- Conditions
- Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
- Interventions
- Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg
- Drug
- Lead sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
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Showing 25–48
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- Conditions
- Alcohol Use Disorder
- Interventions
- CI-581a, CI-581b, MBRP, MET
- Drug · Behavioral
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Caries, Metabolomic Profile
- Interventions
- Drinking water, Apple juice
- Other
- Lead sponsor
- Jodi Stookey
- Government
- Eligibility
- 5 Years to 10 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Heavy Drinking, Alcohol Dependence, Alcohol Use Disorder
- Interventions
- Oral naltrexone (PO-NTX), Extended-release injectable naltrexone (XR-NTX)
- Drug
- Lead sponsor
- Boston University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR)
- Interventions
- Alcohol
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 30 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Alcohol Use Disorder (AUD), Alcohol-Related Disorders
- Interventions
- Diclofenac 100mg, Diclofenac 75mg, Diclofenac 50mg, Placebo control
- Drug
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Catonsville, Maryland
- Conditions
- Heavy Drinking, Mental Health Issue
- Interventions
- LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 274 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Spinal Cord Injury Cervical
- Interventions
- Water Faucet
- Device
- Lead sponsor
- Old Dominion University
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Norfolk, Virginia
- Conditions
- Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes, Heart Failure, Hypertension, Anxiety, Chronic Pain, Depression, Fibromyalgia, Insomnia, Irritable Bowel Syndrome, Problem Drinking, Substance Use Disorder
- Interventions
- Integration
- Other
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4,025 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Alcohol Use, Personalized Normative Feedback
- Interventions
- Online Personalized Normative Feedback Intervention Targeting Alcohol Misuse, Mental Health and Substance Use Resources
- Behavioral
- Lead sponsor
- Georgia State University
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 461 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Alcohol Use, Unspecified
- Interventions
- Episodic Future thinking, Volitional choice, Monitoring only
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Alcohol Drinking, Adolescent, Drinking Behavior, Drinking, Alcohol, Adolescent Behavior
- Interventions
- BIPAS Alcohol
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Alcohol Drinking
- Interventions
- Alcohol Cue Reactivity and Laboratory Alcohol Administration Paradigm
- Behavioral
- Lead sponsor
- Auburn University
- Other
- Eligibility
- 21 Years to 25 Years
- Enrollment
- 234 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Auburn, Alabama
- Conditions
- Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
- Interventions
- Stepped Care Management
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 121 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Alcohol Drinking, Wounds and Injuries
- Interventions
- Brief Motivational Interview
- Behavioral
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 830 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2027
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Alcohol Use
- Interventions
- Customizable personalized normative feedback (CPNF), Personalized normative feedback (PNF), Attention-Matched Control (AMC)
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Cannabis Use, Alcohol Use, Inflammation
- Interventions
- Not listed
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 77 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Alcohol Drinking, Racism
- Interventions
- Alcohol administration, Placebo, No Alcohol
- Other
- Lead sponsor
- University of Houston
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Alcohol Drinking, Chronic Inflammation, Neurocognitive Dysfunction, Liver Diseases, HIV Infections
- Interventions
- Contingency Management (CM)
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 57 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2024
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Heavy Drinking
- Interventions
- Active RAVANS, Brief Mindfulness-Based Intervention
- Device · Behavioral
- Lead sponsor
- Cambridge Health Alliance
- Other
- Eligibility
- 21 Years to 29 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Malden, Massachusetts
- Conditions
- Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
- Interventions
- Mindfulness Based Relapse Prevention, Control (CTL)
- Behavioral
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 18 Years to 26 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Alcohol Use Disorder (AUD), PTSD
- Interventions
- CBT + expressive writing, Wait-List Control
- Behavioral
- Lead sponsor
- University of Rhode Island
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Alcohol Drinking
- Interventions
- Topiramate, Placebo
- Drug
- Lead sponsor
- Brown University
- Other
- Eligibility
- 14 Years to 24 Years
- Enrollment
- 82 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2017
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Drunk Driving
- Interventions
- Contingency Management, Control
- Behavioral
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 158 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- San Antonio, Texas