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Showing 1–24 of 237 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Digital Health Intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Small Moments Big Impact (SMBI)

NCT03887832
View directory record Official record
Conditions
Empathy
Interventions
SMBI digital app, media package, standard newborn and infant care
Other · Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Results available

Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

NCT04367506
View directory record Official record
Conditions
Tobacco Cessation
Interventions
BecomeAnEX, Usual Care
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional

A Megastudy of Single-Session Interventions for Depression

NCT06856668
View directory record Official record
Conditions
Depression - Major Depressive Disorder
Interventions
Behavioral Activation (Action Brings Change Project 10-Minute Version), Mindful Acceptance, Moral Elevation, Mindful Attention Skills, 5 Habits to Beat Depression, Interactive Cognitive Reappraisal, Expressive Writing (AI-supported), Inner Child Healing Walk, Savoring Strategies, Personalized Intervention Recommender, Dialectical Behavioral Therapy Skills, All about Trout, Reframing Negative Thoughts
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
7,505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Charge: A Text Messaging-based Weight Loss Intervention

NCT03254940
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Charge
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
534 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Jul 21, 2026, 10:08 PM EDT
Active, not recruiting Not applicable Interventional

Improving Care, Accelerating Recovery and Education

NCT06233747
View directory record Official record
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Increasing Digital Equity and Access Among Rural Patients (IDEA) Study

NCT05209451
View directory record Official record
Conditions
Smoking Cessation
Interventions
Digital, evidence-based behavioral health program for smoking cessation, Bluetooth enabled iPad, Coaching Support
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digital Narrative Bibliotherapy as a Scalable Intervention for Suicidal Thoughts

NCT05351645
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Treatment
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Jul 21, 2026, 10:08 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

mPATH-Cloud for Colorectal Cancer Screening

NCT06441487
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Mobile Health Decision Support, Usual care
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
45 Years to 73 Years
Enrollment
1,062 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional

Achieving Chronic Care equiTy by leVeraging the Telehealth Ecosystem

NCT06598436
View directory record Official record
Conditions
Diabetes
Interventions
Digital Health Coaching (Patient-Level Intervention), Practice Facilitation (Clinic-Level Intervention)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

NCT07477184
View directory record Official record
Conditions
Sleep Health, Stress, Anxiety, Physical Activity, Nutrition, Cognition
Interventions
Sleep enhancement intervention, Standard of Care (Investigator Choice)
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimal Digital Weight Loss Treatment for Rural Individuals

NCT06105957
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Core, Facilitated Weekly Group Sessions, Counselor Crafted Feedback, Individual Coaching Calls, Pre-Scripted Feedback
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
616 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digital Intervention to Promote Medical Trainee Well-being (OptimalWork Pilot)

NCT06914843
View directory record Official record
Conditions
Mental Health Wellness 1
Interventions
OptimalWork, Podcast Listening
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional

DMHI for At-Risk College Students

NCT06608498
View directory record Official record
Conditions
Prodromal Symptoms, Psychosis
Interventions
SPARK Coping
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jul 21, 2026, 10:08 PM EDT
Not yet recruiting Not applicable Interventional

Reset: Enhancing Weight Loss in a Digital Intervention

NCT07032571
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions
Core Behavioral Weight Loss Intervention, Limit Red Zone Foods, Limit Eating Window, Increase Protein, Increase Fiber Intake
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Youth-Led Intervention to Improve Blood Pressure

NCT05029687
View directory record Official record
Conditions
Hypertension, Adolescent Behavior, Health Knowledge, Attitudes, Practice
Interventions
Youth-Led Hypertension Education Digital Intervention
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
14 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Outcomes of a Self-guided Versus Therapist-guided Online Mental Health Treatment

NCT04810988
View directory record Official record
Conditions
Depression, Anxiety, Mood
Interventions
Unified Protocol, Therapist Support
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2024 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Move Together Boston Feasibility Pilot (Sit Less, Move More App for Black Breast Cancer Survivors & At-Risk Relatives)

NCT05011279
View directory record Official record
Conditions
Breast Cancer Survivor, Breast Cancer, Fitness Trackers
Interventions
Move Together app/Garmin Activity Tracker
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
3
States / cities
Boston, Massachusetts • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional

PATH to Health: An Exploration of Digital Behavioral Weight Loss Approaches

NCT05929469
View directory record Official record
Conditions
Overweight, Obesity, Overweight and Obesity
Interventions
App, Fully Automated Kick-Off, Human-Enhanced Kick-Off, Check-In, Counseling
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Jul 21, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents

NCT06959901
View directory record Official record
Conditions
Obesity and Diabetes Mellitus, Type 2, Diabetes Prevention
Interventions
PATHS-UP Mobile Phone Application
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Digital Mental Health and Wellness Intervention for Adults: A Randomized Control Trial of COMET

NCT04586192
View directory record Official record
Conditions
Depressive Symptoms, Anxiety
Interventions
Common Elements Toolbox- Adult version (COMET-A), Self-awareness Control
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 3, 2021 · Synced Jul 21, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Trial in HPV Prevention for the U.S. Vietnamese Community

NCT07637630
View directory record Official record
Conditions
HPV-related Cancers, HPV Vaccination
Interventions
Expert Video, Self-persuasion, Narrative Storytelling, Motivational Interviewing, Constant Component
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implementing a Digitally-enabled Community Health Worker Intervention for Patients With Heart Failure

NCT05130008
View directory record Official record
Conditions
Heart Failure，Congestive
Interventions
Digitally-enabled CHW Care, Usual CHW Care
Other · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2025 · Synced Jul 21, 2026, 10:08 PM EDT
Not listed Phase 4 Interventional

Digital Health Feedback System for Longitudinal Measurement of Medication Adherence During Anti-Retroviral (ARV)Therapy

NCT02800655
View directory record Official record
Conditions
HIV
Interventions
Digital Health Feedback System
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Jul 21, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Evaluation of Digital Peer-Support Intervention for College Students

NCT07460635
View directory record Official record
Conditions
Peer Support Interventions, Mental Health
Interventions
Be There Certificate
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 21, 2026, 10:08 PM EDT