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ClinicalTrials.gov public records Last synced Oct 3, 2026, 2:10 PM EDT

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Showing 49–72 of 18,681 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Diseases, Metabolic Clear all
Active, not recruiting Phase 2 Interventional

Treatment of Type 1 Diabetes With Anti-OX40L Bispecific With Anti-TNF Activity In a Single Nanobody® Molecule

NCT06812988
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Brivekimig, Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
12 Years to 35 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
5
States / cities
Atlanta, Georgia • Columbus, Georgia • Farmington Hills, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Determine the Safety, Tolerability, and Effects of GSK2374697 in Healthy Volunteers

NCT01545570
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
GSK2376497, 0.9% sodium chloride
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Incentives Targeting Gestational Weight Gain in Overweight/Obese Low Income Women

NCT02233673
View directory record Official record
Conditions
Overweight, Obesity, Pregnancy
Interventions
Financial incentives
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed Phase 1Phase 2 Interventional

Measurement of Eye Blood Flow and Renal Function in Healthy and Diabetic Patients

NCT01626469
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Captopril, placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Data for Breath Biofeedback of Dietary Compliance

NCT01043783
View directory record Official record
Conditions
Obesity
Interventions
Dietary Adherence
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Endoscopic Suturing System for Tissue Apposition

NCT00495222
View directory record Official record
Conditions
Obesity
Interventions
Tissue plication, Endoscopic Suturing System, Tissue Plication
Procedure · Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
21 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 10, 2009 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 2 Interventional Results available

Energy Metabolism in Thyroidectomized Patients

NCT04782856
View directory record Official record
Conditions
Thyroid Goiter, Hypothyroidism, Thyroid Cancer
Interventions
Levothyroxine, Liothyronine, Placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 89 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)

NCT03987295
View directory record Official record
Conditions
Frontotemporal Dementia
Interventions
AL001
Drug
Lead sponsor
Alector Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
4
States / cities
San Francisco, California • Rochester, Minnesota • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dietary Lipid Induced Insulin Resistance

NCT02757560
View directory record Official record
Conditions
Insulin Resistance
Interventions
SFA diet, MUFA diet, CARB diet
Other
Lead sponsor
Phoenix VA Health Care System
Federal
Eligibility
40 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 3 Interventional Results available

Gan & Lee Insulin Glargine Target Type (1) Evaluating Research

NCT03371082
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Gan & Lee Insulin Glargine Injection, Lantus®
Biological
Lead sponsor
Gan and Lee Pharmaceuticals, USA
Industry
Eligibility
18 Years to 75 Years
Enrollment
576 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
50
States / cities
Birmingham, Alabama • Fresno, California • Newport Beach, California + 41 more
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 3 Interventional

Diabetes Support Project: Couples Intervention

NCT01017523
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Telephone support and behavior change, Diabetes self-management education
Behavioral · Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
21 Years and older
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
San Francisco, California • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2015 · Synced Oct 3, 2026, 2:10 PM EDT
Active, not recruiting Phase 4 Interventional

Bariatric Surgery vs. Semaglutide vs. Tirzepatide

NCT06803888
View directory record Official record
Conditions
Obesity and Obesity-related Medical Conditions
Interventions
Bariatric Surgery, Semaglutide, Tirzepatide
Procedure · Drug
Lead sponsor
Ali Aminian
Other
Eligibility
18 Years to 70 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed Phase 2 Interventional

Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis

NCT00004346
View directory record Official record
Conditions
Cerebrotendinous Xanthomatosis
Interventions
chenodeoxycholic acid, lovastatin
Drug
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
0 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1996
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional

Circadian Mechanisms, Glucose, and CV Risks in T1D

NCT06624046
View directory record Official record
Conditions
Type 1 Diabetes (T1D)
Interventions
Sleep stability intervention
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Fish Oil on Plasma Triglycerides in Adults

NCT00804427
View directory record Official record
Conditions
Hypertriglyceridemia
Interventions
Fish oil (90% triglycerides), Fish oil (60% triglycerides), Fish oil (ethyl esters), Soy oil
Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed Not applicable Interventional

Fit-One: A Trial Evaluating the Effect of One Drop and Fitbit on Diabetes and Pre-diabetes Outcomes

NCT03459573
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, PreDiabetes
Interventions
One Drop | Experts On Track, One Drop | Experts On Call, One Drop | Experts Revive
Behavioral
Lead sponsor
Chandra Osborn, PhD, MPH
Industry
Eligibility
18 Years to 75 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2019 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bisphenol A and Muscle Insulin Sensitivity

NCT03771066
View directory record Official record
Conditions
Insulin Sensitivity, Glucose Metabolism Disorders, Microtia
Interventions
bisphenol A, Placebo
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Functional Fitness for Overweight or Obese Adults With Mobility Disabilities

NCT05880966
View directory record Official record
Conditions
Mobility Limitation, Overweight or Obesity, Physical Disability
Interventions
Functional Fitness
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 64 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)

NCT02470156
View directory record Official record
Conditions
Obesity, Physical Activity, Diabetes
Interventions
High Intensity Arm (Intervention), Low Intensity Arm (Comparison)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
556 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 3, 2026, 2:10 PM EDT
Active, not recruiting No phase listed Observational

Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS)

NCT01323322
View directory record Official record
Conditions
Diabetes, Cerebrovascular Disease, Age-Associated Decline, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
30 Years to 64 Years
Enrollment
3,720 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Planned CORR: Planned Care for Obesity and Risk Reduction

NCT01134029
View directory record Official record
Conditions
Obesity, Cardiovascular Risk Factors
Interventions
Stepped Care
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
25 Years to 70 Years
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2014 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Can a Brief Primary Care Intervention Affect Healthy Weight Habits

NCT01533896
View directory record Official record
Conditions
Obesity
Interventions
Grow Nicely
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
Not listed
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 15, 2012 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 2 Interventional

Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases

NCT00003662
View directory record Official record
Conditions
Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Thymic Carcinoma
Interventions
anti-thymocyte globulin, busulfan, cyclophosphamide, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy
Biological · Drug · Procedure + 1 more
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
15
States / cities
Gainesville, Florida • Jacksonville, Florida • Tampa, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2011 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SMART 2.0: Social Mobile Approaches to Reducing weighT in Young Adults

NCT03907462
View directory record Official record
Conditions
Overweight and Obesity
Interventions
SMART 2.0
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 35 Years
Enrollment
638 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 3, 2026, 2:10 PM EDT