Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 4:25 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 1,131 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Disability Diagnosis Clear all

Conditions: Behavioral Manifestations of Lesch-Nyhan Disease
Interventions: sapropterin; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 4 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Low Back Pain
Interventions: ED Physical Therapy; Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Post-Traumatic Stress Disorder, Chronic Low Back Pain, Chronic Neck Pain
Interventions: Yoga and Mantram Repetition, Veteran Calm; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Chromosome 13 Aneuploidy, Chromosome 18 Aneuploidy, Chromosome 21 Aneuploidy, Sex Chromosome Aberrations, Other Microdeletions
Interventions: Blood draw, Cheek swab/Saliva Sampling; Procedure
Lead sponsor: Natera, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,781 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Down Syndrome, Obstructive Sleep Apnea
Interventions: Open-ended semi-structured interviews; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 6 Years to 17 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: X-linked Adrenoleukodystrophy
Interventions: exercise training; Behavioral
Lead sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.; Other
Eligibility: 21 Years to 70 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Osteoarthritis
Interventions: Not listed
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 50 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Fragile X Syndrome
Interventions: SPG601, Placebo; Drug
Lead sponsor: Spinogenix; Industry
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Down Syndrome, Obstructive Sleep Apnea Syndrome
Interventions: Continuous positive airway pressure, Sham or placebo continuous positive airway pressure; Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 8 Years to 20 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
Interventions: Not listed
Lead sponsor: Natera, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 4
States / cities: Boston, Massachusetts • Glen Cove, New York • New York, New York + 1 more

Conditions: Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem, Development Delay
Interventions: Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 24 Months to 57 Months
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Cos Cob, Connecticut

Conditions: Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
Interventions: Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 5 Years to 17 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Down Syndrome, Gross Motor Delay, Cerebral Palsy
Interventions: Permobil Explorer Mini, Portable Mobility Aid for Children (PUMA); Device
Lead sponsor: University of Washington; Other
Eligibility: 12 Months to 60 Months
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Down Syndrome, Down Syndrome (Trisomy 21)
Interventions: Mindfulness-Based Therapy for Insomnia, Wait-list control; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 12 Months to 30 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Sleep Disorders
Interventions: Circadin 2/5/10 mg, Placebo; Drug
Lead sponsor: Neurim Pharmaceuticals Ltd.; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 18
States / cities: Phoenix, Arizona • Miami Lakes, Florida • Orange City, Florida + 14 more

Conditions: Rett Syndrome
Interventions: None interventional; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 99 Years
Enrollment: 20 participants
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Prader Willi Syndrome, Obsessive-compulsive Disorder
Interventions: Cognitive-behavioral therapy, Wait-list control; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 6 Years to 17 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Hypothyroidism, Trisomy 21
Interventions: Liquid stable levothyroxine (L-T4) Tirosint-SOL, Oral tablet levothyroxine (L-T4); Drug
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 2 Months to 4 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Fragile X Syndrome (FXS)
Interventions: 18F-FTC-146; Drug
Lead sponsor: Guido A. Davidzon, MD, SM; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Stanford, California

Conditions: Down Syndrome
Interventions: No Intervention; Other
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 6 Years to 11 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 3
States / cities: Tucson, Arizona • Boston, Massachusetts • Durham, North Carolina

Conditions: Intellectual Disability, Developmental Disability
Interventions: VCU-RRTC Online Course, Zoom Technical Assistance Sessions (6 total); Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Ischemic Stroke, Chronic Stroke, Hemiparesis, Arm Paralysis
Interventions: CTX0E03 Drug Product and delivery device, Placebo; Combination Product · Drug
Lead sponsor: ReNeuron Limited; Industry
Eligibility: 35 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 23
States / cities: Little Rock, Arkansas • Irvine, California • Los Angeles, California + 19 more

Conditions: Behavior, Child
Interventions: TCIT, Booster; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Months and older
Enrollment: 622 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 4
States / cities: Miami, Florida

Conditions: Acute Lymphoblastic Leukemia
Interventions: Neurological Examination/Questionnaires; Other
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 6 Years to 28 Years
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Memphis, Tennessee

Search by objective public record fields.

Trial of Kuvan in Lesch-Nyhan Disease

ED Physical Therapy for Chronic Low Back Pain

Yoga and Mantram for Chronic Pain and PTSD

Non-invasive Prenatal Diagnostic Validation Study

Investigating the Experience of Living With Down Syndrome and Obstructive Sleep Apnea Syndrome (Stage 1)

Exercise Study of Function and Pathology for Women With X-linked Adrenoleukodystrophy

Osteoarthritis: Weakness From Inflammation

Study of SPG601 in Adult Men With Fragile X Syndrome

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome

High Risk Multiple Gestation Study

Children's Learning Centers Group FNI

Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)

Up, Down, and All Around: Evaluating Mobility Devices for Young Children With Developmental Disabilities and Delays

Sleep Intervention and Quality of Life in Down Syndrome

Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities

Cognitive Function in Rett Syndrome During Trofinetide Treatment

Behavioral Treatment of Obsessive-Compulsive Symptoms in Youth With Prader-Willi Syndrome: A Pilot Project

Use of Liquid Stable Levothyroxine in Trisomy 21 Pediatric Patients

Novel Clinical Target in Fragile X Syndrome

Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome

Impact of Competency-Based Training and Technical Assistance Employment Outcomes of Individuals With ID/DD

Investigation of Neural Stem Cells in Ischemic Stroke

Teacher Child Interaction Training (TCIT): Randomized Control Trial

Neurologic Morbidity and Disability in Acute Lymphoblastic Leukemia Survivors