplasia Within Barrett's Esophagus

NCT00526786
View directory record Official record
Conditions
Barrett's Esophagus, High Grade Dysplasia, Low Grade Dysplasia
Interventions
CryoSpray Ablation System (510(k) NO: K070893)
Device
Lead sponsor
CSA Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
16
States / cities
Orange, California • Norwalk, Connecticut • Tampa, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2014 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetic Study on G1090N (Nitazoxanide) Capsules in Healthy Volunteers

NCT07110441
View directory record Official record
Conditions
Acute-on-Chronic Liver Failure
Interventions
Single Dose G1090N, Multiple dosing of G1090N
Drug
Lead sponsor
Genfit
Industry
Eligibility
18 Years to 55 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Phase 3 Interventional

Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors

NCT03781154
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Group Exercise
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
4
States / cities
Aurora, Colorado • Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 22, 2026, 11:30 AM EDT
Active, not recruiting No phase listed Observational

Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence

NCT03283540
View directory record Official record
Conditions
Rectal Cancer
Interventions
TaTME, TME
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Phase 2 Interventional Results available

Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix

NCT01580410
View directory record Official record
Conditions
Carcinoma of the Appendix, Primary Peritoneal Cavity Cancer
Interventions
mitomycin C, oxaliplatin, therapeutic conventional surgery, quality-of-life assessment, hyperthermic intraperitoneal chemotherapy
Drug · Procedure · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
3
States / cities
Winston-Salem, North Carolina • Pittsburgh, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 3, 2018 · Synced Oct 22, 2026, 11:30 AM EDT
Active, not recruiting Not applicable Interventional

Monopolar Current Cutting Knife vs Bipolar RFA Knife

NCT04919824
View directory record Official record
Conditions
Gastrointestinal Neoplasms
Interventions
Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 22, 2026, 11:30 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Pilot Study of Pancreatic Cancer Screening

NCT05058846
View directory record Official record
Conditions
Pancreatic Carcinoma
Interventions
Biospecimen Collection, Magnetic Resonance Cholangiopancreatography, Magnetic Resonance Imaging, Endoscopic ultrasound, Questionnaires
Procedure · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 22, 2026, 11:30 AM EDT
Recruiting No phase listed Observational

Abbott Cephea Mitral Valve Disease Registry

NCT07069673
View directory record Official record
Conditions
Mitral Regurgitation, Mitral Stenosis, Mitral Valve Disease, Mitral Valve (MV) Regurgitation, Mitral Annulus Calcification, Mitral Valve Replacement, Transcatheter Valve Replacement
Interventions
Not listed
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
24
States / cities
Birmingham, Alabama • Phoenix, Arizona • Thousand Oaks, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Not applicable Interventional

Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis

NCT03070210
View directory record Official record
Conditions
Pancreatitis, Chronic, Abdominal Pain
Interventions
EUS-celiac ganglia block (EUS-CGB), EUS-celiac plexus block (EUS-CPB)
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2020 · Synced Oct 22, 2026, 11:30 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)

NCT01239082
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Colonoscopy, Fecal immunochemical test (FIT)
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 75 Years
Enrollment
50,126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2028
U.S. locations
45
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Fresno, California + 42 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 22, 2026, 11:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing Engagement With Messages Regarding CRC Screening Among Adults Aged 45-49

NCT05281159
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Neoplasms
Interventions
Risk Information, Risk Information + Action
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
45 Years to 49 Years
Enrollment
20,509 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Westwood, Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 22, 2026, 11:30 AM EDT