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ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:55 AM EST

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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Distal Femoral Clear all

Conditions: Distal Femur Fracture
Interventions: Single distal femur implant, Dual distal femur implants; Procedure
Lead sponsor: University of Utah; Other
Eligibility: 60 Years to 100 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 5
States / cities: Rochester, Minnesota • New York, New York • Portland, Oregon + 2 more

Conditions: Femoral Shaft Fracture
Interventions: TRIGEN SURESHOT Distal Targeting Instrumentation., Free-hand technique; Device · Other
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 6
States / cities: Sacramento, California • Gainesville, Florida • Baltimore, Maryland + 3 more

Conditions: Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture, Patella Fracture, Tibial Shaft Fracture with or Without Associated Fibula Fracture, Ankle Fracture (bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Tibial Pilon Fracture, Talar Head, Neck, Body, or Process Fractures, Calcaneus Fractures, Lisfranc Injuries, Isolated or Multiple Metatarsal Fractures, Phalanx Fractures of the Foot, Single or Multiple, Clavicle Fractures, Proximal Humerus Fractures, Humeral Shaft Fractures, Distal Humerus Fractures (intra or Extra-articular), Olecranon Fractures, Radial Head or Neck Fractures, Elbow Fractures Involving a Combination of Fractures of the Radius and Uln, Forearm Fractures (both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft), Distal Radius Fractures
Interventions: Opioid-free pain treatment; Other
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Femur Fracture, Tibial Fractures, Nonunion of Fracture, Nonunion of Fracture of Tibia, Nonunion of Fracture of Femur (Diagnosis), Tibia Fracture
Interventions: Distal targeting jig, Free-hand/perfect circles technique; Device · Procedure
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Lower Thighbone and Knee Joint Replacement
Interventions: ComPreSs Distal Femoral Replacement System.; Device
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 10 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Femoral Fractures
Interventions: Abaloparatide, Placebo; Drug
Lead sponsor: Daniel Horwitz; Other
Eligibility: 65 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Danville, Pennsylvania

Conditions: Distal Femoral, Proximal Tibial, Knee Surgery
Interventions: Indocyanin Green Dye (ICG); Diagnostic Test
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Distal Femur Fractures
Interventions: DLS 5.0 (Dynamic locking screws), SLS (Standard locking screw); Device
Lead sponsor: AO Innovation Translation Center; Other
Eligibility: 21 Years to 120 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 5
States / cities: Sacramento, California • Columbia, Missouri • St Louis, Missouri + 2 more

Conditions: Femoral Fractures
Interventions: 95-degree Angled Blade Plate, 4.5mm Condylar Locking Plate; Device
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 16 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Fracture of Distal Femur
Interventions: Not listed
Lead sponsor: Legacy Biomechanics Laboratory; Other
Eligibility: 17 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Distal Femur Fracture
Interventions: Distal femur plates; Device
Lead sponsor: AO Innovation Translation Center; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2025
U.S. locations: 3
States / cities: Sacramento, California • Houston, Texas • Fairfax, Virginia

Conditions: Spinal Cord Injury, Osteoporosis
Interventions: Fosamax, Placebo; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 100 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: Rochester, New York

Conditions: Distal Femur Fractures
Interventions: Placement of RSA beads; Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Femoral Fractures
Interventions: reamed, interlocking intramedullary nail, locking periarticular plate; Device
Lead sponsor: Boston Medical Center; Other
Eligibility: Not listed
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2016
U.S. locations: 22
States / cities: Sacramento, California • Tampa, Florida • Indianapolis, Indiana + 18 more

Conditions: Osteoporosis, Arthroplasties, Knee Replacement
Interventions: Abaloparatide; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 55 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Femur Fracture
Interventions: Depuy Synthes Advanced Retrograde femoral nail; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Distal Radius Fracture, Osteoporosis, Hip Fractures
Interventions: Reference Point Indentation; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 50 Years to 100 Years
Enrollment: 190 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2030
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tibial Fractures, Femoral Fractures
Interventions: free-hand, Wand technique; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Articular Fractures
Interventions: Single Implant Fixation, Dual Implant Fixation; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 16
States / cities: Birmingham, Alabama • Los Angeles, California • Atlanta, Georgia + 13 more

Conditions: Distal Femur Fracture
Interventions: Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture, Koos Jr assesment on subjects with DFR of distal femur fracture; Other
Lead sponsor: University of Florida; Other
Eligibility: 55 Years to 100 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Articular Fractures
Interventions: Single Implant Fixation, Dual Implant Fixation; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 55 Years and older
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Distal Femur Fracture
Interventions: Carbo-fix Lateral Plate Device, Standard Plate-Nail Construct; Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Distal Femur Fracture
Interventions: Device - Prism Medical FGA-700 Bariatric Floor Lift; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 55 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Distal Femur Fractures
Interventions: Non Weight bearing, Early Weight Bearing; Other
Lead sponsor: St. Louis University; Other
Eligibility: 64 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 6
States / cities: Atlanta, Georgia • St Louis, Missouri • Durham, North Carolina + 3 more

Search by objective public record fields.

Dual Implant Versus Single Implant Distal End of Femur

TRIGEN SURESHOT™ Distal Targeting System Study

Opioid-Free Pain Treatment in Trauma Patients

Distal Targeter vs Free-hand

Evaluation of the Compress Distal Femoral Replacement System

Supracondylar Distal Femur Fractures and Abaloparatide

Subchondral Perfusion Mapping Using Indocyanin Green Laser

Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation

Plate Fixation of Distal Femur Fractures: A Protocol for a Study of Two Plate Options

Plating of Distal Femur Fractures by Far Cortical Locking Using MotionLoc Screws

Locking Plates for Distal Femur Fractures - a Multicenter Case Review

Pilot Study of Fosamax in Spinal Cord Injury

Radiostereometric Analysis of Fracture Healing in Distal Femur Fractures

A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures

Abaloparatide Before Total Knee Arthroplasty

RFN-Advanced Retrograde Femoral Nailing System

Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk

Distal Locking Using an Electromagnetic Field Guided Computer Based Real Time System for Orthopaedic Trauma Patients

Single Versus Dual Implant Fixation of Distal Femur Fractures

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

Geriatric Distal Femur

Carbo-fix Lateral Plate Devices and Standard Plate-Nail Constructs in Distal Femur Fractures

Mobile Weight-Support Therapy (MWeST) for Mobility After Geriatric Fracture

Early Weight Bearing on Supracondylar Distal Femur Fractures in Elderly Patients