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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:05 PM EDT

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Showing 169–192 of 288 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Distension Clear all
Completed Phase 4 Interventional

Botox or Botox With Esophageal Dilation in Patients With Achalasia

NCT03654066
View directory record Official record
Conditions
Achalasia
Interventions
Botulinum toxin type A, Endoscope balloon dilator, Patient reported outcomes, Barium esophagram
Drug · Device · Other + 1 more
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 3 Interventional Results available

Corneal Collagen Cross-Linking for Ectasia (CXL)

NCT00674661
View directory record Official record
Conditions
Ectasia
Interventions
riboflavin ophthalmic solution, UVA Irradiation
Drug · Device
Lead sponsor
Glaukos Corporation
Industry
Eligibility
14 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
10
States / cities
La Jolla, California • San Diego, California • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting

NCT04649177
View directory record Official record
Conditions
Keratoconus, Ocular Surface Disease, Pellucid Marginal Corneal Degeneration, Ectasia, Corneal Trauma, Corneal Scar, Dry Eye Syndromes, Keratoconjunctivitis Sicca, Sjogren's Syndrome
Interventions
Ocular surface optical coherence tomography
Device
Lead sponsor
Boston Sight
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Needham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Study: Effects of Strawberries on Blood Pressure

NCT01190319
View directory record Official record
Conditions
Pre-hypertension
Interventions
Strawberry Beverage, Placebo
Other
Lead sponsor
University of California, Davis
Other
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2017 · Synced Oct 20, 2026, 10:05 PM EDT
Not yet recruiting Not applicable Interventional

A Plant-Based Diet in the Treatment of Coronary Microvascular Dysfunction

NCT07821372
View directory record Official record
Conditions
Coronary Microvascular Dysfunction
Interventions
Polyphenol-Rich Plant-Based Diet
Other
Lead sponsor
Emory University
Other
Eligibility
45 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ultrasound Assessment of DILAPAN-S

NCT04529837
View directory record Official record
Conditions
Cervical Dilation, Induction of Labor, Ultrasound Evaluation
Interventions
Gauze, No gauze
Other
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 9, 2023 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 2 Interventional

Safety and Effectiveness of the PXL Platinum 330 System for Corneal Collagen Cross-Linking in Eyes With Corneal Thinning Position

NCT04213885
View directory record Official record
Conditions
Keratoconus, Unstable, Ectasia Corneal, Bacterial Keratitis
Interventions
PXL 330 Platinum device/Riboflavin
Combination Product
Lead sponsor
Eye Specialists of Indiana
Other
Eligibility
12 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Effectiveness of Digestive Enzymes at Reducing Bloating and Stomach Distension

NCT05520411
View directory record Official record
Conditions
Stomach Distended, Bloating
Interventions
HUM Flatter Me
Dietary Supplement
Lead sponsor
HUM Nutrition, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Wearing-Off Period of Pharmacological Dilation and Anisocoria

NCT05238233
View directory record Official record
Conditions
Anisocoria
Interventions
Tropicamide, 1% Pilocarpine, Proparacaine Hydrochloride, Tono pen AVIA, VG4 Gonio, Reichert phoropter
Drug · Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Acetate and Age-associated Arterial Dysfunction

NCT05424263
View directory record Official record
Conditions
Aging, Vascular Stiffness, Vascular Dilation
Interventions
Calcium Acetate Oral Solution, Calcium Carbonate Oral Suspension
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Not listed Phase 3 Interventional

Corneal Cross-Linking Comparing Variables

NCT02095730
View directory record Official record
Conditions
Unstable Corneas
Interventions
Epithelium-On Riboflavin, Epithelium-Off Riboflavin, UV Light - Continuous Beam, UV Pulsed Beam
Drug · Device
Lead sponsor
Crowd Health Research, LTD
Other
Eligibility
12 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
16
States / cities
Santa Rosa, California • Denver, Colorado • Jacksonville, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2014 · Synced Oct 20, 2026, 10:05 PM EDT
Recruiting Not applicable Interventional

Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and AV Fistula Maturation (AMPLIFI-1)

