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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Drinking, Binge Clear all
Completed Phase 2 Interventional Results available

Prazosin for Alcohol Dependence and Posttraumatic Stress Disorder

NCT01518972
View directory record Official record
Conditions
Alcohol Abuse, Posttraumatic Stress Disorder
Interventions
Prazosin, Placebo medication
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Jul 22, 2026, 2:10 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study

NCT06687525
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
Interventions
Not listed
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 30 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Better Than Study: Targeting Heavy Alcohol Use With Naltrexone Among Men Who Have Sex With Men (MSM)

NCT02330419
View directory record Official record
Conditions
Binge Drinking, HIV
Interventions
Placebo, Naltrexone, Medical Management (MM) counseling for alcohol use:, Urinalysis for novel alcohol biochemical markers:, Behavioral survey measurements:, Dried Blood Spot (DSB) Testing for Phosphatidylethanol, Ecological Momentary Assessment
Drug · Behavioral · Diagnostic Test
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2025 · Synced Jul 22, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use

NCT06318975
View directory record Official record
Conditions
Alcohol Drinking, Binge Drinking, Text Messaging
Interventions
Brief Alcohol Intervention, Automated and Targeted Text Messages
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
7,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Brief Alcohol Intervention (BI) for Binge Drinking HIV At-Risk and Infected Women

NCT01125371
View directory record Official record
Conditions
Alcohol; Harmful Use, Binge Drinking, Risk Behavior, HIV Infection
Interventions
Computerized brief alcohol intervention + IVR booster calls, Computerized brief alcohol intervention, Attention Control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
439 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Phase 2 Interventional Results available

Topiramate for the Treatment of Alcohol Dependent Binge-Eating Disordered Individuals

NCT00300742
View directory record Official record
Conditions
Alcohol Dependence, Binge Eating
Interventions
Topiramate
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Charlottesville, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Phase 2 Interventional Results available

An Open Label Trial of Bupropion and Naltrexone for Binge Drinking

NCT02842073
View directory record Official record
Conditions
Binge Drinking
Interventions
Naltrexone, Bupropion
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years to 34 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 25, 2018 · Synced Jul 22, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional

Preliminary Trial of an Avatar Guided Digital Intervention for Emerging Adults

NCT07418047
View directory record Official record
Conditions
Binge Alcohol Consumption, Suicidal Ideation
Interventions
EA-Avatar, Suicide safety planning app
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 29 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Marlborough, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Jul 22, 2026, 2:10 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Multimodal Immune and Neuroendocrine Assessment in Drinkers

NCT07220148
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Alcohol Cue Reactivity and Laboratory Alcohol Administration Paradigm
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
21 Years to 25 Years
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women

NCT01849029
View directory record Official record
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors

NCT04360018
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Alcohol beverage, Placebo beverage
Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Alcohol Exposed Pregnancy Risk: EARLY Randomized Controlled Trial

NCT01446653
View directory record Official record
Conditions
Alcohol Exposed Pregnancy
Interventions
Motivational Interviewing plus feedback, Video, Informational Brochure
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
2
States / cities
Charlottesville, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional

Texting to Reduce Alcohol Misuse Pilot Trial

NCT05864235
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Control, Goal Support (GS), Coaching for Context-specific Peer Support (CCPS)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 25 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Balanced Lifestyle for Undergraduate Excellence - Mobile (Project BLUEM)

NCT04105725
View directory record Official record
Conditions
Binge Drinking, Alcohol Drinking in College, Behavior, Drinking, Behavior and Behavior Mechanisms
Interventions
Brief Motivational Intervention+Substance-Free Activity Session, Alcohol + Nutrition Education Session
Behavioral · Other
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 25 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 13, 2022 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Phase 2 Interventional Results available

Buproprion for Binge Drinking

NCT03169244
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Bupropion, Placebo Oral Tablet
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years to 44 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Jul 22, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Influence of TMS on Attention Modulation

NCT05611502
View directory record Official record
Conditions
Drinking, Alcohol
Interventions
TMS
Device
Lead sponsor
Auburn University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Jul 22, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional

Alcohol-ROC-Training

NCT05491551
View directory record Official record
Conditions
Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
Interventions
Mindfulness-Based Treatment-Regulation of Craving, Cognitive-Based Therapy-Regulation of Craving
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 26 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Berkeley, California • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Care for Unhealthy Alcohol Use in Primary Care

NCT04565899
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder
Interventions
Practice facilitation implementation intervention
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 22, 2026, 2:10 AM EDT
Recruiting Not applicable Interventional

Adaptation and Evaluation of Bright Horizons

NCT05743699
View directory record Official record
Conditions
Alcohol Abuse, Substance Use
Interventions
Bright Horizons, Case Management
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
10 Years to 24 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional Results available

Cognitive Retraining and Brain Stimulation for Alcohol Use

NCT02045108
View directory record Official record
Conditions
Binge Drinking
Interventions
Active Retraining, Sham TDCS, Active TDCS, Sham Retraining
Behavioral · Device
Lead sponsor
The Mind Research Network
Other
Eligibility
21 Years to 30 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce Binge Drinking

NCT01126164
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Parent Handbook and Peer Basics
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 25 Years
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Jul 22, 2026, 2:10 AM EDT
Completed Phase 2 Interventional

Project CHOICES Efficacy Study

NCT00153478
View directory record Official record
Conditions
Risk for an Alcohol-Exposed Pregnancy, Hazardous Alcohol Use, Risk for Unintended Pregnancy
Interventions
Brief Motivational Counseling
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years to 44 Years · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
11
States / cities
Fort Lauderdale, Florida • Dayton, Texas • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2005 · Synced Jul 22, 2026, 2:10 AM EDT