NCT07211035
View directory record Official record
Conditions
End Stage Kidney Disease (ESRD)
Interventions
The Amplifi System is a temporary extracorporeal blood pump designed to deliver controlled flow through a peripheral vein for 24-72 hours prior to AVF creation., Standard of Care (AVF creation)
Device · Procedure
Lead sponsor
Amplifi Vascular, Inc.
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Terminated Not applicable Interventional

Physical Exam Indicated Cerclage in Twin Gestations

NCT02490384
View directory record Official record
Conditions
Twin Pregnancy, Antepartum Condition or Complication, Preterm Birth, Cervical Dilation Premature
Interventions
Physical exam indicated cerclage
Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Albany, New York • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 1 Interventional Results available

Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium

NCT01623050
View directory record Official record
Conditions
Sinusitis
Interventions
SinuSys Dilation System
Device
Lead sponsor
SinuSys Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Tucson, Arizona • Palo Alto, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

'Levonorgestrel IUD Insertion After D&E Procedure

NCT00475228
View directory record Official record
Conditions
Contraceptive Usage
Interventions
Levonorgestrel IUD
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

Effects of Oxytocin on Bleeding Outcomes During Dilation and Evacuation

NCT02083809
View directory record Official record
Conditions
Abortion, Dilation and Evacuation, Hemorrhage, Blood Loss
Interventions
intravenous oxytocin, Intravenous Fluids and Electrolytes
Drug
Lead sponsor
University of Hawaii
Other
Eligibility
14 Years to 50 Years · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Honolulu, Hawaii • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 20, 2026, 10:05 PM EDT
Completed No phase listed Observational

Point-of-Care Focused Cardiac Ultrasound in Assessing the Thoracic Aorta

NCT01671618
View directory record Official record
Conditions
Aortic Aneurysm, Thoracic, Aortic Dissection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 30, 2016 · Synced Oct 20, 2026, 10:05 PM EDT
Recruiting Phase 2Phase 3 Interventional

Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal Ectasia

NCT07841470
View directory record Official record
Conditions
Keratoconus, Corneal Ectasia
Interventions
Riboflavin 0.1% ophthalmic solution and pulsed light, Riboflavin 0.1% ophthalmic solution and non-pulsed light
Combination Product
Lead sponsor
Price Vision Group
Industry
Eligibility
10 Years to 90 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Cytologic Analysis of Distention Media as a Screening Test for Endometrial Cancer

NCT00462969
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Sonohysterography
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 20, 2026, 10:05 PM EDT
Suspended No phase listed Observational Accepts healthy volunteers

A Study of High-intensity Strength Training and Thoracic Aorta Dilatation

NCT06684496
View directory record Official record
Conditions
Thoracic Aorta Dilatation
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
35 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Balloon Dilation in Selected Subjects With Refractory Eustachian Tube Dysfunction

NCT02114762
View directory record Official record
Conditions
Eustachian Tube Dysfunction
Interventions
Balloon dilation of the Eustachian tube
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 20, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Medications Effect on Lenstar Measurements

NCT02780063
View directory record Official record
Conditions
Cataract
Interventions
Lenstar Biometer
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2019 · Synced Oct 20, 2026, 10:05 PM EDT
Not listed Phase 3 Interventional

Corneal Collagen Cross-Linking (CXL) Performed With "Epi-ON" Versus "Epi-OFF" in Eyes With Keratoconus and Other Corneal Ectatic Disorders

NCT03858036
View directory record Official record
Conditions
Keratoconus, Ectasia
Interventions
Ricrolin+, VEGA UV-A system
Drug · Device
Lead sponsor
Center for Sight, Sacramento, CA
Other
Eligibility
12 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2019 · Synced Oct 20, 2026, 10:05 PM EDT
Not listed Phase 4 Interventional

Pilot Study of Lovaza (Omega 3 Fatty Acids) to Improve Cardiac Antioxidant/Anti-inflammatory Profile Before Cardiac Surgery

NCT01046604
View directory record Official record
Conditions
Mitral Valve Regurgitation, Left Atrium Dilatation and Hypertrophy, Mitochondrial Dysfunction in the Heart, Cardiomyocyte Apoptosis, Cardiac Inflammation
Interventions
Lovaza group
Drug
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2013 · Synced Oct 20, 2026, 10:05 PM EDT